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Side-by-side financial comparison of Q2 Holdings, Inc. (QTWO) and REPLIGEN CORP (RGEN). Click either name above to swap in a different company.

Q2 Holdings, Inc. is the larger business by last-quarter revenue ($216.5M vs $197.9M, roughly 1.1× REPLIGEN CORP). Q2 Holdings, Inc. runs the higher net margin — 12.3% vs 6.7%, a 5.6% gap on every dollar of revenue. On growth, Q2 Holdings, Inc. posted the faster year-over-year revenue change (14.1% vs 13.6%). Q2 Holdings, Inc. produced more free cash flow last quarter ($44.2M vs $17.6M). Over the past eight quarters, REPLIGEN CORP's revenue compounded faster (14.4% CAGR vs 11.9%).

Q2 Holdings, Inc. is a global financial technology firm that develops cloud-based digital banking platforms. It serves regional banks, credit unions, and other financial institutions, enabling them to offer secure online and mobile banking experiences to retail and business customers, with core operations based in North America.

Repligen Corporation is a global life sciences company devoted to the development and commercialization of innovative bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs.2025 The company is based in Waltham, Massachusetts,2014 and was incorporated in Delaware in 1981. A public company, Repligen is listed on the NASDAQ exchange under the symbol RGEN. As of 2025, Repligen employs over 1,900 employees globally and serves primarily biop...

QTWO vs RGEN — Head-to-Head

Bigger by revenue
QTWO
QTWO
1.1× larger
QTWO
$216.5M
$197.9M
RGEN
Growing faster (revenue YoY)
QTWO
QTWO
+0.5% gap
QTWO
14.1%
13.6%
RGEN
Higher net margin
QTWO
QTWO
5.6% more per $
QTWO
12.3%
6.7%
RGEN
More free cash flow
QTWO
QTWO
$26.7M more FCF
QTWO
$44.2M
$17.6M
RGEN
Faster 2-yr revenue CAGR
RGEN
RGEN
Annualised
RGEN
14.4%
11.9%
QTWO

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
QTWO
QTWO
RGEN
RGEN
Revenue
$216.5M
$197.9M
Net Profit
$26.6M
$13.3M
Gross Margin
59.1%
52.5%
Operating Margin
12.8%
9.0%
Net Margin
12.3%
6.7%
Revenue YoY
14.1%
13.6%
Net Profit YoY
460.5%
143.9%
EPS (diluted)
$0.40
$0.24

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
QTWO
QTWO
RGEN
RGEN
Q1 26
$216.5M
Q4 25
$208.2M
$197.9M
Q3 25
$201.7M
$188.8M
Q2 25
$195.1M
$182.4M
Q1 25
$189.7M
$169.2M
Q4 24
$183.0M
$174.1M
Q3 24
$175.0M
$154.9M
Q2 24
$172.9M
$154.1M
Net Profit
QTWO
QTWO
RGEN
RGEN
Q1 26
$26.6M
Q4 25
$20.4M
$13.3M
Q3 25
$15.0M
$14.9M
Q2 25
$11.8M
$14.9M
Q1 25
$4.8M
$5.8M
Q4 24
$164.0K
$-30.3M
Q3 24
$-11.8M
$-654.0K
Q2 24
$-13.1M
$3.3M
Gross Margin
QTWO
QTWO
RGEN
RGEN
Q1 26
59.1%
Q4 25
55.4%
52.5%
Q3 25
54.0%
53.2%
Q2 25
53.6%
50.0%
Q1 25
53.2%
53.6%
Q4 24
52.6%
26.1%
Q3 24
50.9%
50.0%
Q2 24
50.2%
49.8%
Operating Margin
QTWO
QTWO
RGEN
RGEN
Q1 26
12.8%
Q4 25
8.1%
9.0%
Q3 25
5.5%
8.9%
Q2 25
5.0%
7.6%
Q1 25
1.2%
3.9%
Q4 24
-0.9%
-17.7%
Q3 24
-7.3%
-5.1%
Q2 24
-7.9%
1.0%
Net Margin
QTWO
QTWO
RGEN
RGEN
Q1 26
12.3%
Q4 25
9.8%
6.7%
Q3 25
7.5%
7.9%
Q2 25
6.0%
8.2%
Q1 25
2.5%
3.4%
Q4 24
0.1%
-17.4%
Q3 24
-6.7%
-0.4%
Q2 24
-7.6%
2.2%
EPS (diluted)
QTWO
QTWO
RGEN
RGEN
Q1 26
$0.40
Q4 25
$0.32
$0.24
Q3 25
$0.23
$0.26
Q2 25
$0.18
$0.26
Q1 25
$0.07
$0.10
Q4 24
$0.01
$-0.55
Q3 24
$-0.20
$-0.01
Q2 24
$-0.22
$0.06

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
QTWO
QTWO
RGEN
RGEN
Cash + ST InvestmentsLiquidity on hand
$342.3M
$767.6M
Total DebtLower is stronger
$542.2M
Stockholders' EquityBook value
$611.7M
$2.1B
Total Assets
$1.2B
$2.9B
Debt / EquityLower = less leverage
0.26×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
QTWO
QTWO
RGEN
RGEN
Q1 26
$342.3M
Q4 25
$432.7M
$767.6M
Q3 25
$568.7M
$748.7M
Q2 25
$532.1M
$708.9M
Q1 25
$486.0M
$697.2M
Q4 24
$446.6M
$757.4M
Q3 24
$407.9M
$784.0M
Q2 24
$372.1M
$809.1M
Total Debt
QTWO
QTWO
RGEN
RGEN
Q1 26
Q4 25
$542.2M
Q3 25
$537.9M
Q2 25
Q1 25
Q4 24
$525.6M
Q3 24
Q2 24
Stockholders' Equity
QTWO
QTWO
RGEN
RGEN
Q1 26
$611.7M
Q4 25
$661.8M
$2.1B
Q3 25
$622.9M
$2.1B
Q2 25
$584.3M
$2.1B
Q1 25
$545.5M
$2.0B
Q4 24
$517.8M
$2.0B
Q3 24
$495.1M
$2.0B
Q2 24
$480.7M
$2.0B
Total Assets
QTWO
QTWO
RGEN
RGEN
Q1 26
$1.2B
Q4 25
$1.3B
$2.9B
Q3 25
$1.4B
$2.9B
Q2 25
$1.4B
$2.9B
Q1 25
$1.3B
$2.9B
Q4 24
$1.3B
$2.8B
Q3 24
$1.3B
$2.8B
Q2 24
$1.2B
$2.9B
Debt / Equity
QTWO
QTWO
RGEN
RGEN
Q1 26
Q4 25
0.26×
Q3 25
0.26×
Q2 25
Q1 25
Q4 24
0.27×
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
QTWO
QTWO
RGEN
RGEN
Operating Cash FlowLast quarter
$56.3M
$25.7M
Free Cash FlowOCF − Capex
$44.2M
$17.6M
FCF MarginFCF / Revenue
20.4%
8.9%
Capex IntensityCapex / Revenue
4.1%
Cash ConversionOCF / Net Profit
2.11×
1.93×
TTM Free Cash FlowTrailing 4 quarters
$196.1M
$93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
QTWO
QTWO
RGEN
RGEN
Q1 26
$56.3M
Q4 25
$63.7M
$25.7M
Q3 25
$45.6M
$48.1M
Q2 25
$48.6M
$28.6M
Q1 25
$43.5M
$15.0M
Q4 24
$43.0M
$39.2M
Q3 24
$43.3M
$49.3M
Q2 24
$36.0M
$42.2M
Free Cash Flow
QTWO
QTWO
RGEN
RGEN
Q1 26
$44.2M
Q4 25
$61.7M
$17.6M
Q3 25
$42.9M
$43.4M
Q2 25
$47.3M
$21.5M
Q1 25
$42.7M
$11.4M
Q4 24
$41.6M
$33.6M
Q3 24
$40.9M
$42.3M
Q2 24
$34.6M
$37.4M
FCF Margin
QTWO
QTWO
RGEN
RGEN
Q1 26
20.4%
Q4 25
29.6%
8.9%
Q3 25
21.3%
23.0%
Q2 25
24.3%
11.8%
Q1 25
22.5%
6.8%
Q4 24
22.7%
19.3%
Q3 24
23.3%
27.3%
Q2 24
20.0%
24.3%
Capex Intensity
QTWO
QTWO
RGEN
RGEN
Q1 26
Q4 25
1.0%
4.1%
Q3 25
1.3%
2.5%
Q2 25
0.7%
3.9%
Q1 25
0.4%
2.1%
Q4 24
0.8%
3.2%
Q3 24
1.4%
4.5%
Q2 24
0.8%
3.1%
Cash Conversion
QTWO
QTWO
RGEN
RGEN
Q1 26
2.11×
Q4 25
3.12×
1.93×
Q3 25
3.03×
3.23×
Q2 25
4.13×
1.92×
Q1 25
9.16×
2.57×
Q4 24
262.41×
Q3 24
Q2 24
12.70×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

QTWO
QTWO

Subscription$179.9M83%
Services and Other$18.8M9%
Transactional$17.8M8%

RGEN
RGEN

Segment breakdown not available.

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