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Side-by-side financial comparison of REPLIGEN CORP (RGEN) and SAFETY INSURANCE GROUP INC (SAFT). Click either name above to swap in a different company.

SAFETY INSURANCE GROUP INC is the larger business by last-quarter revenue ($319.3M vs $197.9M, roughly 1.6× REPLIGEN CORP). REPLIGEN CORP runs the higher net margin — 6.7% vs 6.3%, a 0.4% gap on every dollar of revenue. On growth, REPLIGEN CORP posted the faster year-over-year revenue change (13.6% vs 11.4%). SAFETY INSURANCE GROUP INC produced more free cash flow last quarter ($192.0M vs $17.6M). Over the past eight quarters, REPLIGEN CORP's revenue compounded faster (14.4% CAGR vs 9.1%).

Repligen Corporation is a global life sciences company devoted to the development and commercialization of innovative bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs.2025 The company is based in Waltham, Massachusetts,2014 and was incorporated in Delaware in 1981. A public company, Repligen is listed on the NASDAQ exchange under the symbol RGEN. As of 2025, Repligen employs over 1,900 employees globally and serves primarily biop...

Nationwide Mutual Insurance Company and affiliated companies, commonly shortened to Nationwide, is a group of large U.S. insurance and financial services companies based in Columbus, Ohio. The company also operates regional headquarters in Scottsdale, Arizona and Des Moines, Iowa. Nationwide currently has approximately 24,000 employees, and is ranked No. 72 in the 2025 Fortune 500 list.

RGEN vs SAFT — Head-to-Head

Bigger by revenue
SAFT
SAFT
1.6× larger
SAFT
$319.3M
$197.9M
RGEN
Growing faster (revenue YoY)
RGEN
RGEN
+2.3% gap
RGEN
13.6%
11.4%
SAFT
Higher net margin
RGEN
RGEN
0.4% more per $
RGEN
6.7%
6.3%
SAFT
More free cash flow
SAFT
SAFT
$174.4M more FCF
SAFT
$192.0M
$17.6M
RGEN
Faster 2-yr revenue CAGR
RGEN
RGEN
Annualised
RGEN
14.4%
9.1%
SAFT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
RGEN
RGEN
SAFT
SAFT
Revenue
$197.9M
$319.3M
Net Profit
$13.3M
$20.1M
Gross Margin
52.5%
Operating Margin
9.0%
8.0%
Net Margin
6.7%
6.3%
Revenue YoY
13.6%
11.4%
Net Profit YoY
143.9%
147.3%
EPS (diluted)
$0.24
$1.36

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RGEN
RGEN
SAFT
SAFT
Q4 25
$197.9M
$319.3M
Q3 25
$188.8M
$326.6M
Q2 25
$182.4M
$316.3M
Q1 25
$169.2M
$301.4M
Q4 24
$174.1M
$286.7M
Q3 24
$154.9M
$295.3M
Q2 24
$154.1M
$269.8M
Q1 24
$151.3M
$268.2M
Net Profit
RGEN
RGEN
SAFT
SAFT
Q4 25
$13.3M
$20.1M
Q3 25
$14.9M
$28.3M
Q2 25
$14.9M
$28.9M
Q1 25
$5.8M
$21.9M
Q4 24
$-30.3M
$8.1M
Q3 24
$-654.0K
$25.9M
Q2 24
$3.3M
$16.6M
Q1 24
$2.1M
$20.1M
Gross Margin
RGEN
RGEN
SAFT
SAFT
Q4 25
52.5%
Q3 25
53.2%
Q2 25
50.0%
Q1 25
53.6%
Q4 24
26.1%
Q3 24
50.0%
Q2 24
49.8%
Q1 24
49.5%
Operating Margin
RGEN
RGEN
SAFT
SAFT
Q4 25
9.0%
8.0%
Q3 25
8.9%
11.1%
Q2 25
7.6%
11.6%
Q1 25
3.9%
9.4%
Q4 24
-17.7%
3.5%
Q3 24
-5.1%
11.1%
Q2 24
1.0%
7.9%
Q1 24
1.3%
9.5%
Net Margin
RGEN
RGEN
SAFT
SAFT
Q4 25
6.7%
6.3%
Q3 25
7.9%
8.7%
Q2 25
8.2%
9.1%
Q1 25
3.4%
7.3%
Q4 24
-17.4%
2.8%
Q3 24
-0.4%
8.8%
Q2 24
2.2%
6.2%
Q1 24
1.4%
7.5%
EPS (diluted)
RGEN
RGEN
SAFT
SAFT
Q4 25
$0.24
$1.36
Q3 25
$0.26
$1.91
Q2 25
$0.26
$1.95
Q1 25
$0.10
$1.48
Q4 24
$-0.55
$0.56
Q3 24
$-0.01
$1.73
Q2 24
$0.06
$1.13
Q1 24
$0.04
$1.36

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RGEN
RGEN
SAFT
SAFT
Cash + ST InvestmentsLiquidity on hand
$767.6M
$73.9M
Total DebtLower is stronger
$542.2M
$50.0M
Stockholders' EquityBook value
$2.1B
$892.3M
Total Assets
$2.9B
$2.5B
Debt / EquityLower = less leverage
0.26×
0.06×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RGEN
RGEN
SAFT
SAFT
Q4 25
$767.6M
$73.9M
Q3 25
$748.7M
$56.2M
Q2 25
$708.9M
$49.4M
Q1 25
$697.2M
$64.7M
Q4 24
$757.4M
$59.0M
Q3 24
$784.0M
$82.3M
Q2 24
$809.1M
$44.6M
Q1 24
$780.6M
$30.8M
Total Debt
RGEN
RGEN
SAFT
SAFT
Q4 25
$542.2M
$50.0M
Q3 25
$537.9M
$30.0M
Q2 25
$30.0M
Q1 25
$30.0M
Q4 24
$525.6M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
RGEN
RGEN
SAFT
SAFT
Q4 25
$2.1B
$892.3M
Q3 25
$2.1B
$899.6M
Q2 25
$2.1B
$873.3M
Q1 25
$2.0B
$850.7M
Q4 24
$2.0B
$828.5M
Q3 24
$2.0B
$851.4M
Q2 24
$2.0B
$810.2M
Q1 24
$2.0B
$807.1M
Total Assets
RGEN
RGEN
SAFT
SAFT
Q4 25
$2.9B
$2.5B
Q3 25
$2.9B
$2.4B
Q2 25
$2.9B
$2.4B
Q1 25
$2.9B
$2.3B
Q4 24
$2.8B
$2.3B
Q3 24
$2.8B
$2.3B
Q2 24
$2.9B
$2.2B
Q1 24
$2.8B
$2.1B
Debt / Equity
RGEN
RGEN
SAFT
SAFT
Q4 25
0.26×
0.06×
Q3 25
0.26×
0.03×
Q2 25
0.03×
Q1 25
0.04×
Q4 24
0.27×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
RGEN
RGEN
SAFT
SAFT
Operating Cash FlowLast quarter
$25.7M
$194.5M
Free Cash FlowOCF − Capex
$17.6M
$192.0M
FCF MarginFCF / Revenue
8.9%
60.1%
Capex IntensityCapex / Revenue
4.1%
0.8%
Cash ConversionOCF / Net Profit
1.93×
9.67×
TTM Free Cash FlowTrailing 4 quarters
$93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
RGEN
RGEN
SAFT
SAFT
Q4 25
$25.7M
$194.5M
Q3 25
$48.1M
$85.5M
Q2 25
$28.6M
$32.3M
Q1 25
$15.0M
$3.2M
Q4 24
$39.2M
$128.7M
Q3 24
$49.3M
$73.8M
Q2 24
$42.2M
$25.6M
Q1 24
$44.7M
$-21.1M
Free Cash Flow
RGEN
RGEN
SAFT
SAFT
Q4 25
$17.6M
$192.0M
Q3 25
$43.4M
Q2 25
$21.5M
$32.3M
Q1 25
$11.4M
$2.8M
Q4 24
$33.6M
$124.3M
Q3 24
$42.3M
$73.2M
Q2 24
$37.4M
$25.0M
Q1 24
$36.4M
$-24.2M
FCF Margin
RGEN
RGEN
SAFT
SAFT
Q4 25
8.9%
60.1%
Q3 25
23.0%
Q2 25
11.8%
10.2%
Q1 25
6.8%
0.9%
Q4 24
19.3%
43.4%
Q3 24
27.3%
24.8%
Q2 24
24.3%
9.3%
Q1 24
24.0%
-9.0%
Capex Intensity
RGEN
RGEN
SAFT
SAFT
Q4 25
4.1%
0.8%
Q3 25
2.5%
0.0%
Q2 25
3.9%
0.0%
Q1 25
2.1%
0.1%
Q4 24
3.2%
1.5%
Q3 24
4.5%
0.2%
Q2 24
3.1%
0.2%
Q1 24
5.5%
1.1%
Cash Conversion
RGEN
RGEN
SAFT
SAFT
Q4 25
1.93×
9.67×
Q3 25
3.23×
3.02×
Q2 25
1.92×
1.12×
Q1 25
2.57×
0.14×
Q4 24
15.83×
Q3 24
2.85×
Q2 24
12.70×
1.54×
Q1 24
21.35×
-1.05×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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