vs
Side-by-side financial comparison of PTC THERAPEUTICS, INC. (PTCT) and Safehold Inc. (SAFE). Click either name above to swap in a different company.
PTC THERAPEUTICS, INC. is the larger business by last-quarter revenue ($164.7M vs $97.9M, roughly 1.7× Safehold Inc.). Safehold Inc. runs the higher net margin — 28.5% vs -82.0%, a 110.4% gap on every dollar of revenue. On growth, Safehold Inc. posted the faster year-over-year revenue change (6.5% vs -22.7%). Over the past eight quarters, Safehold Inc.'s revenue compounded faster (2.5% CAGR vs -11.5%).
PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.
SAFE Investment Company Limited is a Chinese sovereign wealth fund based in Hong Kong.
PTCT vs SAFE — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $164.7M | $97.9M |
| Net Profit | $-135.0M | $27.9M |
| Gross Margin | — | 98.6% |
| Operating Margin | -43.3% | 27.4% |
| Net Margin | -82.0% | 28.5% |
| Revenue YoY | -22.7% | 6.5% |
| Net Profit YoY | -104.8% | 7.1% |
| EPS (diluted) | $-1.63 | $0.38 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $164.7M | $97.9M | ||
| Q3 25 | $211.0M | $96.2M | ||
| Q2 25 | $178.9M | $93.8M | ||
| Q1 25 | $1.2B | $97.7M | ||
| Q4 24 | $213.2M | $91.9M | ||
| Q3 24 | $196.8M | $90.7M | ||
| Q2 24 | $186.7M | $89.9M | ||
| Q1 24 | $210.1M | $93.2M |
| Q4 25 | $-135.0M | $27.9M | ||
| Q3 25 | $15.9M | $29.3M | ||
| Q2 25 | $-64.8M | $27.9M | ||
| Q1 25 | $866.6M | $29.4M | ||
| Q4 24 | $-65.9M | $26.0M | ||
| Q3 24 | $-106.7M | $19.3M | ||
| Q2 24 | $-99.2M | $29.7M | ||
| Q1 24 | $-91.6M | $30.7M |
| Q4 25 | — | 98.6% | ||
| Q3 25 | — | 98.5% | ||
| Q2 25 | — | 99.1% | ||
| Q1 25 | — | 98.8% | ||
| Q4 24 | — | 98.8% | ||
| Q3 24 | — | 98.8% | ||
| Q2 24 | — | 98.8% | ||
| Q1 24 | — | 98.8% |
| Q4 25 | -43.3% | 27.4% | ||
| Q3 25 | 1.4% | 25.9% | ||
| Q2 25 | -19.5% | 25.5% | ||
| Q1 25 | 82.5% | 25.9% | ||
| Q4 24 | -76.2% | 24.6% | ||
| Q3 24 | -27.7% | 17.5% | ||
| Q2 24 | -21.5% | 26.7% | ||
| Q1 24 | -21.6% | 26.4% |
| Q4 25 | -82.0% | 28.5% | ||
| Q3 25 | 7.5% | 30.5% | ||
| Q2 25 | -36.3% | 29.8% | ||
| Q1 25 | 73.7% | 30.1% | ||
| Q4 24 | -30.9% | 28.3% | ||
| Q3 24 | -54.2% | 21.3% | ||
| Q2 24 | -53.1% | 33.0% | ||
| Q1 24 | -43.6% | 33.0% |
| Q4 25 | $-1.63 | $0.38 | ||
| Q3 25 | $0.20 | $0.41 | ||
| Q2 25 | $-0.83 | $0.39 | ||
| Q1 25 | $10.04 | $0.41 | ||
| Q4 24 | $-0.85 | $0.36 | ||
| Q3 24 | $-1.39 | $0.27 | ||
| Q2 24 | $-1.29 | $0.42 | ||
| Q1 24 | $-1.20 | $0.43 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $1.9B | $21.7M |
| Total DebtLower is stronger | — | $4.6B |
| Stockholders' EquityBook value | $-205.3M | $2.4B |
| Total Assets | $2.9B | $7.2B |
| Debt / EquityLower = less leverage | — | 1.90× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $1.9B | $21.7M | ||
| Q3 25 | $1.7B | $12.1M | ||
| Q2 25 | $2.0B | $13.9M | ||
| Q1 25 | $2.0B | $17.3M | ||
| Q4 24 | $1.1B | $8.3M | ||
| Q3 24 | $1.0B | $15.6M | ||
| Q2 24 | $1.1B | $13.4M | ||
| Q1 24 | $884.8M | $11.3M |
| Q4 25 | — | $4.6B | ||
| Q3 25 | — | $4.5B | ||
| Q2 25 | — | $4.4B | ||
| Q1 25 | — | $4.3B | ||
| Q4 24 | — | $4.3B | ||
| Q3 24 | — | $4.3B | ||
| Q2 24 | — | $4.2B | ||
| Q1 24 | — | $4.1B |
| Q4 25 | $-205.3M | $2.4B | ||
| Q3 25 | $-155.8M | $2.4B | ||
| Q2 25 | $-206.5M | $2.4B | ||
| Q1 25 | $-185.8M | $2.4B | ||
| Q4 24 | $-1.1B | $2.3B | ||
| Q3 24 | $-1.1B | $2.3B | ||
| Q2 24 | $-980.2M | $2.3B | ||
| Q1 24 | $-893.9M | $2.3B |
| Q4 25 | $2.9B | $7.2B | ||
| Q3 25 | $2.6B | $7.1B | ||
| Q2 25 | $2.6B | $7.1B | ||
| Q1 25 | $2.7B | $6.9B | ||
| Q4 24 | $1.7B | $6.9B | ||
| Q3 24 | $1.8B | $6.8B | ||
| Q2 24 | $1.9B | $6.8B | ||
| Q1 24 | $1.8B | $6.7B |
| Q4 25 | — | 1.90× | ||
| Q3 25 | — | 1.89× | ||
| Q2 25 | — | 1.87× | ||
| Q1 25 | — | 1.85× | ||
| Q4 24 | — | 1.84× | ||
| Q3 24 | — | 1.88× | ||
| Q2 24 | — | 1.81× | ||
| Q1 24 | — | 1.81× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-34.3M | $47.8M |
| Free Cash FlowOCF − Capex | $-36.6M | — |
| FCF MarginFCF / Revenue | -22.3% | — |
| Capex IntensityCapex / Revenue | 1.4% | — |
| Cash ConversionOCF / Net Profit | — | 1.72× |
| TTM Free Cash FlowTrailing 4 quarters | $702.3M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-34.3M | $47.8M | ||
| Q3 25 | $-66.3M | $-1.4M | ||
| Q2 25 | $-58.3M | $28.0M | ||
| Q1 25 | $870.1M | $8.9M | ||
| Q4 24 | $-30.0M | $37.9M | ||
| Q3 24 | $-77.0M | $8.3M | ||
| Q2 24 | $-71.5M | $24.8M | ||
| Q1 24 | $70.8M | $-3.1M |
| Q4 25 | $-36.6M | — | ||
| Q3 25 | $-69.7M | — | ||
| Q2 25 | $-59.6M | — | ||
| Q1 25 | $868.4M | — | ||
| Q4 24 | $-33.8M | — | ||
| Q3 24 | $-77.5M | — | ||
| Q2 24 | $-78.8M | — | ||
| Q1 24 | $61.2M | — |
| Q4 25 | -22.3% | — | ||
| Q3 25 | -33.1% | — | ||
| Q2 25 | -33.3% | — | ||
| Q1 25 | 73.8% | — | ||
| Q4 24 | -15.8% | — | ||
| Q3 24 | -39.4% | — | ||
| Q2 24 | -42.2% | — | ||
| Q1 24 | 29.1% | — |
| Q4 25 | 1.4% | — | ||
| Q3 25 | 1.6% | — | ||
| Q2 25 | 0.7% | — | ||
| Q1 25 | 0.1% | — | ||
| Q4 24 | 1.8% | — | ||
| Q3 24 | 0.3% | — | ||
| Q2 24 | 4.0% | — | ||
| Q1 24 | 4.6% | — |
| Q4 25 | — | 1.72× | ||
| Q3 25 | -4.17× | -0.05× | ||
| Q2 25 | — | 1.00× | ||
| Q1 25 | 1.00× | 0.30× | ||
| Q4 24 | — | 1.45× | ||
| Q3 24 | — | 0.43× | ||
| Q2 24 | — | 0.83× | ||
| Q1 24 | — | -0.10× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
PTCT
Segment breakdown not available.
SAFE
| Equity Method Investment Nonconsolidated Investee Or Group Of Investees | $60.3M | 62% |
| Other | $33.7M | 34% |
| Stabilized Properties | $3.8M | 4% |
