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Side-by-side financial comparison of RIGEL PHARMACEUTICALS INC (RIGL) and STEM, INC. (STEM). Click either name above to swap in a different company.

RIGEL PHARMACEUTICALS INC is the larger business by last-quarter revenue ($69.8M vs $47.1M, roughly 1.5× STEM, INC.). RIGEL PHARMACEUTICALS INC runs the higher net margin — 384.0% vs -33.9%, a 417.9% gap on every dollar of revenue. On growth, RIGEL PHARMACEUTICALS INC posted the faster year-over-year revenue change (21.2% vs -15.6%). Over the past eight quarters, RIGEL PHARMACEUTICALS INC's revenue compounded faster (53.7% CAGR vs 36.1%).

Rigel Pharmaceuticals Inc is a clinical-stage biotechnology company focused on developing and commercializing targeted small molecule therapies for autoimmune, inflammatory, and hematologic diseases. Its approved flagship product treats adult immune thrombocytopenia, with primary operations and core markets in the United States, addressing unmet medical needs for underserved patient groups.

StemCells, Inc. is a public biopharmaceutical company headquartered in Newark, California, that is developing purified human neural stem cells (HuCNS-SCs) in the hopes of treating central nervous system disorders and paralysis. StemCells' HuCNS-SCs have the ability to differentiate into the three main types of cells found in the central nervous system: neurons, astrocytes and oligodendrocytes.

RIGL vs STEM — Head-to-Head

Bigger by revenue
RIGL
RIGL
1.5× larger
RIGL
$69.8M
$47.1M
STEM
Growing faster (revenue YoY)
RIGL
RIGL
+36.7% gap
RIGL
21.2%
-15.6%
STEM
Higher net margin
RIGL
RIGL
417.9% more per $
RIGL
384.0%
-33.9%
STEM
Faster 2-yr revenue CAGR
RIGL
RIGL
Annualised
RIGL
53.7%
36.1%
STEM

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
RIGL
RIGL
STEM
STEM
Revenue
$69.8M
$47.1M
Net Profit
$268.1M
$-16.0M
Gross Margin
91.5%
48.9%
Operating Margin
33.2%
-17.7%
Net Margin
384.0%
-33.9%
Revenue YoY
21.2%
-15.6%
Net Profit YoY
1769.2%
68.8%
EPS (diluted)
$14.11
$-4.40

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RIGL
RIGL
STEM
STEM
Q4 25
$69.8M
$47.1M
Q3 25
$69.5M
$38.2M
Q2 25
$101.7M
$38.4M
Q1 25
$53.3M
$32.5M
Q4 24
$57.6M
$55.8M
Q3 24
$55.3M
$29.3M
Q2 24
$36.8M
$34.0M
Q1 24
$29.5M
$25.5M
Net Profit
RIGL
RIGL
STEM
STEM
Q4 25
$268.1M
$-16.0M
Q3 25
$27.9M
$-23.8M
Q2 25
$59.6M
$202.5M
Q1 25
$11.4M
$-25.0M
Q4 24
$14.3M
$-51.1M
Q3 24
$12.4M
$-148.3M
Q2 24
$-1.0M
$-582.3M
Q1 24
$-8.2M
$-72.3M
Gross Margin
RIGL
RIGL
STEM
STEM
Q4 25
91.5%
48.9%
Q3 25
93.2%
35.5%
Q2 25
95.6%
33.4%
Q1 25
91.7%
32.4%
Q4 24
89.9%
-4.4%
Q3 24
85.5%
21.2%
Q2 24
92.4%
27.6%
Q1 24
93.1%
-95.0%
Operating Margin
RIGL
RIGL
STEM
STEM
Q4 25
33.2%
-17.7%
Q3 25
40.9%
-33.6%
Q2 25
60.1%
-34.8%
Q1 25
23.9%
-65.0%
Q4 24
28.9%
-84.4%
Q3 24
25.4%
-493.2%
Q2 24
1.2%
-1705.5%
Q1 24
-23.6%
-267.0%
Net Margin
RIGL
RIGL
STEM
STEM
Q4 25
384.0%
-33.9%
Q3 25
40.2%
-62.2%
Q2 25
58.6%
527.8%
Q1 25
21.5%
-76.9%
Q4 24
24.9%
-91.6%
Q3 24
22.5%
-506.3%
Q2 24
-2.8%
-1712.6%
Q1 24
-27.9%
-283.9%
EPS (diluted)
RIGL
RIGL
STEM
STEM
Q4 25
$14.11
$-4.40
Q3 25
$1.46
$-2.84
Q2 25
$3.28
$-1.79
Q1 25
$0.63
$-0.15
Q4 24
$0.82
$-15.29
Q3 24
$0.70
$-18.24
Q2 24
$-0.06
$-71.81
Q1 24
$-0.47
$-0.46

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RIGL
RIGL
STEM
STEM
Cash + ST InvestmentsLiquidity on hand
$155.0M
$48.9M
Total DebtLower is stronger
$52.5M
Stockholders' EquityBook value
$391.5M
$-249.4M
Total Assets
$513.6M
$308.9M
Debt / EquityLower = less leverage
0.13×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RIGL
RIGL
STEM
STEM
Q4 25
$155.0M
$48.9M
Q3 25
$137.1M
$43.1M
Q2 25
$108.4M
$40.8M
Q1 25
$77.1M
$58.6M
Q4 24
$77.3M
$56.3M
Q3 24
$61.1M
$75.4M
Q2 24
$49.1M
$89.6M
Q1 24
$49.5M
$112.8M
Total Debt
RIGL
RIGL
STEM
STEM
Q4 25
$52.5M
Q3 25
$60.0M
Q2 25
$60.0M
Q1 25
$60.0M
Q4 24
$60.0M
Q3 24
$60.0M
Q2 24
$60.0M
Q1 24
$60.0M
Stockholders' Equity
RIGL
RIGL
STEM
STEM
Q4 25
$391.5M
$-249.4M
Q3 25
$117.6M
$-235.7M
Q2 25
$81.9M
$-214.1M
Q1 25
$18.6M
$-417.5M
Q4 24
$3.3M
$-398.4M
Q3 24
$-14.6M
$-344.1M
Q2 24
$-29.9M
$-203.2M
Q1 24
$-31.7M
$371.6M
Total Assets
RIGL
RIGL
STEM
STEM
Q4 25
$513.6M
$308.9M
Q3 25
$242.5M
$362.6M
Q2 25
$206.7M
$379.2M
Q1 25
$176.0M
$405.1M
Q4 24
$164.0M
$437.4M
Q3 24
$139.4M
$537.8M
Q2 24
$128.4M
$691.5M
Q1 24
$126.5M
$1.3B
Debt / Equity
RIGL
RIGL
STEM
STEM
Q4 25
0.13×
Q3 25
0.51×
Q2 25
0.73×
Q1 25
3.23×
Q4 24
18.25×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
RIGL
RIGL
STEM
STEM
Operating Cash FlowLast quarter
$22.0M
$8.2M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
0.08×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
RIGL
RIGL
STEM
STEM
Q4 25
$22.0M
$8.2M
Q3 25
$24.0M
$11.4M
Q2 25
$30.5M
$-21.3M
Q1 25
$-893.0K
$8.5M
Q4 24
$14.5M
$-14.7M
Q3 24
$21.7M
$-9.4M
Q2 24
$302.0K
$-11.9M
Q1 24
$-5.0M
$-621.0K
Cash Conversion
RIGL
RIGL
STEM
STEM
Q4 25
0.08×
Q3 25
0.86×
Q2 25
0.51×
-0.11×
Q1 25
-0.08×
Q4 24
1.01×
Q3 24
1.75×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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