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Side-by-side financial comparison of RHYTHM PHARMACEUTICALS, INC. (RYTM) and Smart Sand, Inc. (SND). Click either name above to swap in a different company.
Smart Sand, Inc. is the larger business by last-quarter revenue ($86.0M vs $57.3M, roughly 1.5× RHYTHM PHARMACEUTICALS, INC.). Smart Sand, Inc. runs the higher net margin — 1.4% vs -83.0%, a 84.3% gap on every dollar of revenue. On growth, RHYTHM PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (36.9% vs -5.8%). Over the past eight quarters, RHYTHM PHARMACEUTICALS, INC.'s revenue compounded faster (48.5% CAGR vs 1.8%).
Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.
Sand 9 is a fabless Micro-electromechanical system (MEMS) company based in Cambridge, Massachusetts. Sand 9 developed a piezoelectric MEMS resonator to serve as an alternative for quartz timing devices in applications such as smart phones, low-power wireless devices, and communications infrastructure equipment.
RYTM vs SND — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $57.3M | $86.0M |
| Net Profit | $-47.5M | $1.2M |
| Gross Margin | 91.6% | 13.0% |
| Operating Margin | -82.2% | -3.1% |
| Net Margin | -83.0% | 1.4% |
| Revenue YoY | 36.9% | -5.8% |
| Net Profit YoY | -9.6% | -68.5% |
| EPS (diluted) | $-0.73 | $0.03 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $57.3M | $86.0M | ||
| Q3 25 | $51.3M | $92.8M | ||
| Q2 25 | $48.5M | $85.8M | ||
| Q1 25 | $32.7M | $65.6M | ||
| Q4 24 | $41.8M | $91.4M | ||
| Q3 24 | $33.3M | $63.2M | ||
| Q2 24 | $29.1M | $73.8M | ||
| Q1 24 | $26.0M | $83.1M |
| Q4 25 | $-47.5M | $1.2M | ||
| Q3 25 | $-52.9M | $3.0M | ||
| Q2 25 | $-46.6M | $21.4M | ||
| Q1 25 | $-49.5M | $-24.2M | ||
| Q4 24 | $-43.3M | $3.7M | ||
| Q3 24 | $-43.6M | $-98.0K | ||
| Q2 24 | $-32.3M | $-430.0K | ||
| Q1 24 | $-141.4M | $-216.0K |
| Q4 25 | 91.6% | 13.0% | ||
| Q3 25 | 89.3% | 16.1% | ||
| Q2 25 | 88.6% | 10.4% | ||
| Q1 25 | 88.8% | 4.2% | ||
| Q4 24 | 90.9% | 14.7% | ||
| Q3 24 | 88.5% | 10.3% | ||
| Q2 24 | 89.9% | 17.7% | ||
| Q1 24 | 89.2% | 14.2% |
| Q4 25 | -82.2% | -3.1% | ||
| Q3 25 | -102.6% | 5.8% | ||
| Q2 25 | -93.4% | -0.1% | ||
| Q1 25 | -143.7% | -10.8% | ||
| Q4 24 | -98.6% | 3.9% | ||
| Q3 24 | -132.0% | -7.8% | ||
| Q2 24 | -139.2% | 4.8% | ||
| Q1 24 | -538.7% | 0.9% |
| Q4 25 | -83.0% | 1.4% | ||
| Q3 25 | -103.1% | 3.2% | ||
| Q2 25 | -96.1% | 24.9% | ||
| Q1 25 | -151.4% | -37.0% | ||
| Q4 24 | -103.6% | 4.1% | ||
| Q3 24 | -131.2% | -0.2% | ||
| Q2 24 | -110.9% | -0.6% | ||
| Q1 24 | -544.4% | -0.3% |
| Q4 25 | $-0.73 | $0.03 | ||
| Q3 25 | $-0.82 | $0.08 | ||
| Q2 25 | $-0.75 | $0.54 | ||
| Q1 25 | $-0.81 | $-0.62 | ||
| Q4 24 | $-0.71 | $0.10 | ||
| Q3 24 | $-0.73 | $0.00 | ||
| Q2 24 | $-0.55 | $-0.01 | ||
| Q1 24 | $-2.35 | $-0.01 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $388.9M | $22.6M |
| Total DebtLower is stronger | — | $15.0M |
| Stockholders' EquityBook value | $139.1M | $239.7M |
| Total Assets | $480.2M | $340.0M |
| Debt / EquityLower = less leverage | — | 0.06× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $388.9M | $22.6M | ||
| Q3 25 | $416.1M | $5.1M | ||
| Q2 25 | $291.0M | $4.3M | ||
| Q1 25 | $314.5M | $5.1M | ||
| Q4 24 | $320.6M | $1.6M | ||
| Q3 24 | $298.4M | $7.2M | ||
| Q2 24 | $319.1M | $6.3M | ||
| Q1 24 | $201.2M | $4.6M |
| Q4 25 | — | $15.0M | ||
| Q3 25 | — | $14.3M | ||
| Q2 25 | — | $23.5M | ||
| Q1 25 | — | $13.7M | ||
| Q4 24 | — | $14.7M | ||
| Q3 24 | — | $15.7M | ||
| Q2 24 | — | $17.1M | ||
| Q1 24 | — | $25.5M |
| Q4 25 | $139.1M | $239.7M | ||
| Q3 25 | $148.8M | $239.9M | ||
| Q2 25 | $-11.9M | $240.5M | ||
| Q1 25 | $18.9M | $219.9M | ||
| Q4 24 | $21.7M | $243.8M | ||
| Q3 24 | $11.2M | $243.6M | ||
| Q2 24 | $39.3M | $242.9M | ||
| Q1 24 | $61.6M | $242.5M |
| Q4 25 | $480.2M | $340.0M | ||
| Q3 25 | $506.9M | $343.1M | ||
| Q2 25 | $372.7M | $345.8M | ||
| Q1 25 | $386.7M | $326.9M | ||
| Q4 24 | $392.3M | $341.5M | ||
| Q3 24 | $363.6M | $335.8M | ||
| Q2 24 | $381.8M | $341.8M | ||
| Q1 24 | $258.7M | $349.3M |
| Q4 25 | — | 0.06× | ||
| Q3 25 | — | 0.06× | ||
| Q2 25 | — | 0.10× | ||
| Q1 25 | — | 0.06× | ||
| Q4 24 | — | 0.06× | ||
| Q3 24 | — | 0.06× | ||
| Q2 24 | — | 0.07× | ||
| Q1 24 | — | 0.11× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-25.4M | $22.4M |
| Free Cash FlowOCF − Capex | — | $20.4M |
| FCF MarginFCF / Revenue | — | 23.7% |
| Capex IntensityCapex / Revenue | — | 2.3% |
| Cash ConversionOCF / Net Profit | — | 18.99× |
| TTM Free Cash FlowTrailing 4 quarters | — | $32.5M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-25.4M | $22.4M | ||
| Q3 25 | $-26.6M | $18.2M | ||
| Q2 25 | $-23.3M | $-5.1M | ||
| Q1 25 | $-40.4M | $8.7M | ||
| Q4 24 | $-18.8M | $1.0M | ||
| Q3 24 | $-25.2M | $5.8M | ||
| Q2 24 | $-29.1M | $14.9M | ||
| Q1 24 | $-40.7M | $-3.9M |
| Q4 25 | — | $20.4M | ||
| Q3 25 | — | $14.8M | ||
| Q2 25 | — | $-7.8M | ||
| Q1 25 | — | $5.2M | ||
| Q4 24 | — | $-840.0K | ||
| Q3 24 | — | $3.7M | ||
| Q2 24 | — | $13.5M | ||
| Q1 24 | — | $-5.5M |
| Q4 25 | — | 23.7% | ||
| Q3 25 | — | 15.9% | ||
| Q2 25 | — | -9.1% | ||
| Q1 25 | — | 7.9% | ||
| Q4 24 | — | -0.9% | ||
| Q3 24 | — | 5.8% | ||
| Q2 24 | — | 18.3% | ||
| Q1 24 | — | -6.6% |
| Q4 25 | — | 2.3% | ||
| Q3 25 | — | 3.6% | ||
| Q2 25 | — | 3.1% | ||
| Q1 25 | — | 5.4% | ||
| Q4 24 | — | 2.1% | ||
| Q3 24 | — | 3.4% | ||
| Q2 24 | — | 1.8% | ||
| Q1 24 | — | 2.0% |
| Q4 25 | — | 18.99× | ||
| Q3 25 | — | 6.05× | ||
| Q2 25 | — | -0.24× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 0.28× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
RYTM
Segment breakdown not available.
SND
| Sand | $85.1M | 99% |
| Smart Systems Segment | $980.0K | 1% |
