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Side-by-side financial comparison of RHYTHM PHARMACEUTICALS, INC. (RYTM) and Sezzle Inc. (SEZL). Click either name above to swap in a different company.

Sezzle Inc. is the larger business by last-quarter revenue ($78.2M vs $57.3M, roughly 1.4× RHYTHM PHARMACEUTICALS, INC.). Sezzle Inc. runs the higher net margin — 54.6% vs -83.0%, a 137.6% gap on every dollar of revenue. On growth, Sezzle Inc. posted the faster year-over-year revenue change (61.6% vs 36.9%). Over the past eight quarters, Sezzle Inc.'s revenue compounded faster (76.0% CAGR vs 48.5%).

Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.

Sezzle is a publicly traded financial technology company headquartered in Minneapolis, U.S, with operations in the United States and Canada. The company provides an alternative payment platform offering interest-free installment plans at selected online stores. As of June 2021, the Sezzle platform had over 10 million user sign-ups and over 48,000 participating merchants.

RYTM vs SEZL — Head-to-Head

Bigger by revenue
SEZL
SEZL
1.4× larger
SEZL
$78.2M
$57.3M
RYTM
Growing faster (revenue YoY)
SEZL
SEZL
+24.7% gap
SEZL
61.6%
36.9%
RYTM
Higher net margin
SEZL
SEZL
137.6% more per $
SEZL
54.6%
-83.0%
RYTM
Faster 2-yr revenue CAGR
SEZL
SEZL
Annualised
SEZL
76.0%
48.5%
RYTM

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
RYTM
RYTM
SEZL
SEZL
Revenue
$57.3M
$78.2M
Net Profit
$-47.5M
$42.7M
Gross Margin
91.6%
Operating Margin
-82.2%
70.6%
Net Margin
-83.0%
54.6%
Revenue YoY
36.9%
61.6%
Net Profit YoY
-9.6%
68.3%
EPS (diluted)
$-0.73
$1.19

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RYTM
RYTM
SEZL
SEZL
Q4 25
$57.3M
$78.2M
Q3 25
$51.3M
$57.5M
Q2 25
$48.5M
$52.0M
Q1 25
$32.7M
$48.2M
Q4 24
$41.8M
$48.4M
Q3 24
$33.3M
$35.6M
Q2 24
$29.1M
$30.2M
Q1 24
$26.0M
$25.2M
Net Profit
RYTM
RYTM
SEZL
SEZL
Q4 25
$-47.5M
$42.7M
Q3 25
$-52.9M
$26.7M
Q2 25
$-46.6M
$27.6M
Q1 25
$-49.5M
$36.2M
Q4 24
$-43.3M
$25.4M
Q3 24
$-43.6M
$15.4M
Q2 24
$-32.3M
$29.7M
Q1 24
$-141.4M
$8.0M
Gross Margin
RYTM
RYTM
SEZL
SEZL
Q4 25
91.6%
Q3 25
89.3%
Q2 25
88.6%
Q1 25
88.8%
Q4 24
90.9%
Q3 24
88.5%
Q2 24
89.9%
Q1 24
89.2%
Operating Margin
RYTM
RYTM
SEZL
SEZL
Q4 25
-82.2%
70.6%
Q3 25
-102.6%
61.9%
Q2 25
-93.4%
69.4%
Q1 25
-143.7%
Q4 24
-98.6%
63.8%
Q3 24
-132.0%
58.6%
Q2 24
-139.2%
55.3%
Q1 24
-538.7%
54.8%
Net Margin
RYTM
RYTM
SEZL
SEZL
Q4 25
-83.0%
54.6%
Q3 25
-103.1%
46.4%
Q2 25
-96.1%
53.1%
Q1 25
-151.4%
75.1%
Q4 24
-103.6%
52.4%
Q3 24
-131.2%
43.4%
Q2 24
-110.9%
98.4%
Q1 24
-544.4%
31.7%
EPS (diluted)
RYTM
RYTM
SEZL
SEZL
Q4 25
$-0.73
$1.19
Q3 25
$-0.82
$0.75
Q2 25
$-0.75
$0.78
Q1 25
$-0.81
$1.00
Q4 24
$-0.71
$0.71
Q3 24
$-0.73
$0.44
Q2 24
$-0.55
$0.82
Q1 24
$-2.35
$0.22

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RYTM
RYTM
SEZL
SEZL
Cash + ST InvestmentsLiquidity on hand
$388.9M
$64.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$139.1M
$169.8M
Total Assets
$480.2M
$400.2M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RYTM
RYTM
SEZL
SEZL
Q4 25
$388.9M
$64.1M
Q3 25
$416.1M
$104.1M
Q2 25
$291.0M
$88.9M
Q1 25
$314.5M
$88.9M
Q4 24
$320.6M
$73.2M
Q3 24
$298.4M
$80.1M
Q2 24
$319.1M
$58.0M
Q1 24
$201.2M
$77.8M
Stockholders' Equity
RYTM
RYTM
SEZL
SEZL
Q4 25
$139.1M
$169.8M
Q3 25
$148.8M
$155.3M
Q2 25
$-11.9M
$130.4M
Q1 25
$18.9M
$125.8M
Q4 24
$21.7M
$87.8M
Q3 24
$11.2M
$61.1M
Q2 24
$39.3M
$50.3M
Q1 24
$61.6M
$29.6M
Total Assets
RYTM
RYTM
SEZL
SEZL
Q4 25
$480.2M
$400.2M
Q3 25
$506.9M
$367.0M
Q2 25
$372.7M
$350.6M
Q1 25
$386.7M
$298.1M
Q4 24
$392.3M
$298.4M
Q3 24
$363.6M
$252.9M
Q2 24
$381.8M
$212.1M
Q1 24
$258.7M
$195.7M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
RYTM
RYTM
SEZL
SEZL
Operating Cash FlowLast quarter
$-25.4M
$70.6M
Free Cash FlowOCF − Capex
$70.6M
FCF MarginFCF / Revenue
90.2%
Capex IntensityCapex / Revenue
0.1%
Cash ConversionOCF / Net Profit
1.65×
TTM Free Cash FlowTrailing 4 quarters
$209.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
RYTM
RYTM
SEZL
SEZL
Q4 25
$-25.4M
$70.6M
Q3 25
$-26.6M
$63.7M
Q2 25
$-23.3M
$23.1M
Q1 25
$-40.4M
$52.5M
Q4 24
$-18.8M
$57.4M
Q3 24
$-25.2M
$35.1M
Q2 24
$-29.1M
$22.2M
Q1 24
$-40.7M
$16.0M
Free Cash Flow
RYTM
RYTM
SEZL
SEZL
Q4 25
$70.6M
Q3 25
$63.6M
Q2 25
$22.7M
Q1 25
$52.5M
Q4 24
$57.4M
Q3 24
$35.1M
Q2 24
$22.2M
Q1 24
$16.0M
FCF Margin
RYTM
RYTM
SEZL
SEZL
Q4 25
90.2%
Q3 25
110.6%
Q2 25
43.6%
Q1 25
108.9%
Q4 24
118.5%
Q3 24
98.6%
Q2 24
73.4%
Q1 24
63.3%
Capex Intensity
RYTM
RYTM
SEZL
SEZL
Q4 25
0.1%
Q3 25
0.3%
Q2 25
0.8%
Q1 25
0.1%
Q4 24
0.1%
Q3 24
0.0%
Q2 24
0.1%
Q1 24
0.0%
Cash Conversion
RYTM
RYTM
SEZL
SEZL
Q4 25
1.65×
Q3 25
2.39×
Q2 25
0.84×
Q1 25
1.45×
Q4 24
2.26×
Q3 24
2.27×
Q2 24
0.75×
Q1 24
2.00×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

RYTM
RYTM

Segment breakdown not available.

SEZL
SEZL

Merchant And Partner Income$28.9M37%
Transaction Income$25.9M33%
Income From Other Services Late Payment Fees$20.5M26%
Other$2.9M4%

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