vs

Side-by-side financial comparison of S&T BANCORP INC (STBA) and Twist Bioscience Corp (TWST). Click either name above to swap in a different company.

Twist Bioscience Corp is the larger business by last-quarter revenue ($103.7M vs $102.1M, roughly 1.0× S&T BANCORP INC). S&T BANCORP INC runs the higher net margin — 34.4% vs -29.4%, a 63.8% gap on every dollar of revenue.

U.S. Bancorp is an American multinational banking institution headquartered in Minneapolis, Minnesota and incorporated in Delaware. It is the 5th-largest bank in the United States as of 2025. As the largest bank in the Midwestern United States, it is considered systemically important by the Financial Stability Board. It is the parent company of its primary operating entity, U.S. Bank National Association, which does business as U.S. Bank. The company provides banking, investment, mortgage, tr...

Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.

STBA vs TWST — Head-to-Head

Bigger by revenue
TWST
TWST
1.0× larger
TWST
$103.7M
$102.1M
STBA
Higher net margin
STBA
STBA
63.8% more per $
STBA
34.4%
-29.4%
TWST

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
STBA
STBA
TWST
TWST
Revenue
$102.1M
$103.7M
Net Profit
$35.1M
$-30.5M
Gross Margin
52.0%
Operating Margin
-31.7%
Net Margin
34.4%
-29.4%
Revenue YoY
16.9%
Net Profit YoY
5.0%
3.4%
EPS (diluted)
$0.94
$-0.50

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
STBA
STBA
TWST
TWST
Q1 26
$102.1M
Q4 25
$105.3M
$103.7M
Q3 25
$103.0M
Q2 25
$100.1M
Q1 25
$93.8M
Q4 24
$94.3M
Q3 24
$96.4M
Q2 24
$96.9M
Net Profit
STBA
STBA
TWST
TWST
Q1 26
$35.1M
Q4 25
$34.0M
$-30.5M
Q3 25
$35.0M
Q2 25
$31.9M
Q1 25
$33.4M
Q4 24
$33.1M
Q3 24
$32.6M
Q2 24
$34.4M
Gross Margin
STBA
STBA
TWST
TWST
Q1 26
Q4 25
52.0%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Operating Margin
STBA
STBA
TWST
TWST
Q1 26
Q4 25
40.3%
-31.7%
Q3 25
42.6%
Q2 25
40.0%
Q1 25
44.5%
Q4 24
43.8%
Q3 24
43.0%
Q2 24
44.2%
Net Margin
STBA
STBA
TWST
TWST
Q1 26
34.4%
Q4 25
32.3%
-29.4%
Q3 25
33.9%
Q2 25
31.9%
Q1 25
35.6%
Q4 24
35.1%
Q3 24
33.8%
Q2 24
35.5%
EPS (diluted)
STBA
STBA
TWST
TWST
Q1 26
$0.94
Q4 25
$0.88
$-0.50
Q3 25
$0.91
Q2 25
$0.83
Q1 25
$0.87
Q4 24
$0.86
Q3 24
$0.85
Q2 24
$0.89

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
STBA
STBA
TWST
TWST
Cash + ST InvestmentsLiquidity on hand
$197.9M
Total DebtLower is stronger
$100.8M
Stockholders' EquityBook value
$1.4B
$456.1M
Total Assets
$9.9B
$638.1M
Debt / EquityLower = less leverage
0.07×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
STBA
STBA
TWST
TWST
Q1 26
Q4 25
$163.4M
$197.9M
Q3 25
$196.2M
Q2 25
$203.1M
Q1 25
$211.8M
Q4 24
$244.8M
Q3 24
$228.1M
Q2 24
$246.3M
Total Debt
STBA
STBA
TWST
TWST
Q1 26
$100.8M
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Stockholders' Equity
STBA
STBA
TWST
TWST
Q1 26
$1.4B
Q4 25
$1.5B
$456.1M
Q3 25
$1.5B
Q2 25
$1.4B
Q1 25
$1.4B
Q4 24
$1.4B
Q3 24
$1.4B
Q2 24
$1.3B
Total Assets
STBA
STBA
TWST
TWST
Q1 26
$9.9B
Q4 25
$9.9B
$638.1M
Q3 25
$9.8B
Q2 25
$9.8B
Q1 25
$9.7B
Q4 24
$9.7B
Q3 24
$9.6B
Q2 24
$9.6B
Debt / Equity
STBA
STBA
TWST
TWST
Q1 26
0.07×
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
STBA
STBA
TWST
TWST
Operating Cash FlowLast quarter
$-24.8M
Free Cash FlowOCF − Capex
$-34.8M
FCF MarginFCF / Revenue
-33.5%
Capex IntensityCapex / Revenue
9.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
STBA
STBA
TWST
TWST
Q1 26
Q4 25
$133.6M
$-24.8M
Q3 25
$40.5M
Q2 25
$28.3M
Q1 25
$28.7M
Q4 24
$173.4M
Q3 24
$27.6M
Q2 24
$44.7M
Free Cash Flow
STBA
STBA
TWST
TWST
Q1 26
Q4 25
$128.8M
$-34.8M
Q3 25
$39.9M
Q2 25
$27.1M
Q1 25
$27.0M
Q4 24
$170.4M
Q3 24
$26.9M
Q2 24
$43.9M
FCF Margin
STBA
STBA
TWST
TWST
Q1 26
Q4 25
122.4%
-33.5%
Q3 25
38.7%
Q2 25
27.1%
Q1 25
28.8%
Q4 24
180.7%
Q3 24
28.0%
Q2 24
45.3%
Capex Intensity
STBA
STBA
TWST
TWST
Q1 26
Q4 25
4.5%
9.6%
Q3 25
0.6%
Q2 25
1.2%
Q1 25
1.8%
Q4 24
3.1%
Q3 24
0.7%
Q2 24
0.9%
Cash Conversion
STBA
STBA
TWST
TWST
Q1 26
Q4 25
3.93×
Q3 25
1.16×
Q2 25
0.89×
Q1 25
0.86×
Q4 24
5.24×
Q3 24
0.85×
Q2 24
1.30×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

STBA
STBA

Net Interest Income$88.4M87%
Noninterest Income$13.6M13%

TWST
TWST

Industrial Chemicals$37.2M36%
Diagnostics$35.3M34%
Food Or Agriculture$12.8M12%
Academic Research$12.2M12%
Health Care$6.1M6%

Related Comparisons