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Side-by-side financial comparison of Vertex Pharmaceuticals (VRTX) and Williams-Sonoma, Inc. (WSM). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $1.9B, roughly 1.7× Williams-Sonoma, Inc.). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 12.8%, a 24.5% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 4.6%). Vertex Pharmaceuticals produced more free cash flow last quarter ($348.6M vs $248.1M). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs -9.1%).

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

Williams Sonoma is an American retailer of cookware, appliances, and home furnishings. It is owned by Williams-Sonoma, Inc., and was founded by Charles E. (Chuck) Williams in 1956.

VRTX vs WSM — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.7× larger
VRTX
$3.2B
$1.9B
WSM
Growing faster (revenue YoY)
VRTX
VRTX
+5.0% gap
VRTX
9.5%
4.6%
WSM
Higher net margin
VRTX
VRTX
24.5% more per $
VRTX
37.3%
12.8%
WSM
More free cash flow
VRTX
VRTX
$100.5M more FCF
VRTX
$348.6M
$248.1M
WSM
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
-9.1%
WSM

Income Statement — Q4 FY2025 vs Q3 FY2026

Metric
VRTX
VRTX
WSM
WSM
Revenue
$3.2B
$1.9B
Net Profit
$1.2B
$241.6M
Gross Margin
85.4%
46.1%
Operating Margin
37.8%
17.0%
Net Margin
37.3%
12.8%
Revenue YoY
9.5%
4.6%
Net Profit YoY
30.5%
-3.0%
EPS (diluted)
$4.64
$1.96

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
VRTX
VRTX
WSM
WSM
Q4 25
$3.2B
$1.9B
Q3 25
$3.1B
$1.8B
Q2 25
$3.0B
$1.7B
Q1 25
$2.8B
$2.5B
Q4 24
$2.9B
$1.8B
Q3 24
$2.8B
$1.8B
Q2 24
$2.6B
$1.7B
Q1 24
$2.7B
$2.3B
Net Profit
VRTX
VRTX
WSM
WSM
Q4 25
$1.2B
$241.6M
Q3 25
$1.1B
$247.6M
Q2 25
$1.0B
$231.3M
Q1 25
$646.3M
$384.9M
Q4 24
$913.0M
$249.0M
Q3 24
$1.0B
$225.7M
Q2 24
$-3.6B
$265.7M
Q1 24
$1.1B
$354.4M
Gross Margin
VRTX
VRTX
WSM
WSM
Q4 25
85.4%
46.1%
Q3 25
86.5%
47.1%
Q2 25
86.3%
44.3%
Q1 25
86.9%
45.2%
Q4 24
85.5%
46.7%
Q3 24
85.8%
46.2%
Q2 24
85.9%
48.3%
Q1 24
87.3%
46.0%
Operating Margin
VRTX
VRTX
WSM
WSM
Q4 25
37.8%
17.0%
Q3 25
38.6%
17.9%
Q2 25
38.8%
16.8%
Q1 25
22.7%
20.1%
Q4 24
35.2%
17.8%
Q3 24
40.3%
16.2%
Q2 24
-132.9%
19.5%
Q1 24
42.4%
20.1%
Net Margin
VRTX
VRTX
WSM
WSM
Q4 25
37.3%
12.8%
Q3 25
35.2%
13.5%
Q2 25
34.8%
13.4%
Q1 25
23.3%
15.6%
Q4 24
31.4%
13.8%
Q3 24
37.7%
12.6%
Q2 24
-135.8%
16.0%
Q1 24
40.9%
15.6%
EPS (diluted)
VRTX
VRTX
WSM
WSM
Q4 25
$4.64
$1.96
Q3 25
$4.20
$2.00
Q2 25
$3.99
$1.85
Q1 25
$2.49
$1.02
Q4 24
$3.62
$1.96
Q3 24
$4.01
$1.74
Q2 24
$-13.92
$4.07
Q1 24
$4.21
$5.42

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
VRTX
VRTX
WSM
WSM
Cash + ST InvestmentsLiquidity on hand
$6.6B
$884.7M
Total DebtLower is stronger
Stockholders' EquityBook value
$18.7B
$2.1B
Total Assets
$25.6B
$5.3B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
VRTX
VRTX
WSM
WSM
Q4 25
$6.6B
$884.7M
Q3 25
$6.3B
$985.8M
Q2 25
$6.4B
$1.0B
Q1 25
$6.2B
$1.2B
Q4 24
$6.1B
$826.8M
Q3 24
$6.5B
$1.3B
Q2 24
$5.8B
$1.3B
Q1 24
$10.2B
$1.3B
Stockholders' Equity
VRTX
VRTX
WSM
WSM
Q4 25
$18.7B
$2.1B
Q3 25
$17.3B
$2.1B
Q2 25
$17.2B
$2.2B
Q1 25
$16.5B
$2.1B
Q4 24
$16.4B
$1.9B
Q3 24
$15.6B
$2.3B
Q2 24
$14.8B
$2.2B
Q1 24
$18.5B
$2.1B
Total Assets
VRTX
VRTX
WSM
WSM
Q4 25
$25.6B
$5.3B
Q3 25
$24.9B
$5.2B
Q2 25
$24.0B
$5.2B
Q1 25
$22.9B
$5.3B
Q4 24
$22.5B
$5.0B
Q3 24
$22.2B
$5.2B
Q2 24
$20.1B
$5.2B
Q1 24
$23.9B
$5.3B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
VRTX
VRTX
WSM
WSM
Operating Cash FlowLast quarter
$498.0M
$316.3M
Free Cash FlowOCF − Capex
$348.6M
$248.1M
FCF MarginFCF / Revenue
10.9%
13.2%
Capex IntensityCapex / Revenue
4.7%
3.6%
Cash ConversionOCF / Net Profit
0.42×
1.31×
TTM Free Cash FlowTrailing 4 quarters
$3.2B
$1.1B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
VRTX
VRTX
WSM
WSM
Q4 25
$498.0M
$316.3M
Q3 25
$1.2B
$282.7M
Q2 25
$1.1B
$118.9M
Q1 25
$818.9M
$633.5M
Q4 24
$584.6M
$253.5M
Q3 24
$1.4B
$246.5M
Q2 24
$-3.8B
$226.8M
Q1 24
$1.3B
$674.9M
Free Cash Flow
VRTX
VRTX
WSM
WSM
Q4 25
$348.6M
$248.1M
Q3 25
$1.1B
$230.7M
Q2 25
$927.4M
$60.7M
Q1 25
$778.2M
$566.3M
Q4 24
$492.0M
$170.1M
Q3 24
$1.3B
$215.1M
Q2 24
$-3.8B
$187.3M
Q1 24
$1.2B
$621.2M
FCF Margin
VRTX
VRTX
WSM
WSM
Q4 25
10.9%
13.2%
Q3 25
37.0%
12.6%
Q2 25
31.3%
3.5%
Q1 25
28.1%
23.0%
Q4 24
16.9%
9.4%
Q3 24
47.0%
12.0%
Q2 24
-144.5%
11.3%
Q1 24
46.0%
27.3%
Capex Intensity
VRTX
VRTX
WSM
WSM
Q4 25
4.7%
3.6%
Q3 25
3.3%
2.8%
Q2 25
4.9%
3.4%
Q1 25
1.5%
2.7%
Q4 24
3.2%
4.6%
Q3 24
2.4%
1.8%
Q2 24
2.6%
2.4%
Q1 24
2.5%
2.4%
Cash Conversion
VRTX
VRTX
WSM
WSM
Q4 25
0.42×
1.31×
Q3 25
1.15×
1.14×
Q2 25
1.04×
0.51×
Q1 25
1.27×
1.65×
Q4 24
0.64×
1.02×
Q3 24
1.31×
1.09×
Q2 24
0.85×
Q1 24
1.19×
1.90×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

WSM
WSM

Segment breakdown not available.

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