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Side-by-side financial comparison of Relay Therapeutics, Inc. (RLAY) and Taysha Gene Therapies, Inc. (TSHA). Click either name above to swap in a different company.

Relay Therapeutics, Inc. is the larger business by last-quarter revenue ($7.0M vs $5.5M, roughly 1.3× Taysha Gene Therapies, Inc.).

Relay Therapeutics is a clinical-stage biotechnology company focused on developing precision oncology therapies. It leverages advanced computational modeling of protein dynamics, paired with cutting-edge experimental biology, to design targeted medicines for previously intractable cancer types, serving global oncology care markets and patient populations.

Taysha Gene Therapies, Inc. is a clinical-stage biotechnology company specializing in developing adeno-associated virus (AAV)-based gene therapies for rare monogenic central nervous system disorders with high unmet medical needs. Its core pipeline targets serious life-threatening neurological conditions, with primary operations and market focus across North America and European regions.

RLAY vs TSHA — Head-to-Head

Bigger by revenue
RLAY
RLAY
1.3× larger
RLAY
$7.0M
$5.5M
TSHA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
RLAY
RLAY
TSHA
TSHA
Revenue
$7.0M
$5.5M
Net Profit
$-27.9M
Gross Margin
Operating Margin
-516.0%
Net Margin
-507.8%
Revenue YoY
171.3%
Net Profit YoY
-48.3%
EPS (diluted)
$-0.08

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RLAY
RLAY
TSHA
TSHA
Q4 25
$7.0M
$5.5M
Q3 25
$0
$0
Q2 25
$2.0M
Q1 25
$7.7M
$2.3M
Q4 24
$0
$2.0M
Q3 24
$0
$1.8M
Q2 24
$0
$1.1M
Q1 24
$10.0M
$3.4M
Net Profit
RLAY
RLAY
TSHA
TSHA
Q4 25
$-27.9M
Q3 25
$-74.1M
$-32.7M
Q2 25
$-26.9M
Q1 25
$-77.1M
$-21.5M
Q4 24
$-18.8M
Q3 24
$-88.1M
$-25.5M
Q2 24
$-92.2M
$-20.9M
Q1 24
$-81.4M
$-24.1M
Operating Margin
RLAY
RLAY
TSHA
TSHA
Q4 25
-516.0%
Q3 25
Q2 25
-1347.1%
Q1 25
-1105.2%
-930.5%
Q4 24
-985.8%
Q3 24
-1448.4%
Q2 24
-1915.4%
Q1 24
-903.0%
-713.3%
Net Margin
RLAY
RLAY
TSHA
TSHA
Q4 25
-507.8%
Q3 25
Q2 25
-1353.6%
Q1 25
-1003.6%
-935.2%
Q4 24
-929.0%
Q3 24
-1427.5%
Q2 24
-1882.0%
Q1 24
-813.3%
-705.4%
EPS (diluted)
RLAY
RLAY
TSHA
TSHA
Q4 25
$-0.08
Q3 25
$-0.43
$-0.09
Q2 25
$-0.09
Q1 25
$-0.46
$-0.08
Q4 24
$-0.07
Q3 24
$-0.63
$-0.10
Q2 24
$-0.69
$-0.09
Q1 24
$-0.62
$-0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RLAY
RLAY
TSHA
TSHA
Cash + ST InvestmentsLiquidity on hand
$84.0M
$319.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$567.1M
$246.9M
Total Assets
$621.3M
$343.3M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RLAY
RLAY
TSHA
TSHA
Q4 25
$84.0M
$319.8M
Q3 25
$91.6M
$297.3M
Q2 25
$312.8M
Q1 25
$93.5M
$116.6M
Q4 24
$124.3M
$139.0M
Q3 24
$152.4M
$157.7M
Q2 24
$134.1M
$172.7M
Q1 24
$152.9M
$124.0M
Stockholders' Equity
RLAY
RLAY
TSHA
TSHA
Q4 25
$567.1M
$246.9M
Q3 25
$607.7M
$219.0M
Q2 25
$248.7M
Q1 25
$721.1M
$55.1M
Q4 24
$777.8M
$71.5M
Q3 24
$838.9M
$88.8M
Q2 24
$681.7M
$108.9M
Q1 24
$745.8M
$53.8M
Total Assets
RLAY
RLAY
TSHA
TSHA
Q4 25
$621.3M
$343.3M
Q3 25
$670.0M
$316.6M
Q2 25
$333.3M
Q1 25
$799.4M
$138.4M
Q4 24
$871.3M
$160.4M
Q3 24
$930.1M
$180.2M
Q2 24
$772.5M
$200.4M
Q1 24
$841.4M
$153.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
RLAY
RLAY
TSHA
TSHA
Operating Cash FlowLast quarter
$-235.5M
$-26.7M
Free Cash FlowOCF − Capex
$-235.9M
FCF MarginFCF / Revenue
-3370.0%
Capex IntensityCapex / Revenue
5.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-622.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
RLAY
RLAY
TSHA
TSHA
Q4 25
$-235.5M
$-26.7M
Q3 25
$-62.1M
$-24.2M
Q2 25
$-20.2M
Q1 25
$-73.2M
$-22.0M
Q4 24
$-249.1M
$-18.3M
Q3 24
$-75.1M
$-21.6M
Q2 24
$-65.8M
$-21.5M
Q1 24
$-50.3M
$-19.8M
Free Cash Flow
RLAY
RLAY
TSHA
TSHA
Q4 25
$-235.9M
Q3 25
$-62.1M
$-24.3M
Q2 25
Q1 25
$-73.6M
Q4 24
$-251.1M
$-18.3M
Q3 24
$-75.3M
$-21.6M
Q2 24
$-65.8M
$-21.7M
Q1 24
$-52.1M
$-19.9M
FCF Margin
RLAY
RLAY
TSHA
TSHA
Q4 25
-3370.0%
Q3 25
Q2 25
Q1 25
-958.4%
Q4 24
-905.5%
Q3 24
-1210.9%
Q2 24
-1951.9%
Q1 24
-520.7%
-584.5%
Capex Intensity
RLAY
RLAY
TSHA
TSHA
Q4 25
5.9%
Q3 25
Q2 25
Q1 25
5.0%
Q4 24
0.1%
Q3 24
2.0%
Q2 24
18.1%
Q1 24
17.8%
4.1%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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