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Side-by-side financial comparison of Simulations Plus, Inc. (SLP) and Xtant Medical Holdings, Inc. (XTNT). Click either name above to swap in a different company.

Xtant Medical Holdings, Inc. is the larger business by last-quarter revenue ($32.4M vs $18.4M, roughly 1.8× Simulations Plus, Inc.). Simulations Plus, Inc. runs the higher net margin — 3.7% vs 0.2%, a 3.5% gap on every dollar of revenue. On growth, Xtant Medical Holdings, Inc. posted the faster year-over-year revenue change (2.7% vs -2.7%). Over the past eight quarters, Xtant Medical Holdings, Inc.'s revenue compounded faster (7.7% CAGR vs 0.3%).

Simulations Plus, Inc. develops absorption, distribution, metabolism, excretion, and toxicity (ADMET) modeling and simulation software for the pharmaceutical and biotechnology, industrial chemicals, cosmetics, food ingredients, and herbicide industries. In September 2014, the company acquired Cognigen Corporation, a provider of clinical trial data analysis and consulting services.

Xtant Medical Holdings, Inc. is a global medical technology company that develops, manufactures and markets orthobiologic products, neurosurgery devices, and regenerative medicine solutions for orthopedic and neurological care providers. It serves patients and medical institutions across North America, Europe and the Asia-Pacific, with core segments covering spinal surgery supplies and bone regeneration products.

SLP vs XTNT — Head-to-Head

Bigger by revenue
XTNT
XTNT
1.8× larger
XTNT
$32.4M
$18.4M
SLP
Growing faster (revenue YoY)
XTNT
XTNT
+5.3% gap
XTNT
2.7%
-2.7%
SLP
Higher net margin
SLP
SLP
3.5% more per $
SLP
3.7%
0.2%
XTNT
Faster 2-yr revenue CAGR
XTNT
XTNT
Annualised
XTNT
7.7%
0.3%
SLP

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
SLP
SLP
XTNT
XTNT
Revenue
$18.4M
$32.4M
Net Profit
$676.0K
$57.0K
Gross Margin
59.1%
54.9%
Operating Margin
3.9%
-2.9%
Net Margin
3.7%
0.2%
Revenue YoY
-2.7%
2.7%
Net Profit YoY
228.2%
101.8%
EPS (diluted)
$0.03
$0.00

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
SLP
SLP
XTNT
XTNT
Q4 25
$18.4M
$32.4M
Q3 25
$17.5M
$33.3M
Q2 25
$20.4M
$35.4M
Q1 25
$22.4M
$32.9M
Q4 24
$18.9M
$31.5M
Q3 24
$18.7M
$27.9M
Q2 24
$18.5M
$29.9M
Q1 24
$18.3M
$27.9M
Net Profit
SLP
SLP
XTNT
XTNT
Q4 25
$676.0K
$57.0K
Q3 25
$-681.0K
$1.3M
Q2 25
$-67.3M
$3.5M
Q1 25
$3.1M
$58.0K
Q4 24
$206.0K
$-3.2M
Q3 24
$843.0K
$-5.0M
Q2 24
$3.1M
$-3.9M
Q1 24
$4.0M
$-4.4M
Gross Margin
SLP
SLP
XTNT
XTNT
Q4 25
59.1%
54.9%
Q3 25
56.4%
66.1%
Q2 25
64.0%
68.6%
Q1 25
58.5%
61.5%
Q4 24
54.0%
50.9%
Q3 24
36.6%
58.4%
Q2 24
71.5%
62.1%
Q1 24
72.2%
62.1%
Operating Margin
SLP
SLP
XTNT
XTNT
Q4 25
3.9%
-2.9%
Q3 25
3.8%
7.6%
Q2 25
-364.5%
13.1%
Q1 25
12.1%
3.2%
Q4 24
0.7%
-6.0%
Q3 24
-6.2%
-13.5%
Q2 24
10.1%
-9.8%
Q1 24
24.3%
-12.4%
Net Margin
SLP
SLP
XTNT
XTNT
Q4 25
3.7%
0.2%
Q3 25
-3.9%
3.9%
Q2 25
-330.6%
10.0%
Q1 25
13.7%
0.2%
Q4 24
1.1%
-10.0%
Q3 24
4.5%
-18.0%
Q2 24
16.9%
-12.9%
Q1 24
22.0%
-15.8%
EPS (diluted)
SLP
SLP
XTNT
XTNT
Q4 25
$0.03
$0.00
Q3 25
$-0.03
$0.01
Q2 25
$-3.35
$0.02
Q1 25
$0.15
$0.00
Q4 24
$0.01
$-0.02
Q3 24
$0.04
$-0.04
Q2 24
$0.15
$-0.03
Q1 24
$0.20
$-0.03

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
SLP
SLP
XTNT
XTNT
Cash + ST InvestmentsLiquidity on hand
$35.7M
$17.1M
Total DebtLower is stronger
$11.0M
Stockholders' EquityBook value
$127.1M
$51.0M
Total Assets
$137.8M
$94.1M
Debt / EquityLower = less leverage
0.22×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
SLP
SLP
XTNT
XTNT
Q4 25
$35.7M
$17.1M
Q3 25
$32.4M
$10.4M
Q2 25
$28.4M
$6.9M
Q1 25
$21.4M
$5.0M
Q4 24
$18.2M
$6.2M
Q3 24
$20.3M
$6.6M
Q2 24
$119.0M
$5.4M
Q1 24
$108.5M
$4.5M
Total Debt
SLP
SLP
XTNT
XTNT
Q4 25
$11.0M
Q3 25
$17.4M
Q2 25
$22.3M
Q1 25
$22.2M
Q4 24
$22.0M
Q3 24
$19.1M
Q2 24
$21.8M
Q1 24
$16.8M
Stockholders' Equity
SLP
SLP
XTNT
XTNT
Q4 25
$127.1M
$51.0M
Q3 25
$124.8M
$50.4M
Q2 25
$123.8M
$48.5M
Q1 25
$189.5M
$43.9M
Q4 24
$184.7M
$43.0M
Q3 24
$182.4M
$45.7M
Q2 24
$180.9M
$45.0M
Q1 24
$177.0M
$47.7M
Total Assets
SLP
SLP
XTNT
XTNT
Q4 25
$137.8M
$94.1M
Q3 25
$131.9M
$106.3M
Q2 25
$134.4M
$103.5M
Q1 25
$201.4M
$95.8M
Q4 24
$196.9M
$93.8M
Q3 24
$196.6M
$98.9M
Q2 24
$192.7M
$95.6M
Q1 24
$194.0M
$93.9M
Debt / Equity
SLP
SLP
XTNT
XTNT
Q4 25
0.22×
Q3 25
0.35×
Q2 25
0.46×
Q1 25
0.51×
Q4 24
0.51×
Q3 24
0.42×
Q2 24
0.48×
Q1 24
0.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
SLP
SLP
XTNT
XTNT
Operating Cash FlowLast quarter
$4.2M
$5.4M
Free Cash FlowOCF − Capex
$5.0M
FCF MarginFCF / Revenue
15.4%
Capex IntensityCapex / Revenue
0.0%
1.2%
Cash ConversionOCF / Net Profit
6.26×
94.39×
TTM Free Cash FlowTrailing 4 quarters
$10.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
SLP
SLP
XTNT
XTNT
Q4 25
$4.2M
$5.4M
Q3 25
$5.6M
$4.6M
Q2 25
$8.1M
$1.3M
Q1 25
$5.7M
$1.3M
Q4 24
$-1.3M
$665.0K
Q3 24
$1.7M
$-1.7M
Q2 24
$5.7M
$-5.1M
Q1 24
$5.8M
$-5.8M
Free Cash Flow
SLP
SLP
XTNT
XTNT
Q4 25
$5.0M
Q3 25
$5.3M
$4.2M
Q2 25
$7.8M
$910.0K
Q1 25
$5.6M
$87.0K
Q4 24
$-1.4M
$-7.0K
Q3 24
$1.6M
$-3.8M
Q2 24
$5.6M
$-5.7M
Q1 24
$5.4M
$-6.5M
FCF Margin
SLP
SLP
XTNT
XTNT
Q4 25
15.4%
Q3 25
30.5%
12.6%
Q2 25
38.5%
2.6%
Q1 25
25.0%
0.3%
Q4 24
-7.2%
-0.0%
Q3 24
8.8%
-13.7%
Q2 24
30.0%
-18.9%
Q1 24
29.4%
-23.4%
Capex Intensity
SLP
SLP
XTNT
XTNT
Q4 25
0.0%
1.2%
Q3 25
1.5%
1.3%
Q2 25
1.5%
1.0%
Q1 25
0.3%
3.6%
Q4 24
0.5%
2.1%
Q3 24
0.1%
7.5%
Q2 24
0.6%
1.9%
Q1 24
2.4%
2.8%
Cash Conversion
SLP
SLP
XTNT
XTNT
Q4 25
6.26×
94.39×
Q3 25
3.53×
Q2 25
0.36×
Q1 25
1.84×
22.03×
Q4 24
-6.18×
Q3 24
1.97×
Q2 24
1.81×
Q1 24
1.44×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

SLP
SLP

Services Segment$9.5M52%
Development$7.2M39%
Discovery$1.3M7%

XTNT
XTNT

Orthobiologics$18.3M57%
Spinal Implant$9.4M29%
License Revenue$4.6M14%

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