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Side-by-side financial comparison of PTC THERAPEUTICS, INC. (PTCT) and Riot Platforms, Inc. (RIOT). Click either name above to swap in a different company.

PTC THERAPEUTICS, INC. is the larger business by last-quarter revenue ($164.7M vs $152.8M, roughly 1.1× Riot Platforms, Inc.). PTC THERAPEUTICS, INC. runs the higher net margin — -82.0% vs -452.0%, a 370.0% gap on every dollar of revenue. On growth, Riot Platforms, Inc. posted the faster year-over-year revenue change (7.2% vs -22.7%). PTC THERAPEUTICS, INC. produced more free cash flow last quarter ($-36.6M vs $-774.3M). Over the past eight quarters, Riot Platforms, Inc.'s revenue compounded faster (38.8% CAGR vs -11.5%).

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

Riot Platforms, Inc. is a leading U.S.-based enterprise focused on Bitcoin mining, operating multiple large-scale, energy-efficient data centers across North America. It also invests in blockchain infrastructure development and holds Bitcoin as a core long-term reserve asset, centering its business strategy around the digital asset ecosystem.

PTCT vs RIOT — Head-to-Head

Bigger by revenue
PTCT
PTCT
1.1× larger
PTCT
$164.7M
$152.8M
RIOT
Growing faster (revenue YoY)
RIOT
RIOT
+30.0% gap
RIOT
7.2%
-22.7%
PTCT
Higher net margin
PTCT
PTCT
370.0% more per $
PTCT
-82.0%
-452.0%
RIOT
More free cash flow
PTCT
PTCT
$737.7M more FCF
PTCT
$-36.6M
$-774.3M
RIOT
Faster 2-yr revenue CAGR
RIOT
RIOT
Annualised
RIOT
38.8%
-11.5%
PTCT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
PTCT
PTCT
RIOT
RIOT
Revenue
$164.7M
$152.8M
Net Profit
$-135.0M
$-690.7M
Gross Margin
Operating Margin
-43.3%
-447.9%
Net Margin
-82.0%
-452.0%
Revenue YoY
-22.7%
7.2%
Net Profit YoY
-104.8%
-606.3%
EPS (diluted)
$-1.63
$-1.89

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PTCT
PTCT
RIOT
RIOT
Q4 25
$164.7M
$152.8M
Q3 25
$211.0M
$180.2M
Q2 25
$178.9M
$153.0M
Q1 25
$1.2B
$161.4M
Q4 24
$213.2M
$142.6M
Q3 24
$196.8M
$84.8M
Q2 24
$186.7M
$70.0M
Q1 24
$210.1M
$79.3M
Net Profit
PTCT
PTCT
RIOT
RIOT
Q4 25
$-135.0M
$-690.7M
Q3 25
$15.9M
$104.5M
Q2 25
$-64.8M
$219.5M
Q1 25
$866.6M
$-296.4M
Q4 24
$-65.9M
$136.4M
Q3 24
$-106.7M
$-154.4M
Q2 24
$-99.2M
$-84.4M
Q1 24
$-91.6M
$211.8M
Operating Margin
PTCT
PTCT
RIOT
RIOT
Q4 25
-43.3%
-447.9%
Q3 25
1.4%
44.4%
Q2 25
-19.5%
Q1 25
82.5%
-144.9%
Q4 24
-76.2%
Q3 24
-27.7%
-143.3%
Q2 24
-21.5%
-167.2%
Q1 24
-21.6%
Net Margin
PTCT
PTCT
RIOT
RIOT
Q4 25
-82.0%
-452.0%
Q3 25
7.5%
58.0%
Q2 25
-36.3%
143.4%
Q1 25
73.7%
-183.6%
Q4 24
-30.9%
95.7%
Q3 24
-54.2%
-182.1%
Q2 24
-53.1%
-120.6%
Q1 24
-43.6%
267.1%
EPS (diluted)
PTCT
PTCT
RIOT
RIOT
Q4 25
$-1.63
$-1.89
Q3 25
$0.20
$0.26
Q2 25
$-0.83
$0.58
Q1 25
$10.04
$-0.90
Q4 24
$-0.85
$0.39
Q3 24
$-1.39
$-0.54
Q2 24
$-1.29
$-0.32
Q1 24
$-1.20
$0.51

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PTCT
PTCT
RIOT
RIOT
Cash + ST InvestmentsLiquidity on hand
$1.9B
$233.5M
Total DebtLower is stronger
$840.8M
Stockholders' EquityBook value
$-205.3M
$2.9B
Total Assets
$2.9B
$3.9B
Debt / EquityLower = less leverage
0.29×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PTCT
PTCT
RIOT
RIOT
Q4 25
$1.9B
$233.5M
Q3 25
$1.7B
$330.7M
Q2 25
$2.0B
$255.4M
Q1 25
$2.0B
$163.7M
Q4 24
$1.1B
$277.9M
Q3 24
$1.0B
$355.7M
Q2 24
$1.1B
$481.2M
Q1 24
$884.8M
$688.5M
Total Debt
PTCT
PTCT
RIOT
RIOT
Q4 25
$840.8M
Q3 25
$5.3M
Q2 25
$5.3M
Q1 25
$5.3M
Q4 24
$584.6M
Q3 24
$5.7M
Q2 24
Q1 24
Stockholders' Equity
PTCT
PTCT
RIOT
RIOT
Q4 25
$-205.3M
$2.9B
Q3 25
$-155.8M
$3.5B
Q2 25
$-206.5M
$3.3B
Q1 25
$-185.8M
$2.9B
Q4 24
$-1.1B
$3.1B
Q3 24
$-1.1B
$2.7B
Q2 24
$-980.2M
$2.6B
Q1 24
$-893.9M
$2.5B
Total Assets
PTCT
PTCT
RIOT
RIOT
Q4 25
$2.9B
$3.9B
Q3 25
$2.6B
$4.5B
Q2 25
$2.6B
$4.3B
Q1 25
$2.7B
$3.7B
Q4 24
$1.7B
$3.9B
Q3 24
$1.8B
$2.9B
Q2 24
$1.9B
$2.7B
Q1 24
$1.8B
$2.6B
Debt / Equity
PTCT
PTCT
RIOT
RIOT
Q4 25
0.29×
Q3 25
0.00×
Q2 25
0.00×
Q1 25
0.00×
Q4 24
0.19×
Q3 24
0.00×
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PTCT
PTCT
RIOT
RIOT
Operating Cash FlowLast quarter
$-34.3M
$-572.9M
Free Cash FlowOCF − Capex
$-36.6M
$-774.3M
FCF MarginFCF / Revenue
-22.3%
-506.6%
Capex IntensityCapex / Revenue
1.4%
131.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$702.3M
$-1.4B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PTCT
PTCT
RIOT
RIOT
Q4 25
$-34.3M
$-572.9M
Q3 25
$-66.3M
$-114.0M
Q2 25
$-58.3M
$-231.3M
Q1 25
$870.1M
$-122.1M
Q4 24
$-30.0M
$-255.1M
Q3 24
$-77.0M
$-56.3M
Q2 24
$-71.5M
$-42.5M
Q1 24
$70.8M
$-57.9M
Free Cash Flow
PTCT
PTCT
RIOT
RIOT
Q4 25
$-36.6M
$-774.3M
Q3 25
$-69.7M
$-139.7M
Q2 25
$-59.6M
$-291.7M
Q1 25
$868.4M
$-154.9M
Q4 24
$-33.8M
$-495.4M
Q3 24
$-77.5M
$-127.6M
Q2 24
$-78.8M
$-96.1M
Q1 24
$61.2M
$-115.2M
FCF Margin
PTCT
PTCT
RIOT
RIOT
Q4 25
-22.3%
-506.6%
Q3 25
-33.1%
-77.5%
Q2 25
-33.3%
-190.7%
Q1 25
73.8%
-96.0%
Q4 24
-15.8%
-347.5%
Q3 24
-39.4%
-150.5%
Q2 24
-42.2%
-137.2%
Q1 24
29.1%
-145.2%
Capex Intensity
PTCT
PTCT
RIOT
RIOT
Q4 25
1.4%
131.8%
Q3 25
1.6%
14.3%
Q2 25
0.7%
39.5%
Q1 25
0.1%
20.4%
Q4 24
1.8%
168.6%
Q3 24
0.3%
84.1%
Q2 24
4.0%
76.5%
Q1 24
4.6%
72.3%
Cash Conversion
PTCT
PTCT
RIOT
RIOT
Q4 25
Q3 25
-4.17×
-1.09×
Q2 25
-1.05×
Q1 25
1.00×
Q4 24
-1.87×
Q3 24
Q2 24
Q1 24
-0.27×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

PTCT
PTCT

Segment breakdown not available.

RIOT
RIOT

Bitcoin Mining Segment$131.7M86%
Engineering Segment$21.1M14%

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