vs
Side-by-side financial comparison of SHOULDER INNOVATIONS, INC. (SI) and TriSalus Life Sciences, Inc. (TLSI). Click either name above to swap in a different company.
TriSalus Life Sciences, Inc. is the larger business by last-quarter revenue ($13.2M vs $11.8M, roughly 1.1× SHOULDER INNOVATIONS, INC.). TriSalus Life Sciences, Inc. runs the higher net margin — -73.9% vs -74.3%, a 0.4% gap on every dollar of revenue. TriSalus Life Sciences, Inc. produced more free cash flow last quarter ($-2.5M vs $-11.4M).
Shoulder Innovations, Inc. is a medical technology firm specializing in design, development, and commercialization of innovative orthopedic devices for shoulder replacement surgery. Its products reduce surgical complications, improve patient outcomes, and are sold to orthopedic surgeons and healthcare providers across North America and Western Europe.
TriSalus Life Sciences, Inc. is a clinical-stage biotechnology company focused on advancing immuno-oncology and interventional oncology solutions. It develops proprietary targeted drug delivery technologies designed to improve treatment efficacy for patients with liver, pancreatic and other hard-to-treat solid tumors, primarily operating in North American markets via partnerships with clinical care and research institutions.
SI vs TLSI — Head-to-Head
Income Statement — Q3 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $11.8M | $13.2M |
| Net Profit | $-8.7M | $-9.8M |
| Gross Margin | 76.2% | 86.7% |
| Operating Margin | -65.0% | -24.8% |
| Net Margin | -74.3% | -73.9% |
| Revenue YoY | — | 59.8% |
| Net Profit YoY | — | 3.5% |
| EPS (diluted) | $-0.64 | $-0.22 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | — | $13.2M | ||
| Q3 25 | $11.8M | $11.6M | ||
| Q2 25 | $11.0M | $11.2M | ||
| Q1 25 | — | $9.2M | ||
| Q4 24 | — | $8.3M | ||
| Q3 24 | — | $7.3M | ||
| Q2 24 | — | $7.4M | ||
| Q1 24 | — | $6.5M |
| Q4 25 | — | $-9.8M | ||
| Q3 25 | $-8.7M | $-10.8M | ||
| Q2 25 | $-19.2M | $-8.3M | ||
| Q1 25 | — | $-10.4M | ||
| Q4 24 | — | $-10.1M | ||
| Q3 24 | — | $-2.4M | ||
| Q2 24 | — | $-4.3M | ||
| Q1 24 | — | $-13.2M |
| Q4 25 | — | 86.7% | ||
| Q3 25 | 76.2% | 83.5% | ||
| Q2 25 | 76.2% | 83.9% | ||
| Q1 25 | — | 83.7% | ||
| Q4 24 | — | 85.3% | ||
| Q3 24 | — | 86.3% | ||
| Q2 24 | — | 87.6% | ||
| Q1 24 | — | 85.0% |
| Q4 25 | — | -24.8% | ||
| Q3 25 | -65.0% | -77.9% | ||
| Q2 25 | -53.2% | -65.4% | ||
| Q1 25 | — | -79.9% | ||
| Q4 24 | — | -91.8% | ||
| Q3 24 | — | -118.9% | ||
| Q2 24 | — | -111.0% | ||
| Q1 24 | — | -180.8% |
| Q4 25 | — | -73.9% | ||
| Q3 25 | -74.3% | -93.5% | ||
| Q2 25 | -174.3% | -73.9% | ||
| Q1 25 | — | -113.2% | ||
| Q4 24 | — | -122.4% | ||
| Q3 24 | — | -32.6% | ||
| Q2 24 | — | -58.8% | ||
| Q1 24 | — | -204.5% |
| Q4 25 | — | $-0.22 | ||
| Q3 25 | $-0.64 | $-0.96 | ||
| Q2 25 | $-165.53 | $-0.27 | ||
| Q1 25 | — | $-0.39 | ||
| Q4 24 | — | $-0.38 | ||
| Q3 24 | — | $-0.12 | ||
| Q2 24 | — | $-0.21 | ||
| Q1 24 | — | $-0.60 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $54.9M | $20.4M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $147.8M | $-33.9M |
| Total Assets | $177.8M | $35.3M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $20.4M | ||
| Q3 25 | $54.9M | $22.7M | ||
| Q2 25 | $27.1M | $26.5M | ||
| Q1 25 | — | $13.0M | ||
| Q4 24 | — | $8.5M | ||
| Q3 24 | — | $11.3M | ||
| Q2 24 | — | $16.5M | ||
| Q1 24 | — | $4.0M |
| Q4 25 | — | $-33.9M | ||
| Q3 25 | $147.8M | $-26.7M | ||
| Q2 25 | $-78.2M | $-19.4M | ||
| Q1 25 | — | $-34.4M | ||
| Q4 24 | — | $-25.9M | ||
| Q3 24 | — | $-20.4M | ||
| Q2 24 | — | $-25.3M | ||
| Q1 24 | — | $-36.0M |
| Q4 25 | — | $35.3M | ||
| Q3 25 | $177.8M | $36.5M | ||
| Q2 25 | $77.8M | $41.3M | ||
| Q1 25 | — | $28.6M | ||
| Q4 24 | — | $24.0M | ||
| Q3 24 | — | $27.5M | ||
| Q2 24 | — | $32.4M | ||
| Q1 24 | — | $17.9M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-8.6M | $-2.5M |
| Free Cash FlowOCF − Capex | $-11.4M | $-2.5M |
| FCF MarginFCF / Revenue | -96.7% | -19.1% |
| Capex IntensityCapex / Revenue | 23.9% | 0.3% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $-19.1M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $-2.5M | ||
| Q3 25 | $-8.6M | $-3.7M | ||
| Q2 25 | $-11.3M | $-7.3M | ||
| Q1 25 | — | $-4.5M | ||
| Q4 24 | — | $-5.7M | ||
| Q3 24 | — | $-10.8M | ||
| Q2 24 | — | $-13.4M | ||
| Q1 24 | — | $-10.9M |
| Q4 25 | — | $-2.5M | ||
| Q3 25 | $-11.4M | $-3.9M | ||
| Q2 25 | $-13.6M | $-7.4M | ||
| Q1 25 | — | $-5.3M | ||
| Q4 24 | — | $-5.8M | ||
| Q3 24 | — | $-11.0M | ||
| Q2 24 | — | $-13.5M | ||
| Q1 24 | — | $-10.9M |
| Q4 25 | — | -19.1% | ||
| Q3 25 | -96.7% | -33.9% | ||
| Q2 25 | -123.4% | -66.1% | ||
| Q1 25 | — | -57.3% | ||
| Q4 24 | — | -69.7% | ||
| Q3 24 | — | -149.9% | ||
| Q2 24 | — | -183.1% | ||
| Q1 24 | — | -169.3% |
| Q4 25 | — | 0.3% | ||
| Q3 25 | 23.9% | 1.9% | ||
| Q2 25 | 21.0% | 0.8% | ||
| Q1 25 | — | 8.2% | ||
| Q4 24 | — | 0.6% | ||
| Q3 24 | — | 2.3% | ||
| Q2 24 | — | 0.8% | ||
| Q1 24 | — | 1.0% |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
