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Side-by-side financial comparison of Semler Scientific, Inc. (SMLR) and UPEXI, INC. (UPXI). Click either name above to swap in a different company.

UPEXI, INC. is the larger business by last-quarter revenue ($8.1M vs $7.5M, roughly 1.1× Semler Scientific, Inc.). Semler Scientific, Inc. runs the higher net margin — 225.6% vs -2222.1%, a 2447.7% gap on every dollar of revenue. On growth, UPEXI, INC. posted the faster year-over-year revenue change (101.0% vs -44.6%). Over the past eight quarters, UPEXI, INC.'s revenue compounded faster (24.2% CAGR vs -29.5%).

Semler Scientific, Inc. develops, manufactures and distributes non-invasive medical diagnostic devices for chronic disease screening. Its flagship QuantaFlo system delivers fast, accurate peripheral arterial disease testing, serving hospitals, clinics, primary care practices and other healthcare providers primarily in the United States.

SMLR vs UPXI — Head-to-Head

Bigger by revenue
UPXI
UPXI
1.1× larger
UPXI
$8.1M
$7.5M
SMLR
Growing faster (revenue YoY)
UPXI
UPXI
+145.6% gap
UPXI
101.0%
-44.6%
SMLR
Higher net margin
SMLR
SMLR
2447.7% more per $
SMLR
225.6%
-2222.1%
UPXI
Faster 2-yr revenue CAGR
UPXI
UPXI
Annualised
UPXI
24.2%
-29.5%
SMLR

Income Statement — Q3 FY2025 vs Q2 FY2026

Metric
SMLR
SMLR
UPXI
UPXI
Revenue
$7.5M
$8.1M
Net Profit
$16.9M
$-178.9M
Gross Margin
91.5%
83.3%
Operating Margin
-72.0%
-2177.9%
Net Margin
225.6%
-2222.1%
Revenue YoY
-44.6%
101.0%
Net Profit YoY
201.3%
-13649.6%
EPS (diluted)
$1.07

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
SMLR
SMLR
UPXI
UPXI
Q4 25
$8.1M
Q3 25
$7.5M
$9.2M
Q2 25
$8.2M
$4.3M
Q1 25
$8.8M
$3.2M
Q4 24
$12.4M
$4.0M
Q3 24
$13.5M
$4.4M
Q2 24
$14.5M
$5.0M
Q1 24
$15.9M
$5.2M
Net Profit
SMLR
SMLR
UPXI
UPXI
Q4 25
$-178.9M
Q3 25
$16.9M
$66.7M
Q2 25
$66.9M
$-6.9M
Q1 25
$-64.7M
$-3.8M
Q4 24
$29.2M
$-1.3M
Q3 24
$5.6M
$-1.6M
Q2 24
$11.0K
$-15.7M
Q1 24
$6.1M
$-4.1M
Gross Margin
SMLR
SMLR
UPXI
UPXI
Q4 25
83.3%
Q3 25
91.5%
89.6%
Q2 25
91.0%
79.4%
Q1 25
89.4%
49.3%
Q4 24
91.1%
74.3%
Q3 24
91.4%
67.3%
Q2 24
91.3%
31.0%
Q1 24
92.2%
24.3%
Operating Margin
SMLR
SMLR
UPXI
UPXI
Q4 25
-2177.9%
Q3 25
-72.0%
Q2 25
-25.0%
-151.7%
Q1 25
-352.0%
-113.5%
Q4 24
28.5%
-26.8%
Q3 24
37.5%
-30.6%
Q2 24
37.0%
-265.2%
Q1 24
43.9%
-96.5%
Net Margin
SMLR
SMLR
UPXI
UPXI
Q4 25
-2222.1%
Q3 25
225.6%
722.4%
Q2 25
814.6%
-161.5%
Q1 25
-732.3%
-121.2%
Q4 24
235.3%
-32.5%
Q3 24
41.5%
-37.3%
Q2 24
0.1%
-312.4%
Q1 24
38.2%
-78.9%
EPS (diluted)
SMLR
SMLR
UPXI
UPXI
Q4 25
Q3 25
$1.07
$0.76
Q2 25
$5.04
$0.83
Q1 25
$-6.74
$-2.87
Q4 24
$3.63
$-1.24
Q3 24
$0.72
$1.55
Q2 24
$0.00
$-15.66
Q1 24
$0.78
$-4.03

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
SMLR
SMLR
UPXI
UPXI
Cash + ST InvestmentsLiquidity on hand
$10.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$459.7M
$48.7M
Total Assets
$596.7M
$271.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
SMLR
SMLR
UPXI
UPXI
Q4 25
Q3 25
$10.2M
Q2 25
$13.5M
Q1 25
$9.7M
Q4 24
$8.8M
Q3 24
$6.6M
Q2 24
$7.3M
Q1 24
$62.8M
Stockholders' Equity
SMLR
SMLR
UPXI
UPXI
Q4 25
$48.7M
Q3 25
$459.7M
$210.8M
Q2 25
$383.4M
$90.1M
Q1 25
$161.7M
$1.9M
Q4 24
$230.8M
$3.8M
Q3 24
$85.4M
$5.0M
Q2 24
$78.4M
$6.5M
Q1 24
$77.9M
$22.1M
Total Assets
SMLR
SMLR
UPXI
UPXI
Q4 25
$271.1M
Q3 25
$596.7M
$419.7M
Q2 25
$522.6M
$123.8M
Q1 25
$293.4M
$15.1M
Q4 24
$239.8M
$17.5M
Q3 24
$92.2M
$18.6M
Q2 24
$84.8M
$23.5M
Q1 24
$83.9M
$56.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
SMLR
SMLR
UPXI
UPXI
Operating Cash FlowLast quarter
$-33.0M
$-2.7M
Free Cash FlowOCF − Capex
$-2.7M
FCF MarginFCF / Revenue
-33.5%
Capex IntensityCapex / Revenue
0.2%
Cash ConversionOCF / Net Profit
-1.95×
TTM Free Cash FlowTrailing 4 quarters
$-22.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
SMLR
SMLR
UPXI
UPXI
Q4 25
$-2.7M
Q3 25
$-33.0M
$-9.8M
Q2 25
$514.0K
$-8.4M
Q1 25
$-1.9M
$-778.7K
Q4 24
$7.4M
$-1.4M
Q3 24
$6.4M
$-2.0M
Q2 24
$4.9M
$-101.4K
Q1 24
$5.6M
$783.5K
Free Cash Flow
SMLR
SMLR
UPXI
UPXI
Q4 25
$-2.7M
Q3 25
$-9.8M
Q2 25
$-8.8M
Q1 25
$-809.3K
Q4 24
$7.4M
Q3 24
$-2.1M
Q2 24
$4.9M
$-1.0M
Q1 24
$5.6M
$600.9K
FCF Margin
SMLR
SMLR
UPXI
UPXI
Q4 25
-33.5%
Q3 25
-106.0%
Q2 25
-205.4%
Q1 25
-25.6%
Q4 24
59.8%
Q3 24
-49.2%
Q2 24
33.8%
-20.5%
Q1 24
35.3%
11.5%
Capex Intensity
SMLR
SMLR
UPXI
UPXI
Q4 25
0.2%
Q3 25
0.2%
Q2 25
9.0%
Q1 25
1.0%
Q4 24
0.0%
0.0%
Q3 24
0.0%
3.8%
Q2 24
0.3%
18.5%
Q1 24
0.0%
3.5%
Cash Conversion
SMLR
SMLR
UPXI
UPXI
Q4 25
Q3 25
-1.95×
-0.15×
Q2 25
0.01×
Q1 25
Q4 24
0.25×
Q3 24
1.15×
Q2 24
448.55×
Q1 24
0.93×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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