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Side-by-side financial comparison of PTC THERAPEUTICS, INC. (PTCT) and UP Fintech Holding Ltd (TIGR). Click either name above to swap in a different company.
PTC THERAPEUTICS, INC. is the larger business by last-quarter revenue ($164.7M vs $107.6M, roughly 1.5× UP Fintech Holding Ltd). UP Fintech Holding Ltd runs the higher net margin — 28.4% vs -82.0%, a 110.4% gap on every dollar of revenue.
PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.
UP Fintech Holding Limited, operating under the Tiger Brokers brand, provides online financial services for global Chinese investors. It offers cross-market stock trading (US, Hong Kong, mainland China A-shares), fund management, margin financing and investor education for retail and institutional clients.
PTCT vs TIGR — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2025
| Metric | ||
|---|---|---|
| Revenue | $164.7M | $107.6M |
| Net Profit | $-135.0M | $30.6M |
| Gross Margin | — | — |
| Operating Margin | -43.3% | — |
| Net Margin | -82.0% | 28.4% |
| Revenue YoY | -22.7% | — |
| Net Profit YoY | -104.8% | — |
| EPS (diluted) | $-1.63 | $0.01 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $164.7M | — | ||
| Q3 25 | $211.0M | — | ||
| Q2 25 | $178.9M | — | ||
| Q1 25 | $1.2B | $107.6M | ||
| Q4 24 | $213.2M | — | ||
| Q3 24 | $196.8M | — | ||
| Q2 24 | $186.7M | $166.4M | ||
| Q1 24 | $210.1M | — |
| Q4 25 | $-135.0M | — | ||
| Q3 25 | $15.9M | — | ||
| Q2 25 | $-64.8M | — | ||
| Q1 25 | $866.6M | $30.6M | ||
| Q4 24 | $-65.9M | — | ||
| Q3 24 | $-106.7M | — | ||
| Q2 24 | $-99.2M | $15.2M | ||
| Q1 24 | $-91.6M | — |
| Q4 25 | -43.3% | — | ||
| Q3 25 | 1.4% | — | ||
| Q2 25 | -19.5% | — | ||
| Q1 25 | 82.5% | — | ||
| Q4 24 | -76.2% | — | ||
| Q3 24 | -27.7% | — | ||
| Q2 24 | -21.5% | 14.0% | ||
| Q1 24 | -21.6% | — |
| Q4 25 | -82.0% | — | ||
| Q3 25 | 7.5% | — | ||
| Q2 25 | -36.3% | — | ||
| Q1 25 | 73.7% | 28.4% | ||
| Q4 24 | -30.9% | — | ||
| Q3 24 | -54.2% | — | ||
| Q2 24 | -53.1% | 9.1% | ||
| Q1 24 | -43.6% | — |
| Q4 25 | $-1.63 | — | ||
| Q3 25 | $0.20 | — | ||
| Q2 25 | $-0.83 | — | ||
| Q1 25 | $10.04 | $0.01 | ||
| Q4 24 | $-0.85 | — | ||
| Q3 24 | $-1.39 | — | ||
| Q2 24 | $-1.29 | $0.01 | ||
| Q1 24 | $-1.20 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | ||
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $1.9B | — |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $-205.3M | — |
| Total Assets | $2.9B | — |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $1.9B | — | ||
| Q3 25 | $1.7B | — | ||
| Q2 25 | $2.0B | — | ||
| Q1 25 | $2.0B | — | ||
| Q4 24 | $1.1B | — | ||
| Q3 24 | $1.0B | — | ||
| Q2 24 | $1.1B | $392.5M | ||
| Q1 24 | $884.8M | — |
| Q4 25 | $-205.3M | — | ||
| Q3 25 | $-155.8M | — | ||
| Q2 25 | $-206.5M | — | ||
| Q1 25 | $-185.8M | — | ||
| Q4 24 | $-1.1B | — | ||
| Q3 24 | $-1.1B | — | ||
| Q2 24 | $-980.2M | $501.2M | ||
| Q1 24 | $-893.9M | — |
| Q4 25 | $2.9B | — | ||
| Q3 25 | $2.6B | — | ||
| Q2 25 | $2.6B | — | ||
| Q1 25 | $2.7B | — | ||
| Q4 24 | $1.7B | — | ||
| Q3 24 | $1.8B | — | ||
| Q2 24 | $1.9B | $4.8B | ||
| Q1 24 | $1.8B | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | ||
|---|---|---|
| Operating Cash FlowLast quarter | $-34.3M | — |
| Free Cash FlowOCF − Capex | $-36.6M | — |
| FCF MarginFCF / Revenue | -22.3% | — |
| Capex IntensityCapex / Revenue | 1.4% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $702.3M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-34.3M | — | ||
| Q3 25 | $-66.3M | — | ||
| Q2 25 | $-58.3M | — | ||
| Q1 25 | $870.1M | — | ||
| Q4 24 | $-30.0M | — | ||
| Q3 24 | $-77.0M | — | ||
| Q2 24 | $-71.5M | $155.1M | ||
| Q1 24 | $70.8M | — |
| Q4 25 | $-36.6M | — | ||
| Q3 25 | $-69.7M | — | ||
| Q2 25 | $-59.6M | — | ||
| Q1 25 | $868.4M | — | ||
| Q4 24 | $-33.8M | — | ||
| Q3 24 | $-77.5M | — | ||
| Q2 24 | $-78.8M | $153.8M | ||
| Q1 24 | $61.2M | — |
| Q4 25 | -22.3% | — | ||
| Q3 25 | -33.1% | — | ||
| Q2 25 | -33.3% | — | ||
| Q1 25 | 73.8% | — | ||
| Q4 24 | -15.8% | — | ||
| Q3 24 | -39.4% | — | ||
| Q2 24 | -42.2% | 92.4% | ||
| Q1 24 | 29.1% | — |
| Q4 25 | 1.4% | — | ||
| Q3 25 | 1.6% | — | ||
| Q2 25 | 0.7% | — | ||
| Q1 25 | 0.1% | — | ||
| Q4 24 | 1.8% | — | ||
| Q3 24 | 0.3% | — | ||
| Q2 24 | 4.0% | 0.8% | ||
| Q1 24 | 4.6% | — |
| Q4 25 | — | — | ||
| Q3 25 | -4.17× | — | ||
| Q2 25 | — | — | ||
| Q1 25 | 1.00× | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | 10.20× | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.