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Side-by-side financial comparison of Regions Financial Corporation (RF) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.0B vs $1.9B, roughly 1.6× Regions Financial Corporation). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs 29.8%, a 4.7% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (7.8% vs 5.0%). Over the past eight quarters, Regions Financial Corporation's revenue compounded faster (25.7% CAGR vs 6.3%).

Regions Financial Corporation is an American bank holding company headquartered in the Regions Center in Birmingham, Alabama. The company provides retail and commercial banking, trust, stock brokerage, and mortgage services. Its banking subsidiary, Regions Bank, operates about 2,000 automated teller machines and 1,300 branches in 15 states in the Southern and Midwestern United States.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

RF vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.6× larger
VRTX
$3.0B
$1.9B
RF
Growing faster (revenue YoY)
VRTX
VRTX
+2.8% gap
VRTX
7.8%
5.0%
RF
Higher net margin
VRTX
VRTX
4.7% more per $
VRTX
34.5%
29.8%
RF
Faster 2-yr revenue CAGR
RF
RF
Annualised
RF
25.7%
6.3%
VRTX

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
RF
RF
VRTX
VRTX
Revenue
$1.9B
$3.0B
Net Profit
$559.0M
$1.0B
Gross Margin
86.8%
Operating Margin
38.1%
Net Margin
29.8%
34.5%
Revenue YoY
5.0%
7.8%
Net Profit YoY
59.6%
EPS (diluted)
$0.62
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RF
RF
VRTX
VRTX
Q1 26
$1.9B
$3.0B
Q4 25
$1.3B
$3.2B
Q3 25
$1.3B
$3.1B
Q2 25
$1.3B
$3.0B
Q1 25
$1.2B
$2.8B
Q4 24
$1.2B
$2.9B
Q3 24
$1.2B
$2.8B
Q2 24
$1.2B
$2.6B
Net Profit
RF
RF
VRTX
VRTX
Q1 26
$559.0M
$1.0B
Q4 25
$534.0M
$1.2B
Q3 25
$569.0M
$1.1B
Q2 25
$563.0M
$1.0B
Q1 25
$490.0M
$646.3M
Q4 24
$534.0M
$913.0M
Q3 24
$490.0M
$1.0B
Q2 24
$501.0M
$-3.6B
Gross Margin
RF
RF
VRTX
VRTX
Q1 26
86.8%
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
RF
RF
VRTX
VRTX
Q1 26
38.1%
Q4 25
55.3%
37.8%
Q3 25
56.3%
38.6%
Q2 25
56.1%
38.8%
Q1 25
52.0%
22.7%
Q4 24
53.4%
35.2%
Q3 24
49.9%
40.3%
Q2 24
52.7%
-132.9%
Net Margin
RF
RF
VRTX
VRTX
Q1 26
29.8%
34.5%
Q4 25
41.7%
37.3%
Q3 25
45.3%
35.2%
Q2 25
44.7%
34.8%
Q1 25
41.0%
23.3%
Q4 24
43.4%
31.4%
Q3 24
40.2%
37.7%
Q2 24
42.2%
-135.8%
EPS (diluted)
RF
RF
VRTX
VRTX
Q1 26
$0.62
$4.02
Q4 25
$0.59
$4.64
Q3 25
$0.61
$4.20
Q2 25
$0.59
$3.99
Q1 25
$0.51
$2.49
Q4 24
$0.55
$3.62
Q3 24
$0.49
$4.01
Q2 24
$0.52
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RF
RF
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
Total DebtLower is stronger
$6.3B
Stockholders' EquityBook value
$18.8B
$19.4B
Total Assets
$160.7B
$26.5B
Debt / EquityLower = less leverage
0.34×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RF
RF
VRTX
VRTX
Q1 26
Q4 25
$6.6B
Q3 25
$6.3B
Q2 25
$6.4B
Q1 25
$6.2B
Q4 24
$6.1B
Q3 24
$6.5B
Q2 24
$5.8B
Total Debt
RF
RF
VRTX
VRTX
Q1 26
$6.3B
Q4 25
$4.1B
Q3 25
$4.8B
Q2 25
$5.3B
Q1 25
$6.0B
Q4 24
$6.0B
Q3 24
$6.0B
Q2 24
$5.1B
Stockholders' Equity
RF
RF
VRTX
VRTX
Q1 26
$18.8B
$19.4B
Q4 25
$19.0B
$18.7B
Q3 25
$19.0B
$17.3B
Q2 25
$18.7B
$17.2B
Q1 25
$18.5B
$16.5B
Q4 24
$17.9B
$16.4B
Q3 24
$18.7B
$15.6B
Q2 24
$17.2B
$14.8B
Total Assets
RF
RF
VRTX
VRTX
Q1 26
$160.7B
$26.5B
Q4 25
$158.8B
$25.6B
Q3 25
$159.9B
$24.9B
Q2 25
$159.2B
$24.0B
Q1 25
$159.8B
$22.9B
Q4 24
$157.3B
$22.5B
Q3 24
$157.4B
$22.2B
Q2 24
$154.1B
$20.1B
Debt / Equity
RF
RF
VRTX
VRTX
Q1 26
0.34×
Q4 25
0.22×
Q3 25
0.25×
Q2 25
0.28×
Q1 25
0.32×
Q4 24
0.34×
Q3 24
0.32×
Q2 24
0.30×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

RF
RF

Segment breakdown not available.

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

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