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Side-by-side financial comparison of RHYTHM PHARMACEUTICALS, INC. (RYTM) and VINCE HOLDING CORP. (VNCE). Click either name above to swap in a different company.
VINCE HOLDING CORP. is the larger business by last-quarter revenue ($85.1M vs $57.3M, roughly 1.5× RHYTHM PHARMACEUTICALS, INC.). VINCE HOLDING CORP. runs the higher net margin — 3.2% vs -83.0%, a 86.2% gap on every dollar of revenue. On growth, RHYTHM PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (36.9% vs 6.2%). Over the past eight quarters, RHYTHM PHARMACEUTICALS, INC.'s revenue compounded faster (48.5% CAGR vs 6.3%).
Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.
VINCE. is a contemporary clothing fashion brand founded in 2002. In 2023 Authentic Brands Group purchased its intellectual property in a $76.5 million deal.
RYTM vs VNCE — Head-to-Head
Income Statement — Q4 FY2025 vs Q3 FY2026
| Metric | | |
|---|---|---|
| Revenue | $57.3M | $85.1M |
| Net Profit | $-47.5M | $2.7M |
| Gross Margin | 91.6% | 49.2% |
| Operating Margin | -82.2% | 6.4% |
| Net Margin | -83.0% | 3.2% |
| Revenue YoY | 36.9% | 6.2% |
| Net Profit YoY | -9.6% | -37.3% |
| EPS (diluted) | $-0.73 | $0.21 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $57.3M | $85.1M | ||
| Q3 25 | $51.3M | $73.2M | ||
| Q2 25 | $48.5M | $57.9M | ||
| Q1 25 | $32.7M | $80.0M | ||
| Q4 24 | $41.8M | $80.2M | ||
| Q3 24 | $33.3M | $74.2M | ||
| Q2 24 | $29.1M | $59.2M | ||
| Q1 24 | $26.0M | $75.3M |
| Q4 25 | $-47.5M | $2.7M | ||
| Q3 25 | $-52.9M | $12.1M | ||
| Q2 25 | $-46.6M | $-4.8M | ||
| Q1 25 | $-49.5M | $-28.3M | ||
| Q4 24 | $-43.3M | $4.3M | ||
| Q3 24 | $-43.6M | $569.0K | ||
| Q2 24 | $-32.3M | $4.4M | ||
| Q1 24 | $-141.4M | $-4.7M |
| Q4 25 | 91.6% | 49.2% | ||
| Q3 25 | 89.3% | 50.4% | ||
| Q2 25 | 88.6% | 50.3% | ||
| Q1 25 | 88.8% | 50.1% | ||
| Q4 24 | 90.9% | 50.0% | ||
| Q3 24 | 88.5% | 47.4% | ||
| Q2 24 | 89.9% | 50.6% | ||
| Q1 24 | 89.2% | 45.4% |
| Q4 25 | -82.2% | 6.4% | ||
| Q3 25 | -102.6% | 15.2% | ||
| Q2 25 | -93.4% | -7.7% | ||
| Q1 25 | -143.7% | -37.1% | ||
| Q4 24 | -98.6% | 7.2% | ||
| Q3 24 | -132.0% | 1.5% | ||
| Q2 24 | -139.2% | 9.5% | ||
| Q1 24 | -538.7% | -2.2% |
| Q4 25 | -83.0% | 3.2% | ||
| Q3 25 | -103.1% | 16.5% | ||
| Q2 25 | -96.1% | -8.3% | ||
| Q1 25 | -151.4% | -35.5% | ||
| Q4 24 | -103.6% | 5.4% | ||
| Q3 24 | -131.2% | 0.8% | ||
| Q2 24 | -110.9% | 7.4% | ||
| Q1 24 | -544.4% | -6.2% |
| Q4 25 | $-0.73 | $0.21 | ||
| Q3 25 | $-0.82 | $0.93 | ||
| Q2 25 | $-0.75 | $-0.37 | ||
| Q1 25 | $-0.81 | $-2.25 | ||
| Q4 24 | $-0.71 | $0.34 | ||
| Q3 24 | $-0.73 | $0.05 | ||
| Q2 24 | $-0.55 | $0.35 | ||
| Q1 24 | $-2.35 | $-0.37 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $388.9M | $1.1M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $139.1M | $53.4M |
| Total Assets | $480.2M | $246.0M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $388.9M | $1.1M | ||
| Q3 25 | $416.1M | $777.0K | ||
| Q2 25 | $291.0M | $2.6M | ||
| Q1 25 | $314.5M | $607.0K | ||
| Q4 24 | $320.6M | $892.0K | ||
| Q3 24 | $298.4M | $711.0K | ||
| Q2 24 | $319.1M | $739.0K | ||
| Q1 24 | $201.2M | $357.0K |
| Q4 25 | $139.1M | $53.4M | ||
| Q3 25 | $148.8M | $49.3M | ||
| Q2 25 | $-11.9M | $37.2M | ||
| Q1 25 | $18.9M | $41.8M | ||
| Q4 24 | $21.7M | $57.1M | ||
| Q3 24 | $11.2M | $52.4M | ||
| Q2 24 | $39.3M | $51.7M | ||
| Q1 24 | $61.6M | $47.2M |
| Q4 25 | $480.2M | $246.0M | ||
| Q3 25 | $506.9M | $239.0M | ||
| Q2 25 | $372.7M | $218.0M | ||
| Q1 25 | $386.7M | $222.7M | ||
| Q4 24 | $392.3M | $254.7M | ||
| Q3 24 | $363.6M | $253.6M | ||
| Q2 24 | $381.8M | $223.1M | ||
| Q1 24 | $258.7M | $225.1M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-25.4M | $-5.1M |
| Free Cash FlowOCF − Capex | — | $-5.7M |
| FCF MarginFCF / Revenue | — | -6.7% |
| Capex IntensityCapex / Revenue | — | 0.7% |
| Cash ConversionOCF / Net Profit | — | -1.86× |
| TTM Free Cash FlowTrailing 4 quarters | — | $4.3M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-25.4M | $-5.1M | ||
| Q3 25 | $-26.6M | $4.2M | ||
| Q2 25 | $-23.3M | $-11.8M | ||
| Q1 25 | $-40.4M | $22.7M | ||
| Q4 24 | $-18.8M | $6.4M | ||
| Q3 24 | $-25.2M | $-3.2M | ||
| Q2 24 | $-29.1M | $-3.9M | ||
| Q1 24 | $-40.7M | $14.8M |
| Q4 25 | — | $-5.7M | ||
| Q3 25 | — | $2.1M | ||
| Q2 25 | — | $-13.2M | ||
| Q1 25 | — | $21.2M | ||
| Q4 24 | — | $5.1M | ||
| Q3 24 | — | $-3.9M | ||
| Q2 24 | — | $-4.6M | ||
| Q1 24 | — | $14.2M |
| Q4 25 | — | -6.7% | ||
| Q3 25 | — | 2.9% | ||
| Q2 25 | — | -22.9% | ||
| Q1 25 | — | 26.5% | ||
| Q4 24 | — | 6.4% | ||
| Q3 24 | — | -5.2% | ||
| Q2 24 | — | -7.8% | ||
| Q1 24 | — | 18.9% |
| Q4 25 | — | 0.7% | ||
| Q3 25 | — | 2.9% | ||
| Q2 25 | — | 2.5% | ||
| Q1 25 | — | 1.9% | ||
| Q4 24 | — | 1.6% | ||
| Q3 24 | — | 0.9% | ||
| Q2 24 | — | 1.3% | ||
| Q1 24 | — | 0.7% |
| Q4 25 | — | -1.86× | ||
| Q3 25 | — | 0.35× | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 1.48× | ||
| Q3 24 | — | -5.61× | ||
| Q2 24 | — | -0.89× | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
RYTM
Segment breakdown not available.
VNCE
| Vince Wholesale | $52.0M | 61% |
| Vince Direct To Consumer | $33.1M | 39% |
