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Side-by-side financial comparison of PTC THERAPEUTICS, INC. (PTCT) and Riot Platforms, Inc. (RIOT). Click either name above to swap in a different company.
PTC THERAPEUTICS, INC. is the larger business by last-quarter revenue ($164.7M vs $152.8M, roughly 1.1× Riot Platforms, Inc.). PTC THERAPEUTICS, INC. runs the higher net margin — -82.0% vs -452.0%, a 370.0% gap on every dollar of revenue. On growth, Riot Platforms, Inc. posted the faster year-over-year revenue change (7.2% vs -22.7%). PTC THERAPEUTICS, INC. produced more free cash flow last quarter ($-36.6M vs $-774.3M). Over the past eight quarters, Riot Platforms, Inc.'s revenue compounded faster (38.8% CAGR vs -11.5%).
PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.
Riot Platforms, Inc. is a leading U.S.-based enterprise focused on Bitcoin mining, operating multiple large-scale, energy-efficient data centers across North America. It also invests in blockchain infrastructure development and holds Bitcoin as a core long-term reserve asset, centering its business strategy around the digital asset ecosystem.
PTCT vs RIOT — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | ||
|---|---|---|
| Revenue | $164.7M | $152.8M |
| Net Profit | $-135.0M | $-690.7M |
| Gross Margin | — | — |
| Operating Margin | -43.3% | -447.9% |
| Net Margin | -82.0% | -452.0% |
| Revenue YoY | -22.7% | 7.2% |
| Net Profit YoY | -104.8% | -606.3% |
| EPS (diluted) | $-1.63 | $-1.89 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $164.7M | $152.8M | ||
| Q3 25 | $211.0M | $180.2M | ||
| Q2 25 | $178.9M | $153.0M | ||
| Q1 25 | $1.2B | $161.4M | ||
| Q4 24 | $213.2M | $142.6M | ||
| Q3 24 | $196.8M | $84.8M | ||
| Q2 24 | $186.7M | $70.0M | ||
| Q1 24 | $210.1M | $79.3M |
| Q4 25 | $-135.0M | $-690.7M | ||
| Q3 25 | $15.9M | $104.5M | ||
| Q2 25 | $-64.8M | $219.5M | ||
| Q1 25 | $866.6M | $-296.4M | ||
| Q4 24 | $-65.9M | $136.4M | ||
| Q3 24 | $-106.7M | $-154.4M | ||
| Q2 24 | $-99.2M | $-84.4M | ||
| Q1 24 | $-91.6M | $211.8M |
| Q4 25 | -43.3% | -447.9% | ||
| Q3 25 | 1.4% | 44.4% | ||
| Q2 25 | -19.5% | — | ||
| Q1 25 | 82.5% | -144.9% | ||
| Q4 24 | -76.2% | — | ||
| Q3 24 | -27.7% | -143.3% | ||
| Q2 24 | -21.5% | -167.2% | ||
| Q1 24 | -21.6% | — |
| Q4 25 | -82.0% | -452.0% | ||
| Q3 25 | 7.5% | 58.0% | ||
| Q2 25 | -36.3% | 143.4% | ||
| Q1 25 | 73.7% | -183.6% | ||
| Q4 24 | -30.9% | 95.7% | ||
| Q3 24 | -54.2% | -182.1% | ||
| Q2 24 | -53.1% | -120.6% | ||
| Q1 24 | -43.6% | 267.1% |
| Q4 25 | $-1.63 | $-1.89 | ||
| Q3 25 | $0.20 | $0.26 | ||
| Q2 25 | $-0.83 | $0.58 | ||
| Q1 25 | $10.04 | $-0.90 | ||
| Q4 24 | $-0.85 | $0.39 | ||
| Q3 24 | $-1.39 | $-0.54 | ||
| Q2 24 | $-1.29 | $-0.32 | ||
| Q1 24 | $-1.20 | $0.51 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | ||
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $1.9B | $233.5M |
| Total DebtLower is stronger | — | $840.8M |
| Stockholders' EquityBook value | $-205.3M | $2.9B |
| Total Assets | $2.9B | $3.9B |
| Debt / EquityLower = less leverage | — | 0.29× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $1.9B | $233.5M | ||
| Q3 25 | $1.7B | $330.7M | ||
| Q2 25 | $2.0B | $255.4M | ||
| Q1 25 | $2.0B | $163.7M | ||
| Q4 24 | $1.1B | $277.9M | ||
| Q3 24 | $1.0B | $355.7M | ||
| Q2 24 | $1.1B | $481.2M | ||
| Q1 24 | $884.8M | $688.5M |
| Q4 25 | — | $840.8M | ||
| Q3 25 | — | $5.3M | ||
| Q2 25 | — | $5.3M | ||
| Q1 25 | — | $5.3M | ||
| Q4 24 | — | $584.6M | ||
| Q3 24 | — | $5.7M | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | $-205.3M | $2.9B | ||
| Q3 25 | $-155.8M | $3.5B | ||
| Q2 25 | $-206.5M | $3.3B | ||
| Q1 25 | $-185.8M | $2.9B | ||
| Q4 24 | $-1.1B | $3.1B | ||
| Q3 24 | $-1.1B | $2.7B | ||
| Q2 24 | $-980.2M | $2.6B | ||
| Q1 24 | $-893.9M | $2.5B |
| Q4 25 | $2.9B | $3.9B | ||
| Q3 25 | $2.6B | $4.5B | ||
| Q2 25 | $2.6B | $4.3B | ||
| Q1 25 | $2.7B | $3.7B | ||
| Q4 24 | $1.7B | $3.9B | ||
| Q3 24 | $1.8B | $2.9B | ||
| Q2 24 | $1.9B | $2.7B | ||
| Q1 24 | $1.8B | $2.6B |
| Q4 25 | — | 0.29× | ||
| Q3 25 | — | 0.00× | ||
| Q2 25 | — | 0.00× | ||
| Q1 25 | — | 0.00× | ||
| Q4 24 | — | 0.19× | ||
| Q3 24 | — | 0.00× | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | ||
|---|---|---|
| Operating Cash FlowLast quarter | $-34.3M | $-572.9M |
| Free Cash FlowOCF − Capex | $-36.6M | $-774.3M |
| FCF MarginFCF / Revenue | -22.3% | -506.6% |
| Capex IntensityCapex / Revenue | 1.4% | 131.8% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $702.3M | $-1.4B |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-34.3M | $-572.9M | ||
| Q3 25 | $-66.3M | $-114.0M | ||
| Q2 25 | $-58.3M | $-231.3M | ||
| Q1 25 | $870.1M | $-122.1M | ||
| Q4 24 | $-30.0M | $-255.1M | ||
| Q3 24 | $-77.0M | $-56.3M | ||
| Q2 24 | $-71.5M | $-42.5M | ||
| Q1 24 | $70.8M | $-57.9M |
| Q4 25 | $-36.6M | $-774.3M | ||
| Q3 25 | $-69.7M | $-139.7M | ||
| Q2 25 | $-59.6M | $-291.7M | ||
| Q1 25 | $868.4M | $-154.9M | ||
| Q4 24 | $-33.8M | $-495.4M | ||
| Q3 24 | $-77.5M | $-127.6M | ||
| Q2 24 | $-78.8M | $-96.1M | ||
| Q1 24 | $61.2M | $-115.2M |
| Q4 25 | -22.3% | -506.6% | ||
| Q3 25 | -33.1% | -77.5% | ||
| Q2 25 | -33.3% | -190.7% | ||
| Q1 25 | 73.8% | -96.0% | ||
| Q4 24 | -15.8% | -347.5% | ||
| Q3 24 | -39.4% | -150.5% | ||
| Q2 24 | -42.2% | -137.2% | ||
| Q1 24 | 29.1% | -145.2% |
| Q4 25 | 1.4% | 131.8% | ||
| Q3 25 | 1.6% | 14.3% | ||
| Q2 25 | 0.7% | 39.5% | ||
| Q1 25 | 0.1% | 20.4% | ||
| Q4 24 | 1.8% | 168.6% | ||
| Q3 24 | 0.3% | 84.1% | ||
| Q2 24 | 4.0% | 76.5% | ||
| Q1 24 | 4.6% | 72.3% |
| Q4 25 | — | — | ||
| Q3 25 | -4.17× | -1.09× | ||
| Q2 25 | — | -1.05× | ||
| Q1 25 | 1.00× | — | ||
| Q4 24 | — | -1.87× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | -0.27× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
PTCT
Segment breakdown not available.
RIOT
| Bitcoin Mining Segment | $131.7M | 86% |
| Engineering Segment | $21.1M | 14% |