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Side-by-side financial comparison of Southland Holdings, Inc. (SLND) and Twist Bioscience Corp (TWST). Click either name above to swap in a different company.

Southland Holdings, Inc. is the larger business by last-quarter revenue ($104.0M vs $103.7M, roughly 1.0× Twist Bioscience Corp). Twist Bioscience Corp runs the higher net margin — -29.4% vs -208.2%, a 178.8% gap on every dollar of revenue. On growth, Twist Bioscience Corp posted the faster year-over-year revenue change (16.9% vs -61.1%). Southland Holdings, Inc. produced more free cash flow last quarter ($9.3M vs $-34.8M).

Southland Holdings, Inc. is a leading North American infrastructure construction firm. It offers full-suite services for transportation projects including highways, bridges and airports, water and wastewater system construction, and commercial site development, serving both public sector and private industry clients across regional core markets.

Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.

SLND vs TWST — Head-to-Head

Bigger by revenue
SLND
SLND
1.0× larger
SLND
$104.0M
$103.7M
TWST
Growing faster (revenue YoY)
TWST
TWST
+78.0% gap
TWST
16.9%
-61.1%
SLND
Higher net margin
TWST
TWST
178.8% more per $
TWST
-29.4%
-208.2%
SLND
More free cash flow
SLND
SLND
$44.1M more FCF
SLND
$9.3M
$-34.8M
TWST

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
SLND
SLND
TWST
TWST
Revenue
$104.0M
$103.7M
Net Profit
$-216.4M
$-30.5M
Gross Margin
-186.0%
52.0%
Operating Margin
-202.4%
-31.7%
Net Margin
-208.2%
-29.4%
Revenue YoY
-61.1%
16.9%
Net Profit YoY
-5108.5%
3.4%
EPS (diluted)
$-4.01
$-0.50

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
SLND
SLND
TWST
TWST
Q4 25
$104.0M
$103.7M
Q3 25
$213.3M
Q2 25
$215.4M
Q1 25
$239.5M
Q4 24
$267.3M
Q3 24
$173.3M
Q2 24
$251.5M
Q1 24
$288.1M
Net Profit
SLND
SLND
TWST
TWST
Q4 25
$-216.4M
$-30.5M
Q3 25
$-75.3M
Q2 25
$-10.3M
Q1 25
$-4.6M
Q4 24
$-4.2M
Q3 24
$-54.7M
Q2 24
$-46.1M
Q1 24
$-406.0K
Gross Margin
SLND
SLND
TWST
TWST
Q4 25
-186.0%
52.0%
Q3 25
1.5%
Q2 25
6.2%
Q1 25
9.0%
Q4 24
2.9%
Q3 24
-29.5%
Q2 24
-15.9%
Q1 24
7.1%
Operating Margin
SLND
SLND
TWST
TWST
Q4 25
-202.4%
-31.7%
Q3 25
-5.3%
Q2 25
-0.1%
Q1 25
2.1%
Q4 24
-3.0%
Q3 24
-39.6%
Q2 24
-22.1%
Q1 24
2.1%
Net Margin
SLND
SLND
TWST
TWST
Q4 25
-208.2%
-29.4%
Q3 25
-35.3%
Q2 25
-4.8%
Q1 25
-1.9%
Q4 24
-1.6%
Q3 24
-31.6%
Q2 24
-18.3%
Q1 24
-0.1%
EPS (diluted)
SLND
SLND
TWST
TWST
Q4 25
$-4.01
$-0.50
Q3 25
$-1.39
Q2 25
$-0.19
Q1 25
$-0.08
Q4 24
$-0.08
Q3 24
$-1.14
Q2 24
$-0.96
Q1 24
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
SLND
SLND
TWST
TWST
Cash + ST InvestmentsLiquidity on hand
$52.7M
$197.9M
Total DebtLower is stronger
$257.7M
Stockholders' EquityBook value
$-140.9M
$456.1M
Total Assets
$989.3M
$638.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
SLND
SLND
TWST
TWST
Q4 25
$52.7M
$197.9M
Q3 25
$40.5M
Q2 25
$46.5M
Q1 25
$65.1M
Q4 24
$72.2M
Q3 24
$91.4M
Q2 24
$52.4M
Q1 24
$31.2M
Total Debt
SLND
SLND
TWST
TWST
Q4 25
$257.7M
Q3 25
$267.8M
Q2 25
$278.6M
Q1 25
$288.1M
Q4 24
$300.1M
Q3 24
$318.3M
Q2 24
$307.8M
Q1 24
$302.0M
Stockholders' Equity
SLND
SLND
TWST
TWST
Q4 25
$-140.9M
$456.1M
Q3 25
$75.0M
Q2 25
$151.1M
Q1 25
$159.1M
Q4 24
$163.7M
Q3 24
$149.1M
Q2 24
$203.3M
Q1 24
$249.3M
Total Assets
SLND
SLND
TWST
TWST
Q4 25
$989.3M
$638.1M
Q3 25
$1.1B
Q2 25
$1.2B
Q1 25
$1.2B
Q4 24
$1.2B
Q3 24
$1.2B
Q2 24
$1.3B
Q1 24
$1.2B
Debt / Equity
SLND
SLND
TWST
TWST
Q4 25
Q3 25
3.57×
Q2 25
1.84×
Q1 25
1.81×
Q4 24
1.83×
Q3 24
2.14×
Q2 24
1.51×
Q1 24
1.21×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
SLND
SLND
TWST
TWST
Operating Cash FlowLast quarter
$9.7M
$-24.8M
Free Cash FlowOCF − Capex
$9.3M
$-34.8M
FCF MarginFCF / Revenue
8.9%
-33.5%
Capex IntensityCapex / Revenue
0.4%
9.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$12.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
SLND
SLND
TWST
TWST
Q4 25
$9.7M
$-24.8M
Q3 25
$5.9M
Q2 25
$-5.4M
Q1 25
$6.4M
Q4 24
$-10.3M
Q3 24
$-5.3M
Q2 24
$27.4M
Q1 24
$-9.9M
Free Cash Flow
SLND
SLND
TWST
TWST
Q4 25
$9.3M
$-34.8M
Q3 25
$5.3M
Q2 25
$-6.5M
Q1 25
$4.6M
Q4 24
$-11.5M
Q3 24
$-7.3M
Q2 24
$26.3M
Q1 24
$-13.0M
FCF Margin
SLND
SLND
TWST
TWST
Q4 25
8.9%
-33.5%
Q3 25
2.5%
Q2 25
-3.0%
Q1 25
1.9%
Q4 24
-4.3%
Q3 24
-4.2%
Q2 24
10.5%
Q1 24
-4.5%
Capex Intensity
SLND
SLND
TWST
TWST
Q4 25
0.4%
9.6%
Q3 25
0.3%
Q2 25
0.5%
Q1 25
0.7%
Q4 24
0.5%
Q3 24
1.1%
Q2 24
0.4%
Q1 24
1.1%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

SLND
SLND

Civil$58.4M56%
Transportation$45.6M44%

TWST
TWST

Industrial Chemicals$37.2M36%
Diagnostics$35.3M34%
Food Or Agriculture$12.8M12%
Academic Research$12.2M12%
Health Care$6.1M6%

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