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Side-by-side financial comparison of SELLAS Life Sciences Group, Inc. (SLS) and VYNE Therapeutics Inc. (VYNE). Click either name above to swap in a different company.

SELLAS Life Sciences Group, Inc. is the larger business by last-quarter revenue ($79.0K vs $69.0K, roughly 1.1× VYNE Therapeutics Inc.). VYNE Therapeutics Inc. runs the higher net margin — -8340.6% vs -12108.9%, a 3768.3% gap on every dollar of revenue.

SELLAS Life Sciences Group, Inc. is a late-stage clinical biopharmaceutical company focused on developing innovative cancer immunotherapies for patients with unmet medical needs. Its core pipeline targets both hematological malignancies and solid tumors, with lead product candidates addressing indications like acute myeloid leukemia, primarily serving markets across North America.

VYNE Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapies for dermatological conditions. Its product pipeline targets both common and underserved skin disorders, with primary operations and market reach across the United States, partnering with healthcare providers and specialty pharmacy networks to serve patients.

SLS vs VYNE — Head-to-Head

Bigger by revenue
SLS
SLS
1.1× larger
SLS
$79.0K
$69.0K
VYNE
Higher net margin
VYNE
VYNE
3768.3% more per $
VYNE
-8340.6%
-12108.9%
SLS

Income Statement — Q1 FY2024 vs Q2 FY2025

Metric
SLS
SLS
VYNE
VYNE
Revenue
$79.0K
$69.0K
Net Profit
$-9.6M
$-5.8M
Gross Margin
Operating Margin
-12208.9%
-10930.4%
Net Margin
-12108.9%
-8340.6%
Revenue YoY
-65.2%
Net Profit YoY
13.8%
38.8%
EPS (diluted)
$-0.21
$-0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
SLS
SLS
VYNE
VYNE
Q2 25
$69.0K
Q1 25
$202.0K
Q4 24
$84.0K
Q3 24
$121.0K
Q2 24
$198.0K
Q1 24
$79.0K
$98.0K
Q4 23
$76.0K
Q3 23
$114.0K
Net Profit
SLS
SLS
VYNE
VYNE
Q2 25
$-5.8M
Q1 25
$-8.6M
Q4 24
$-12.0M
Q3 24
$-12.2M
Q2 24
$-9.4M
Q1 24
$-9.6M
$-6.2M
Q4 23
$-6.2M
Q3 23
$-6.6M
Operating Margin
SLS
SLS
VYNE
VYNE
Q2 25
-10930.4%
Q1 25
-4553.0%
Q4 24
-15202.4%
Q3 24
-10819.0%
Q2 24
-5250.5%
Q1 24
-12208.9%
-7530.6%
Q4 23
-8988.2%
Q3 23
-5468.4%
Net Margin
SLS
SLS
VYNE
VYNE
Q2 25
-8340.6%
Q1 25
-4262.9%
Q4 24
-14311.9%
Q3 24
-10047.1%
Q2 24
-4750.5%
Q1 24
-12108.9%
-6376.5%
Q4 23
-8142.1%
Q3 23
-5775.4%
EPS (diluted)
SLS
SLS
VYNE
VYNE
Q2 25
$-0.13
Q1 25
$-0.20
Q4 24
$-0.27
Q3 24
$-0.29
Q2 24
$-0.22
Q1 24
$-0.21
$-0.15
Q4 23
$4.06
Q3 23
$-2.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
SLS
SLS
VYNE
VYNE
Cash + ST InvestmentsLiquidity on hand
$18.4M
$39.6M
Total DebtLower is stronger
$0
Stockholders' EquityBook value
$9.7M
$38.9M
Total Assets
$24.4M
$44.7M
Debt / EquityLower = less leverage
0.00×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
SLS
SLS
VYNE
VYNE
Q2 25
$39.6M
Q1 25
$50.3M
Q4 24
$61.5M
Q3 24
$70.2M
Q2 24
$78.1M
Q1 24
$18.4M
$86.0M
Q4 23
$93.3M
Q3 23
$15.4M
Total Debt
SLS
SLS
VYNE
VYNE
Q2 25
$0
Q1 25
$0
Q4 24
$0
Q3 24
$0
Q2 24
$0
Q1 24
$0
Q4 23
$0
Q3 23
$0
Stockholders' Equity
SLS
SLS
VYNE
VYNE
Q2 25
$38.9M
Q1 25
$44.1M
Q4 24
$52.1M
Q3 24
$63.5M
Q2 24
$74.9M
Q1 24
$9.7M
$83.4M
Q4 23
$88.7M
Q3 23
$11.5M
Total Assets
SLS
SLS
VYNE
VYNE
Q2 25
$44.7M
Q1 25
$56.4M
Q4 24
$66.9M
Q3 24
$76.2M
Q2 24
$86.6M
Q1 24
$24.4M
$91.7M
Q4 23
$97.7M
Q3 23
$19.3M
Debt / Equity
SLS
SLS
VYNE
VYNE
Q2 25
0.00×
Q1 25
0.00×
Q4 24
0.00×
Q3 24
0.00×
Q2 24
0.00×
Q1 24
0.00×
Q4 23
0.00×
Q3 23
0.00×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
SLS
SLS
VYNE
VYNE
Operating Cash FlowLast quarter
$-10.8M
$-10.8M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
SLS
SLS
VYNE
VYNE
Q2 25
$-10.8M
Q1 25
$-11.5M
Q4 24
$-9.0M
Q3 24
$-8.5M
Q2 24
$-8.5M
Q1 24
$-10.8M
$-8.0M
Q4 23
$-5.1M
Q3 23
$-5.2M

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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