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Side-by-side financial comparison of PTC THERAPEUTICS, INC. (PTCT) and Southland Holdings, Inc. (SLND). Click either name above to swap in a different company.

PTC THERAPEUTICS, INC. is the larger business by last-quarter revenue ($164.7M vs $104.0M, roughly 1.6× Southland Holdings, Inc.). PTC THERAPEUTICS, INC. runs the higher net margin — -82.0% vs -208.2%, a 126.2% gap on every dollar of revenue. On growth, PTC THERAPEUTICS, INC. posted the faster year-over-year revenue change (-22.7% vs -61.1%). Southland Holdings, Inc. produced more free cash flow last quarter ($9.3M vs $-36.6M). Over the past eight quarters, PTC THERAPEUTICS, INC.'s revenue compounded faster (-11.5% CAGR vs -39.9%).

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

Southland Holdings, Inc. is a leading North American infrastructure construction firm. It offers full-suite services for transportation projects including highways, bridges and airports, water and wastewater system construction, and commercial site development, serving both public sector and private industry clients across regional core markets.

PTCT vs SLND — Head-to-Head

Bigger by revenue
PTCT
PTCT
1.6× larger
PTCT
$164.7M
$104.0M
SLND
Growing faster (revenue YoY)
PTCT
PTCT
+38.4% gap
PTCT
-22.7%
-61.1%
SLND
Higher net margin
PTCT
PTCT
126.2% more per $
PTCT
-82.0%
-208.2%
SLND
More free cash flow
SLND
SLND
$45.9M more FCF
SLND
$9.3M
$-36.6M
PTCT
Faster 2-yr revenue CAGR
PTCT
PTCT
Annualised
PTCT
-11.5%
-39.9%
SLND

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
PTCT
PTCT
SLND
SLND
Revenue
$164.7M
$104.0M
Net Profit
$-135.0M
$-216.4M
Gross Margin
-186.0%
Operating Margin
-43.3%
-202.4%
Net Margin
-82.0%
-208.2%
Revenue YoY
-22.7%
-61.1%
Net Profit YoY
-104.8%
-5108.5%
EPS (diluted)
$-1.63
$-4.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PTCT
PTCT
SLND
SLND
Q4 25
$164.7M
$104.0M
Q3 25
$211.0M
$213.3M
Q2 25
$178.9M
$215.4M
Q1 25
$1.2B
$239.5M
Q4 24
$213.2M
$267.3M
Q3 24
$196.8M
$173.3M
Q2 24
$186.7M
$251.5M
Q1 24
$210.1M
$288.1M
Net Profit
PTCT
PTCT
SLND
SLND
Q4 25
$-135.0M
$-216.4M
Q3 25
$15.9M
$-75.3M
Q2 25
$-64.8M
$-10.3M
Q1 25
$866.6M
$-4.6M
Q4 24
$-65.9M
$-4.2M
Q3 24
$-106.7M
$-54.7M
Q2 24
$-99.2M
$-46.1M
Q1 24
$-91.6M
$-406.0K
Gross Margin
PTCT
PTCT
SLND
SLND
Q4 25
-186.0%
Q3 25
1.5%
Q2 25
6.2%
Q1 25
9.0%
Q4 24
2.9%
Q3 24
-29.5%
Q2 24
-15.9%
Q1 24
7.1%
Operating Margin
PTCT
PTCT
SLND
SLND
Q4 25
-43.3%
-202.4%
Q3 25
1.4%
-5.3%
Q2 25
-19.5%
-0.1%
Q1 25
82.5%
2.1%
Q4 24
-76.2%
-3.0%
Q3 24
-27.7%
-39.6%
Q2 24
-21.5%
-22.1%
Q1 24
-21.6%
2.1%
Net Margin
PTCT
PTCT
SLND
SLND
Q4 25
-82.0%
-208.2%
Q3 25
7.5%
-35.3%
Q2 25
-36.3%
-4.8%
Q1 25
73.7%
-1.9%
Q4 24
-30.9%
-1.6%
Q3 24
-54.2%
-31.6%
Q2 24
-53.1%
-18.3%
Q1 24
-43.6%
-0.1%
EPS (diluted)
PTCT
PTCT
SLND
SLND
Q4 25
$-1.63
$-4.01
Q3 25
$0.20
$-1.39
Q2 25
$-0.83
$-0.19
Q1 25
$10.04
$-0.08
Q4 24
$-0.85
$-0.08
Q3 24
$-1.39
$-1.14
Q2 24
$-1.29
$-0.96
Q1 24
$-1.20
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PTCT
PTCT
SLND
SLND
Cash + ST InvestmentsLiquidity on hand
$1.9B
$52.7M
Total DebtLower is stronger
$257.7M
Stockholders' EquityBook value
$-205.3M
$-140.9M
Total Assets
$2.9B
$989.3M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PTCT
PTCT
SLND
SLND
Q4 25
$1.9B
$52.7M
Q3 25
$1.7B
$40.5M
Q2 25
$2.0B
$46.5M
Q1 25
$2.0B
$65.1M
Q4 24
$1.1B
$72.2M
Q3 24
$1.0B
$91.4M
Q2 24
$1.1B
$52.4M
Q1 24
$884.8M
$31.2M
Total Debt
PTCT
PTCT
SLND
SLND
Q4 25
$257.7M
Q3 25
$267.8M
Q2 25
$278.6M
Q1 25
$288.1M
Q4 24
$300.1M
Q3 24
$318.3M
Q2 24
$307.8M
Q1 24
$302.0M
Stockholders' Equity
PTCT
PTCT
SLND
SLND
Q4 25
$-205.3M
$-140.9M
Q3 25
$-155.8M
$75.0M
Q2 25
$-206.5M
$151.1M
Q1 25
$-185.8M
$159.1M
Q4 24
$-1.1B
$163.7M
Q3 24
$-1.1B
$149.1M
Q2 24
$-980.2M
$203.3M
Q1 24
$-893.9M
$249.3M
Total Assets
PTCT
PTCT
SLND
SLND
Q4 25
$2.9B
$989.3M
Q3 25
$2.6B
$1.1B
Q2 25
$2.6B
$1.2B
Q1 25
$2.7B
$1.2B
Q4 24
$1.7B
$1.2B
Q3 24
$1.8B
$1.2B
Q2 24
$1.9B
$1.3B
Q1 24
$1.8B
$1.2B
Debt / Equity
PTCT
PTCT
SLND
SLND
Q4 25
Q3 25
3.57×
Q2 25
1.84×
Q1 25
1.81×
Q4 24
1.83×
Q3 24
2.14×
Q2 24
1.51×
Q1 24
1.21×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PTCT
PTCT
SLND
SLND
Operating Cash FlowLast quarter
$-34.3M
$9.7M
Free Cash FlowOCF − Capex
$-36.6M
$9.3M
FCF MarginFCF / Revenue
-22.3%
8.9%
Capex IntensityCapex / Revenue
1.4%
0.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$702.3M
$12.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PTCT
PTCT
SLND
SLND
Q4 25
$-34.3M
$9.7M
Q3 25
$-66.3M
$5.9M
Q2 25
$-58.3M
$-5.4M
Q1 25
$870.1M
$6.4M
Q4 24
$-30.0M
$-10.3M
Q3 24
$-77.0M
$-5.3M
Q2 24
$-71.5M
$27.4M
Q1 24
$70.8M
$-9.9M
Free Cash Flow
PTCT
PTCT
SLND
SLND
Q4 25
$-36.6M
$9.3M
Q3 25
$-69.7M
$5.3M
Q2 25
$-59.6M
$-6.5M
Q1 25
$868.4M
$4.6M
Q4 24
$-33.8M
$-11.5M
Q3 24
$-77.5M
$-7.3M
Q2 24
$-78.8M
$26.3M
Q1 24
$61.2M
$-13.0M
FCF Margin
PTCT
PTCT
SLND
SLND
Q4 25
-22.3%
8.9%
Q3 25
-33.1%
2.5%
Q2 25
-33.3%
-3.0%
Q1 25
73.8%
1.9%
Q4 24
-15.8%
-4.3%
Q3 24
-39.4%
-4.2%
Q2 24
-42.2%
10.5%
Q1 24
29.1%
-4.5%
Capex Intensity
PTCT
PTCT
SLND
SLND
Q4 25
1.4%
0.4%
Q3 25
1.6%
0.3%
Q2 25
0.7%
0.5%
Q1 25
0.1%
0.7%
Q4 24
1.8%
0.5%
Q3 24
0.3%
1.1%
Q2 24
4.0%
0.4%
Q1 24
4.6%
1.1%
Cash Conversion
PTCT
PTCT
SLND
SLND
Q4 25
Q3 25
-4.17×
Q2 25
Q1 25
1.00×
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

PTCT
PTCT

Segment breakdown not available.

SLND
SLND

Civil$58.4M56%
Transportation$45.6M44%

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