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Side-by-side financial comparison of Restaurant Brands International Inc. (QSR) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.0B vs $2.3B, roughly 1.3× Restaurant Brands International Inc.). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs 19.7%, a 14.9% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (7.8% vs 7.3%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (6.3% CAGR vs 4.3%).

Restaurant Brands International Inc. (RBI) is an American-Canadian multinational fast food holding company. It was formed in 2014 by the $12.5 billion merger between American fast food restaurant chain Burger King and Canadian coffee shop and restaurant chain Tim Hortons, and expanded by the purchases of Popeyes and Firehouse Subs in 2017 and 2021, respectively. The company is the fifth-largest operator of fast food restaurants in the world after Subway, McDonald's, Starbucks and Yum! Brands....

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

QSR vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.3× larger
VRTX
$3.0B
$2.3B
QSR
Growing faster (revenue YoY)
VRTX
VRTX
+0.5% gap
VRTX
7.8%
7.3%
QSR
Higher net margin
VRTX
VRTX
14.9% more per $
VRTX
34.5%
19.7%
QSR
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
6.3%
4.3%
QSR

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
QSR
QSR
VRTX
VRTX
Revenue
$2.3B
$3.0B
Net Profit
$445.0M
$1.0B
Gross Margin
86.8%
Operating Margin
0.0%
38.1%
Net Margin
19.7%
34.5%
Revenue YoY
7.3%
7.8%
Net Profit YoY
59.6%
EPS (diluted)
$0.97
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
QSR
QSR
VRTX
VRTX
Q1 26
$2.3B
$3.0B
Q4 25
$2.5B
$3.2B
Q3 25
$2.4B
$3.1B
Q2 25
$2.4B
$3.0B
Q1 25
$2.1B
$2.8B
Q4 24
$2.3B
$2.9B
Q3 24
$2.3B
$2.8B
Q2 24
$2.1B
$2.6B
Net Profit
QSR
QSR
VRTX
VRTX
Q1 26
$445.0M
$1.0B
Q4 25
$155.0M
$1.2B
Q3 25
$436.0M
$1.1B
Q2 25
$263.0M
$1.0B
Q1 25
$221.0M
$646.3M
Q4 24
$361.0M
$913.0M
Q3 24
$357.0M
$1.0B
Q2 24
$399.0M
$-3.6B
Gross Margin
QSR
QSR
VRTX
VRTX
Q1 26
86.8%
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
QSR
QSR
VRTX
VRTX
Q1 26
0.0%
38.1%
Q4 25
25.2%
37.8%
Q3 25
27.1%
38.6%
Q2 25
20.0%
38.8%
Q1 25
20.6%
22.7%
Q4 24
27.7%
35.2%
Q3 24
25.2%
40.3%
Q2 24
31.9%
-132.9%
Net Margin
QSR
QSR
VRTX
VRTX
Q1 26
19.7%
34.5%
Q4 25
6.3%
37.3%
Q3 25
17.8%
35.2%
Q2 25
10.9%
34.8%
Q1 25
10.5%
23.3%
Q4 24
15.7%
31.4%
Q3 24
15.6%
37.7%
Q2 24
19.2%
-135.8%
EPS (diluted)
QSR
QSR
VRTX
VRTX
Q1 26
$0.97
$4.02
Q4 25
$0.33
$4.64
Q3 25
$0.96
$4.20
Q2 25
$0.57
$3.99
Q1 25
$0.49
$2.49
Q4 24
$0.79
$3.62
Q3 24
$0.79
$4.01
Q2 24
$0.88
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
QSR
QSR
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$1.0B
Total DebtLower is stronger
$13.3B
Stockholders' EquityBook value
$5.3B
$19.4B
Total Assets
$24.9B
$26.5B
Debt / EquityLower = less leverage
2.51×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
QSR
QSR
VRTX
VRTX
Q1 26
$1.0B
Q4 25
$6.6B
Q3 25
$6.3B
Q2 25
$6.4B
Q1 25
$6.2B
Q4 24
$6.1B
Q3 24
$6.5B
Q2 24
$5.8B
Total Debt
QSR
QSR
VRTX
VRTX
Q1 26
$13.3B
Q4 25
$13.3B
Q3 25
$13.5B
Q2 25
$13.6B
Q1 25
$13.6B
Q4 24
$13.6B
Q3 24
$13.7B
Q2 24
$13.7B
Stockholders' Equity
QSR
QSR
VRTX
VRTX
Q1 26
$5.3B
$19.4B
Q4 25
$3.6B
$18.7B
Q3 25
$3.4B
$17.3B
Q2 25
$3.3B
$17.2B
Q1 25
$3.1B
$16.5B
Q4 24
$3.1B
$16.4B
Q3 24
$3.2B
$15.6B
Q2 24
$3.1B
$14.8B
Total Assets
QSR
QSR
VRTX
VRTX
Q1 26
$24.9B
$26.5B
Q4 25
$25.6B
$25.6B
Q3 25
$25.7B
$24.9B
Q2 25
$25.7B
$24.0B
Q1 25
$24.9B
$22.9B
Q4 24
$24.6B
$22.5B
Q3 24
$25.1B
$22.2B
Q2 24
$24.8B
$20.1B
Debt / Equity
QSR
QSR
VRTX
VRTX
Q1 26
2.51×
Q4 25
3.65×
Q3 25
3.99×
Q2 25
4.10×
Q1 25
4.37×
Q4 24
4.39×
Q3 24
4.22×
Q2 24
4.46×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
QSR
QSR
VRTX
VRTX
Operating Cash FlowLast quarter
$227.0M
Free Cash FlowOCF − Capex
$169.0M
FCF MarginFCF / Revenue
7.5%
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
0.51×
TTM Free Cash FlowTrailing 4 quarters
$1.6B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
QSR
QSR
VRTX
VRTX
Q1 26
$227.0M
Q4 25
$555.0M
$498.0M
Q3 25
$592.0M
$1.2B
Q2 25
$449.0M
$1.1B
Q1 25
$118.0M
$818.9M
Q4 24
$481.0M
$584.6M
Q3 24
$540.0M
$1.4B
Q2 24
$334.0M
$-3.8B
Free Cash Flow
QSR
QSR
VRTX
VRTX
Q1 26
$169.0M
Q4 25
$453.0M
$348.6M
Q3 25
$531.0M
$1.1B
Q2 25
$411.0M
$927.4M
Q1 25
$54.0M
$778.2M
Q4 24
$404.0M
$492.0M
Q3 24
$485.0M
$1.3B
Q2 24
$291.0M
$-3.8B
FCF Margin
QSR
QSR
VRTX
VRTX
Q1 26
7.5%
Q4 25
18.4%
10.9%
Q3 25
21.7%
37.0%
Q2 25
17.1%
31.3%
Q1 25
2.6%
28.1%
Q4 24
17.6%
16.9%
Q3 24
21.2%
47.0%
Q2 24
14.0%
-144.5%
Capex Intensity
QSR
QSR
VRTX
VRTX
Q1 26
Q4 25
4.1%
4.7%
Q3 25
2.5%
3.3%
Q2 25
1.6%
4.9%
Q1 25
3.0%
1.5%
Q4 24
3.4%
3.2%
Q3 24
2.4%
2.4%
Q2 24
2.1%
2.6%
Cash Conversion
QSR
QSR
VRTX
VRTX
Q1 26
0.51×
Q4 25
3.58×
0.42×
Q3 25
1.36×
1.15×
Q2 25
1.71×
1.04×
Q1 25
0.53×
1.27×
Q4 24
1.33×
0.64×
Q3 24
1.51×
1.31×
Q2 24
0.84×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

QSR
QSR

TH$997.0M44%
RH$448.0M20%
BK$365.0M16%
INTL$254.0M11%
PLK$190.0M8%
FHS$60.0M3%

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

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