vs

Side-by-side financial comparison of Raymond James Financial (RJF) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Raymond James Financial is the larger business by last-quarter revenue ($3.9B vs $3.0B, roughly 1.3× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs 14.1%, a 20.4% gap on every dollar of revenue. On growth, Raymond James Financial posted the faster year-over-year revenue change (13.0% vs 7.8%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (6.3% CAGR vs 1.3%).

Raymond James Financial, Inc. is an American multinational independent investment bank and financial services company providing financial services to individuals, corporations, and municipalities through its subsidiary companies that engage primarily in investment and financial planning, in addition to investment banking and asset management. The company is headquartered in St. Petersburg, Florida.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

RJF vs VRTX — Head-to-Head

Bigger by revenue
RJF
RJF
1.3× larger
RJF
$3.9B
$3.0B
VRTX
Growing faster (revenue YoY)
RJF
RJF
+5.2% gap
RJF
13.0%
7.8%
VRTX
Higher net margin
VRTX
VRTX
20.4% more per $
VRTX
34.5%
14.1%
RJF
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
6.3%
1.3%
RJF

Income Statement — Q2 FY2026 vs Q1 FY2026

Metric
RJF
RJF
VRTX
VRTX
Revenue
$3.9B
$3.0B
Net Profit
$544.0M
$1.0B
Gross Margin
86.8%
Operating Margin
38.1%
Net Margin
14.1%
34.5%
Revenue YoY
13.0%
7.8%
Net Profit YoY
10.0%
59.6%
EPS (diluted)
$2.83
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RJF
RJF
VRTX
VRTX
Q1 26
$3.9B
$3.0B
Q4 25
$4.2B
$3.2B
Q3 25
$4.2B
$3.1B
Q2 25
$3.8B
$3.0B
Q1 25
$3.8B
$2.8B
Q4 24
$4.0B
$2.9B
Q3 24
$4.0B
$2.8B
Q2 24
$3.8B
$2.6B
Net Profit
RJF
RJF
VRTX
VRTX
Q1 26
$544.0M
$1.0B
Q4 25
$563.0M
$1.2B
Q3 25
$604.0M
$1.1B
Q2 25
$436.0M
$1.0B
Q1 25
$495.0M
$646.3M
Q4 24
$600.0M
$913.0M
Q3 24
$602.0M
$1.0B
Q2 24
$492.0M
$-3.6B
Gross Margin
RJF
RJF
VRTX
VRTX
Q1 26
86.8%
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
RJF
RJF
VRTX
VRTX
Q1 26
38.1%
Q4 25
37.8%
Q3 25
38.6%
Q2 25
14.7%
38.8%
Q1 25
17.5%
22.7%
Q4 24
18.6%
35.2%
Q3 24
40.3%
Q2 24
17.1%
-132.9%
Net Margin
RJF
RJF
VRTX
VRTX
Q1 26
14.1%
34.5%
Q4 25
13.5%
37.3%
Q3 25
14.4%
35.2%
Q2 25
11.3%
34.8%
Q1 25
12.9%
23.3%
Q4 24
14.9%
31.4%
Q3 24
15.0%
37.7%
Q2 24
13.1%
-135.8%
EPS (diluted)
RJF
RJF
VRTX
VRTX
Q1 26
$2.83
$4.02
Q4 25
$2.79
$4.64
Q3 25
$2.96
$4.20
Q2 25
$2.12
$3.99
Q1 25
$2.36
$2.49
Q4 24
$2.86
$3.62
Q3 24
$2.85
$4.01
Q2 24
$2.31
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RJF
RJF
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$5.4B
Total DebtLower is stronger
Stockholders' EquityBook value
$52.0M
$19.4B
Total Assets
$91.9B
$26.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RJF
RJF
VRTX
VRTX
Q1 26
$5.4B
Q4 25
$9.9B
$6.6B
Q3 25
$11.4B
$6.3B
Q2 25
$9.2B
$6.4B
Q1 25
$9.7B
$6.2B
Q4 24
$10.0B
$6.1B
Q3 24
$11.0B
$6.5B
Q2 24
$9.1B
$5.8B
Stockholders' Equity
RJF
RJF
VRTX
VRTX
Q1 26
$52.0M
$19.4B
Q4 25
$12.6B
$18.7B
Q3 25
$12.5B
$17.3B
Q2 25
$12.3B
$17.2B
Q1 25
$12.2B
$16.5B
Q4 24
$11.9B
$16.4B
Q3 24
$11.7B
$15.6B
Q2 24
$11.2B
$14.8B
Total Assets
RJF
RJF
VRTX
VRTX
Q1 26
$91.9B
$26.5B
Q4 25
$88.8B
$25.6B
Q3 25
$88.2B
$24.9B
Q2 25
$84.8B
$24.0B
Q1 25
$83.1B
$22.9B
Q4 24
$82.3B
$22.5B
Q3 24
$83.0B
$22.2B
Q2 24
$80.6B
$20.1B

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

RJF
RJF

Private Client Group$2.8B73%
Bank$486.0M13%
Capital Markets$464.0M12%
Other$99.0M3%

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

Related Comparisons