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Side-by-side financial comparison of STEM, INC. (STEM) and X4 Pharmaceuticals, Inc (XFOR). Click either name above to swap in a different company.

STEM, INC. is the larger business by last-quarter revenue ($47.1M vs $28.8M, roughly 1.6× X4 Pharmaceuticals, Inc). X4 Pharmaceuticals, Inc runs the higher net margin — 1.0% vs -33.9%, a 34.9% gap on every dollar of revenue.

StemCells, Inc. is a public biopharmaceutical company headquartered in Newark, California, that is developing purified human neural stem cells (HuCNS-SCs) in the hopes of treating central nervous system disorders and paralysis. StemCells' HuCNS-SCs have the ability to differentiate into the three main types of cells found in the central nervous system: neurons, astrocytes and oligodendrocytes.

X4 Pharmaceuticals, Inc. is a clinical-stage biotechnology company focused on developing novel targeted therapies for rare immunological diseases and oncology indications with high unmet medical needs. It operates primarily across the U.S. and European markets, with a lead pipeline candidate for WHIM syndrome and multiple other preclinical and clinical assets for immune disorders and cancer.

STEM vs XFOR — Head-to-Head

Bigger by revenue
STEM
STEM
1.6× larger
STEM
$47.1M
$28.8M
XFOR
Higher net margin
XFOR
XFOR
34.9% more per $
XFOR
1.0%
-33.9%
STEM

Income Statement — Q4 FY2025 vs Q1 FY2025

Metric
STEM
STEM
XFOR
XFOR
Revenue
$47.1M
$28.8M
Net Profit
$-16.0M
$282.0K
Gross Margin
48.9%
83.6%
Operating Margin
-17.7%
-32.8%
Net Margin
-33.9%
1.0%
Revenue YoY
-15.6%
Net Profit YoY
68.8%
100.5%
EPS (diluted)
$-4.40
$0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
STEM
STEM
XFOR
XFOR
Q4 25
$47.1M
Q3 25
$38.2M
Q2 25
$38.4M
Q1 25
$32.5M
$28.8M
Q4 24
$55.8M
Q3 24
$29.3M
Q2 24
$34.0M
Q1 24
$25.5M
$0
Net Profit
STEM
STEM
XFOR
XFOR
Q4 25
$-16.0M
Q3 25
$-23.8M
Q2 25
$202.5M
Q1 25
$-25.0M
$282.0K
Q4 24
$-51.1M
Q3 24
$-148.3M
Q2 24
$-582.3M
Q1 24
$-72.3M
$-51.8M
Gross Margin
STEM
STEM
XFOR
XFOR
Q4 25
48.9%
Q3 25
35.5%
Q2 25
33.4%
Q1 25
32.4%
83.6%
Q4 24
-4.4%
Q3 24
21.2%
Q2 24
27.6%
Q1 24
-95.0%
Operating Margin
STEM
STEM
XFOR
XFOR
Q4 25
-17.7%
Q3 25
-33.6%
Q2 25
-34.8%
Q1 25
-65.0%
-32.8%
Q4 24
-84.4%
Q3 24
-493.2%
Q2 24
-1705.5%
Q1 24
-267.0%
Net Margin
STEM
STEM
XFOR
XFOR
Q4 25
-33.9%
Q3 25
-62.2%
Q2 25
527.8%
Q1 25
-76.9%
1.0%
Q4 24
-91.6%
Q3 24
-506.3%
Q2 24
-1712.6%
Q1 24
-283.9%
EPS (diluted)
STEM
STEM
XFOR
XFOR
Q4 25
$-4.40
Q3 25
$-2.84
Q2 25
$-1.79
Q1 25
$-0.15
$0.04
Q4 24
$-15.29
Q3 24
$-18.24
Q2 24
$-71.81
Q1 24
$-0.46
$-7.77

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
STEM
STEM
XFOR
XFOR
Cash + ST InvestmentsLiquidity on hand
$48.9M
$40.3M
Total DebtLower is stronger
$75.0M
Stockholders' EquityBook value
$-249.4M
$22.9M
Total Assets
$308.9M
$130.0M
Debt / EquityLower = less leverage
3.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
STEM
STEM
XFOR
XFOR
Q4 25
$48.9M
Q3 25
$43.1M
Q2 25
$40.8M
Q1 25
$58.6M
$40.3M
Q4 24
$56.3M
Q3 24
$75.4M
Q2 24
$89.6M
Q1 24
$112.8M
$60.5M
Total Debt
STEM
STEM
XFOR
XFOR
Q4 25
Q3 25
Q2 25
Q1 25
$75.0M
Q4 24
Q3 24
Q2 24
Q1 24
$55.0M
Stockholders' Equity
STEM
STEM
XFOR
XFOR
Q4 25
$-249.4M
Q3 25
$-235.7M
Q2 25
$-214.1M
Q1 25
$-417.5M
$22.9M
Q4 24
$-398.4M
Q3 24
$-344.1M
Q2 24
$-203.2M
Q1 24
$371.6M
$1.0M
Total Assets
STEM
STEM
XFOR
XFOR
Q4 25
$308.9M
Q3 25
$362.6M
Q2 25
$379.2M
Q1 25
$405.1M
$130.0M
Q4 24
$437.4M
Q3 24
$537.8M
Q2 24
$691.5M
Q1 24
$1.3B
$112.2M
Debt / Equity
STEM
STEM
XFOR
XFOR
Q4 25
Q3 25
Q2 25
Q1 25
3.27×
Q4 24
Q3 24
Q2 24
Q1 24
53.09×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
STEM
STEM
XFOR
XFOR
Operating Cash FlowLast quarter
$8.2M
$-12.4M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
-43.86×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
STEM
STEM
XFOR
XFOR
Q4 25
$8.2M
Q3 25
$11.4M
Q2 25
$-21.3M
Q1 25
$8.5M
$-12.4M
Q4 24
$-14.7M
Q3 24
$-9.4M
Q2 24
$-11.9M
Q1 24
$-621.0K
$-33.6M
Free Cash Flow
STEM
STEM
XFOR
XFOR
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
$-33.7M
Capex Intensity
STEM
STEM
XFOR
XFOR
Q4 25
Q3 25
Q2 25
Q1 25
0.0%
Q4 24
Q3 24
Q2 24
Q1 24
Cash Conversion
STEM
STEM
XFOR
XFOR
Q4 25
Q3 25
Q2 25
-0.11×
Q1 25
-43.86×
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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