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Side-by-side financial comparison of Synchrony Financial (SYF) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Synchrony Financial is the larger business by last-quarter revenue ($4.8B vs $3.2B, roughly 1.5× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 15.8%, a 21.6% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 3.7%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs 4.0%).

Synchrony Financial is an American consumer financial services company with its headquarters in Stamford, Connecticut, United States. The company offers consumer financing products, including credit, promotional financing and loyalty programs, installment lending to industries and consumers through Synchrony Bank, its wholly owned online bank subsidiary.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

SYF vs VRTX — Head-to-Head

Bigger by revenue
SYF
SYF
1.5× larger
SYF
$4.8B
$3.2B
VRTX
Growing faster (revenue YoY)
VRTX
VRTX
+5.9% gap
VRTX
9.5%
3.7%
SYF
Higher net margin
VRTX
VRTX
21.6% more per $
VRTX
37.3%
15.8%
SYF
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
4.0%
SYF

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
SYF
SYF
VRTX
VRTX
Revenue
$4.8B
$3.2B
Net Profit
$751.0M
$1.2B
Gross Margin
85.4%
Operating Margin
20.0%
37.8%
Net Margin
15.8%
37.3%
Revenue YoY
3.7%
9.5%
Net Profit YoY
-3.0%
30.5%
EPS (diluted)
$2.03
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
SYF
SYF
VRTX
VRTX
Q4 25
$4.8B
$3.2B
Q3 25
$4.7B
$3.1B
Q2 25
$4.5B
$3.0B
Q1 25
$4.5B
$2.8B
Q4 24
$4.6B
$2.9B
Q3 24
$4.6B
$2.8B
Q2 24
$4.4B
$2.6B
Q1 24
$4.4B
$2.7B
Net Profit
SYF
SYF
VRTX
VRTX
Q4 25
$751.0M
$1.2B
Q3 25
$1.1B
$1.1B
Q2 25
$967.0M
$1.0B
Q1 25
$757.0M
$646.3M
Q4 24
$774.0M
$913.0M
Q3 24
$789.0M
$1.0B
Q2 24
$643.0M
$-3.6B
Q1 24
$1.3B
$1.1B
Gross Margin
SYF
SYF
VRTX
VRTX
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Q1 24
87.3%
Operating Margin
SYF
SYF
VRTX
VRTX
Q4 25
20.0%
37.8%
Q3 25
30.3%
38.6%
Q2 25
27.8%
38.8%
Q1 25
22.0%
22.7%
Q4 24
21.2%
35.2%
Q3 24
22.3%
40.3%
Q2 24
19.2%
-132.9%
Q1 24
38.8%
42.4%
Net Margin
SYF
SYF
VRTX
VRTX
Q4 25
15.8%
37.3%
Q3 25
22.8%
35.2%
Q2 25
21.4%
34.8%
Q1 25
17.0%
23.3%
Q4 24
16.9%
31.4%
Q3 24
17.1%
37.7%
Q2 24
14.6%
-135.8%
Q1 24
29.4%
40.9%
EPS (diluted)
SYF
SYF
VRTX
VRTX
Q4 25
$2.03
$4.64
Q3 25
$2.86
$4.20
Q2 25
$2.50
$3.99
Q1 25
$1.89
$2.49
Q4 24
$1.92
$3.62
Q3 24
$1.94
$4.01
Q2 24
$1.55
$-13.92
Q1 24
$3.14
$4.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
SYF
SYF
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$15.0B
$6.6B
Total DebtLower is stronger
$15.2B
Stockholders' EquityBook value
$16.8B
$18.7B
Total Assets
$119.1B
$25.6B
Debt / EquityLower = less leverage
0.91×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
SYF
SYF
VRTX
VRTX
Q4 25
$15.0B
$6.6B
Q3 25
$16.2B
$6.3B
Q2 25
$19.5B
$6.4B
Q1 25
$21.6B
$6.2B
Q4 24
$14.7B
$6.1B
Q3 24
$17.9B
$6.5B
Q2 24
$18.6B
$5.8B
Q1 24
$20.0B
$10.2B
Total Debt
SYF
SYF
VRTX
VRTX
Q4 25
$15.2B
Q3 25
$14.4B
Q2 25
$16.0B
Q1 25
$17.0B
Q4 24
$15.5B
Q3 24
$15.6B
Q2 24
$15.6B
Q1 24
$16.1B
Stockholders' Equity
SYF
SYF
VRTX
VRTX
Q4 25
$16.8B
$18.7B
Q3 25
$17.1B
$17.3B
Q2 25
$17.0B
$17.2B
Q1 25
$16.6B
$16.5B
Q4 24
$16.6B
$16.4B
Q3 24
$16.0B
$15.6B
Q2 24
$15.5B
$14.8B
Q1 24
$15.3B
$18.5B
Total Assets
SYF
SYF
VRTX
VRTX
Q4 25
$119.1B
$25.6B
Q3 25
$117.0B
$24.9B
Q2 25
$120.5B
$24.0B
Q1 25
$122.0B
$22.9B
Q4 24
$119.5B
$22.5B
Q3 24
$119.2B
$22.2B
Q2 24
$120.5B
$20.1B
Q1 24
$121.2B
$23.9B
Debt / Equity
SYF
SYF
VRTX
VRTX
Q4 25
0.91×
Q3 25
0.85×
Q2 25
0.94×
Q1 25
1.03×
Q4 24
0.93×
Q3 24
0.98×
Q2 24
1.01×
Q1 24
1.06×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
SYF
SYF
VRTX
VRTX
Operating Cash FlowLast quarter
$2.5B
$498.0M
Free Cash FlowOCF − Capex
$348.6M
FCF MarginFCF / Revenue
10.9%
Capex IntensityCapex / Revenue
4.7%
Cash ConversionOCF / Net Profit
3.27×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
SYF
SYF
VRTX
VRTX
Q4 25
$2.5B
$498.0M
Q3 25
$2.6B
$1.2B
Q2 25
$2.6B
$1.1B
Q1 25
$2.2B
$818.9M
Q4 24
$2.4B
$584.6M
Q3 24
$2.8B
$1.4B
Q2 24
$2.5B
$-3.8B
Q1 24
$2.2B
$1.3B
Free Cash Flow
SYF
SYF
VRTX
VRTX
Q4 25
$348.6M
Q3 25
$1.1B
Q2 25
$927.4M
Q1 25
$778.2M
Q4 24
$492.0M
Q3 24
$1.3B
Q2 24
$-3.8B
Q1 24
$1.2B
FCF Margin
SYF
SYF
VRTX
VRTX
Q4 25
10.9%
Q3 25
37.0%
Q2 25
31.3%
Q1 25
28.1%
Q4 24
16.9%
Q3 24
47.0%
Q2 24
-144.5%
Q1 24
46.0%
Capex Intensity
SYF
SYF
VRTX
VRTX
Q4 25
4.7%
Q3 25
3.3%
Q2 25
4.9%
Q1 25
1.5%
Q4 24
3.2%
Q3 24
2.4%
Q2 24
2.6%
Q1 24
2.5%
Cash Conversion
SYF
SYF
VRTX
VRTX
Q4 25
3.27×
0.42×
Q3 25
2.45×
1.15×
Q2 25
2.65×
1.04×
Q1 25
2.91×
1.27×
Q4 24
3.04×
0.64×
Q3 24
3.50×
1.31×
Q2 24
3.86×
Q1 24
1.74×
1.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

SYF
SYF

Segment breakdown not available.

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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