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Side-by-side financial comparison of Ultragenyx Pharmaceutical Inc. (RARE) and VIRTUS INVESTMENT PARTNERS, INC. (VRTS). Click either name above to swap in a different company.

VIRTUS INVESTMENT PARTNERS, INC. is the larger business by last-quarter revenue ($208.0M vs $207.3M, roughly 1.0× Ultragenyx Pharmaceutical Inc.). VIRTUS INVESTMENT PARTNERS, INC. runs the higher net margin — 16.3% vs -62.0%, a 78.3% gap on every dollar of revenue. On growth, Ultragenyx Pharmaceutical Inc. posted the faster year-over-year revenue change (25.9% vs -10.9%). VIRTUS INVESTMENT PARTNERS, INC. produced more free cash flow last quarter ($-74.1M vs $-100.8M). Over the past eight quarters, Ultragenyx Pharmaceutical Inc.'s revenue compounded faster (38.0% CAGR vs -3.2%).

Ultragenyx Pharmaceutical Inc. is an American biopharmaceutical company involved in the research and development of novel products for treatment of rare and ultra-rare genetic diseases for which there are typically no approved treatments and high unmet medical need. The company works with multiple drug modalities including biologics, small molecule, gene therapies, and ASO and mRNAs in the disease categories of bone, endocrine, metabolic, muscle and CNS diseases.

Virtus Investment Partners, Inc. is an American company which operates as a multi-manager asset management business, comprising a number of individual affiliated managers, each having its own investment process and brand, and the services of unaffiliated sub advisers.

RARE vs VRTS — Head-to-Head

Bigger by revenue
VRTS
VRTS
1.0× larger
VRTS
$208.0M
$207.3M
RARE
Growing faster (revenue YoY)
RARE
RARE
+36.8% gap
RARE
25.9%
-10.9%
VRTS
Higher net margin
VRTS
VRTS
78.3% more per $
VRTS
16.3%
-62.0%
RARE
More free cash flow
VRTS
VRTS
$26.7M more FCF
VRTS
$-74.1M
$-100.8M
RARE
Faster 2-yr revenue CAGR
RARE
RARE
Annualised
RARE
38.0%
-3.2%
VRTS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
RARE
RARE
VRTS
VRTS
Revenue
$207.3M
$208.0M
Net Profit
$-128.6M
$33.9M
Gross Margin
Operating Margin
-54.7%
19.1%
Net Margin
-62.0%
16.3%
Revenue YoY
25.9%
-10.9%
Net Profit YoY
3.5%
-14.2%
EPS (diluted)
$-1.28
$5.15

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RARE
RARE
VRTS
VRTS
Q4 25
$207.3M
$208.0M
Q3 25
$159.9M
$216.4M
Q2 25
$166.5M
$210.5M
Q1 25
$139.3M
$217.9M
Q4 24
$164.6M
$233.5M
Q3 24
$139.5M
$227.0M
Q2 24
$147.0M
$224.4M
Q1 24
$108.8M
$222.0M
Net Profit
RARE
RARE
VRTS
VRTS
Q4 25
$-128.6M
$33.9M
Q3 25
$-180.4M
$31.3M
Q2 25
$-115.0M
$42.7M
Q1 25
$-151.1M
$28.1M
Q4 24
$-133.2M
$39.5M
Q3 24
$-133.5M
$49.1M
Q2 24
$-131.6M
$26.0M
Q1 24
$-170.7M
$37.9M
Operating Margin
RARE
RARE
VRTS
VRTS
Q4 25
-54.7%
19.1%
Q3 25
-106.9%
21.7%
Q2 25
-64.8%
21.5%
Q1 25
-102.6%
16.8%
Q4 24
-74.3%
21.7%
Q3 24
-94.6%
24.3%
Q2 24
-79.1%
19.7%
Q1 24
-151.9%
14.5%
Net Margin
RARE
RARE
VRTS
VRTS
Q4 25
-62.0%
16.3%
Q3 25
-112.8%
14.5%
Q2 25
-69.0%
20.3%
Q1 25
-108.5%
12.9%
Q4 24
-80.9%
16.9%
Q3 24
-95.7%
21.6%
Q2 24
-89.5%
11.6%
Q1 24
-156.8%
17.1%
EPS (diluted)
RARE
RARE
VRTS
VRTS
Q4 25
$-1.28
$5.15
Q3 25
$-1.81
$4.65
Q2 25
$-1.17
$6.12
Q1 25
$-1.57
$4.05
Q4 24
$-1.34
$4.65
Q3 24
$-1.40
$5.71
Q2 24
$-1.52
$2.43
Q1 24
$-2.03
$4.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RARE
RARE
VRTS
VRTS
Cash + ST InvestmentsLiquidity on hand
$421.0M
Total DebtLower is stronger
$390.0M
Stockholders' EquityBook value
$-80.0M
$934.0M
Total Assets
$1.5B
$4.3B
Debt / EquityLower = less leverage
0.42×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RARE
RARE
VRTS
VRTS
Q4 25
$421.0M
Q3 25
$202.5M
Q2 25
$176.3M
Q1 25
$127.1M
Q4 24
$174.0M
Q3 24
$150.6M
Q2 24
$480.7M
Q1 24
$112.3M
Total Debt
RARE
RARE
VRTS
VRTS
Q4 25
$390.0M
Q3 25
$390.6M
Q2 25
$231.3M
Q1 25
$231.7M
Q4 24
$232.1M
Q3 24
$237.5M
Q2 24
$247.6M
Q1 24
$253.0M
Stockholders' Equity
RARE
RARE
VRTS
VRTS
Q4 25
$-80.0M
$934.0M
Q3 25
$9.2M
$918.7M
Q2 25
$151.3M
$896.4M
Q1 25
$144.2M
$893.7M
Q4 24
$255.0M
$897.5M
Q3 24
$346.8M
$889.0M
Q2 24
$432.4M
$868.7M
Q1 24
$140.3M
$871.7M
Total Assets
RARE
RARE
VRTS
VRTS
Q4 25
$1.5B
$4.3B
Q3 25
$1.2B
$3.9B
Q2 25
$1.3B
$3.7B
Q1 25
$1.3B
$3.7B
Q4 24
$1.5B
$4.0B
Q3 24
$1.5B
$3.6B
Q2 24
$1.6B
$3.6B
Q1 24
$1.3B
$3.5B
Debt / Equity
RARE
RARE
VRTS
VRTS
Q4 25
0.42×
Q3 25
0.43×
Q2 25
0.26×
Q1 25
0.26×
Q4 24
0.26×
Q3 24
0.27×
Q2 24
0.29×
Q1 24
0.29×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
RARE
RARE
VRTS
VRTS
Operating Cash FlowLast quarter
$-99.8M
$-67.2M
Free Cash FlowOCF − Capex
$-100.8M
$-74.1M
FCF MarginFCF / Revenue
-48.6%
-35.6%
Capex IntensityCapex / Revenue
0.5%
3.3%
Cash ConversionOCF / Net Profit
-1.99×
TTM Free Cash FlowTrailing 4 quarters
$-472.0M
$100.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
RARE
RARE
VRTS
VRTS
Q4 25
$-99.8M
$-67.2M
Q3 25
$-91.4M
$108.3M
Q2 25
$-108.3M
$75.8M
Q1 25
$-166.5M
$-3.8M
Q4 24
$-79.3M
$1.8M
Q3 24
$-67.0M
$69.1M
Q2 24
$-77.0M
$70.0M
Q1 24
$-190.7M
$-34.5M
Free Cash Flow
RARE
RARE
VRTS
VRTS
Q4 25
$-100.8M
$-74.1M
Q3 25
$-92.7M
$106.9M
Q2 25
$-110.7M
$74.2M
Q1 25
$-167.8M
$-6.8M
Q4 24
$-79.5M
$-3.8M
Q3 24
$-68.6M
$68.7M
Q2 24
$-79.0M
$68.6M
Q1 24
$-193.9M
$-36.5M
FCF Margin
RARE
RARE
VRTS
VRTS
Q4 25
-48.6%
-35.6%
Q3 25
-58.0%
49.4%
Q2 25
-66.5%
35.2%
Q1 25
-120.5%
-3.1%
Q4 24
-48.3%
-1.6%
Q3 24
-49.2%
30.3%
Q2 24
-53.7%
30.6%
Q1 24
-178.2%
-16.4%
Capex Intensity
RARE
RARE
VRTS
VRTS
Q4 25
0.5%
3.3%
Q3 25
0.8%
0.7%
Q2 25
1.5%
0.7%
Q1 25
1.0%
1.4%
Q4 24
0.1%
2.4%
Q3 24
1.2%
0.2%
Q2 24
1.4%
0.6%
Q1 24
3.0%
0.9%
Cash Conversion
RARE
RARE
VRTS
VRTS
Q4 25
-1.99×
Q3 25
3.45×
Q2 25
1.77×
Q1 25
-0.13×
Q4 24
0.04×
Q3 24
1.41×
Q2 24
2.69×
Q1 24
-0.91×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

RARE
RARE

Royalty$105.6M51%
Products$101.7M49%

VRTS
VRTS

Open End Funds$68.9M33%
Retail Separate Accounts$51.3M25%
Institutional Accounts$39.6M19%
Administration And Shareholder Service Fees$18.4M9%
Closed End Funds$15.9M8%
Distribution And Service Fees$12.3M6%

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