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Side-by-side financial comparison of SUTRO BIOPHARMA, INC. (STRO) and UPEXI, INC. (UPXI). Click either name above to swap in a different company.

SUTRO BIOPHARMA, INC. is the larger business by last-quarter revenue ($11.6M vs $8.1M, roughly 1.4× UPEXI, INC.). On growth, UPEXI, INC. posted the faster year-over-year revenue change (101.0% vs -21.4%). Over the past eight quarters, UPEXI, INC.'s revenue compounded faster (24.2% CAGR vs -5.4%).

Sutro Biopharma, Inc. is a publicly traded biotechnology company headquartered in South San Francisco, California focused on clinical-stage drug discovery, development and manufacturing. Using a proprietary cell-free protein synthesis platform, Sutro is working on oncology therapeutics using protein engineering and rational design. Founded in 2003 under the name Fundamental Applied Biology, the company name changed to Sutro Biopharma in 2009. William Newell, CEO as of 2024, joined Sutro in Ja...

STRO vs UPXI — Head-to-Head

Bigger by revenue
STRO
STRO
1.4× larger
STRO
$11.6M
$8.1M
UPXI
Growing faster (revenue YoY)
UPXI
UPXI
+122.4% gap
UPXI
101.0%
-21.4%
STRO
Faster 2-yr revenue CAGR
UPXI
UPXI
Annualised
UPXI
24.2%
-5.4%
STRO

Income Statement — Q4 FY2025 vs Q2 FY2026

Metric
STRO
STRO
UPXI
UPXI
Revenue
$11.6M
$8.1M
Net Profit
$-178.9M
Gross Margin
83.3%
Operating Margin
-2177.9%
Net Margin
-2222.1%
Revenue YoY
-21.4%
101.0%
Net Profit YoY
35.4%
-13649.6%
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
STRO
STRO
UPXI
UPXI
Q4 25
$11.6M
$8.1M
Q3 25
$9.7M
$9.2M
Q2 25
$63.7M
$4.3M
Q1 25
$17.4M
$3.2M
Q4 24
$14.8M
$4.0M
Q3 24
$8.5M
$4.4M
Q2 24
$25.7M
$5.0M
Q1 24
$13.0M
$5.2M
Net Profit
STRO
STRO
UPXI
UPXI
Q4 25
$-178.9M
Q3 25
$-56.9M
$66.7M
Q2 25
$-11.5M
$-6.9M
Q1 25
$-76.0M
$-3.8M
Q4 24
$-72.4M
$-1.3M
Q3 24
$-48.8M
$-1.6M
Q2 24
$-48.0M
$-15.7M
Q1 24
$-58.2M
$-4.1M
Gross Margin
STRO
STRO
UPXI
UPXI
Q4 25
83.3%
Q3 25
89.6%
Q2 25
79.4%
Q1 25
49.3%
Q4 24
74.3%
Q3 24
67.3%
Q2 24
31.0%
Q1 24
24.3%
Operating Margin
STRO
STRO
UPXI
UPXI
Q4 25
-2177.9%
Q3 25
-499.9%
Q2 25
-5.2%
-151.7%
Q1 25
-393.8%
-113.5%
Q4 24
-440.7%
-26.8%
Q3 24
-797.2%
-30.6%
Q2 24
-189.4%
-265.2%
Q1 24
-435.0%
-96.5%
Net Margin
STRO
STRO
UPXI
UPXI
Q4 25
-2222.1%
Q3 25
-586.6%
722.4%
Q2 25
-18.0%
-161.5%
Q1 25
-436.6%
-121.2%
Q4 24
-489.2%
-32.5%
Q3 24
-572.6%
-37.3%
Q2 24
-186.8%
-312.4%
Q1 24
-447.5%
-78.9%
EPS (diluted)
STRO
STRO
UPXI
UPXI
Q4 25
Q3 25
$-0.67
$0.76
Q2 25
$-0.14
$0.83
Q1 25
$-0.91
$-2.87
Q4 24
$-27.63
$-1.24
Q3 24
$-0.59
$1.55
Q2 24
$-0.59
$-15.66
Q1 24
$-0.59
$-4.03

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
STRO
STRO
UPXI
UPXI
Cash + ST InvestmentsLiquidity on hand
$141.4M
Total DebtLower is stronger
Stockholders' EquityBook value
$-132.5M
$48.7M
Total Assets
$173.8M
$271.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
STRO
STRO
UPXI
UPXI
Q4 25
$141.4M
Q3 25
$167.6M
Q2 25
$205.1M
Q1 25
$249.0M
Q4 24
$316.9M
Q3 24
$388.3M
Q2 24
$375.6M
Q1 24
$267.6M
Stockholders' Equity
STRO
STRO
UPXI
UPXI
Q4 25
$-132.5M
$48.7M
Q3 25
$-87.3M
$210.8M
Q2 25
$-32.1M
$90.1M
Q1 25
$-25.8M
$1.9M
Q4 24
$44.6M
$3.8M
Q3 24
$111.2M
$5.0M
Q2 24
$152.2M
$6.5M
Q1 24
$98.0M
$22.1M
Total Assets
STRO
STRO
UPXI
UPXI
Q4 25
$173.8M
$271.1M
Q3 25
$209.7M
$419.7M
Q2 25
$262.4M
$123.8M
Q1 25
$321.4M
$15.1M
Q4 24
$387.2M
$17.5M
Q3 24
$451.8M
$18.6M
Q2 24
$489.0M
$23.5M
Q1 24
$403.4M
$56.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
STRO
STRO
UPXI
UPXI
Operating Cash FlowLast quarter
$-177.2M
$-2.7M
Free Cash FlowOCF − Capex
$-2.7M
FCF MarginFCF / Revenue
-33.5%
Capex IntensityCapex / Revenue
0.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-22.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
STRO
STRO
UPXI
UPXI
Q4 25
$-177.2M
$-2.7M
Q3 25
$-38.2M
$-9.8M
Q2 25
$-44.7M
$-8.4M
Q1 25
$-67.9M
$-778.7K
Q4 24
$-71.7M
$-1.4M
Q3 24
$-64.5M
$-2.0M
Q2 24
$9.5M
$-101.4K
Q1 24
$-64.7M
$783.5K
Free Cash Flow
STRO
STRO
UPXI
UPXI
Q4 25
$-2.7M
Q3 25
$-9.8M
Q2 25
$-8.8M
Q1 25
$-809.3K
Q4 24
Q3 24
$-2.1M
Q2 24
$-1.0M
Q1 24
$600.9K
FCF Margin
STRO
STRO
UPXI
UPXI
Q4 25
-33.5%
Q3 25
-106.0%
Q2 25
-205.4%
Q1 25
-25.6%
Q4 24
Q3 24
-49.2%
Q2 24
-20.5%
Q1 24
11.5%
Capex Intensity
STRO
STRO
UPXI
UPXI
Q4 25
0.2%
Q3 25
0.2%
Q2 25
9.0%
Q1 25
1.0%
Q4 24
0.0%
Q3 24
3.8%
Q2 24
18.5%
Q1 24
3.5%
Cash Conversion
STRO
STRO
UPXI
UPXI
Q4 25
Q3 25
-0.15×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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