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Guardant Health, Inc.

Guardant Health, Inc.GHEarnings & Financial Report

Nasdaq · biotechnology

Guardant Health, Inc. is an American biotechnology company based in Palo Alto, California. Co-founders Helmy Eltoukhy and AmirAli Talasaz serve as co-chief executive officers.

GH Q4 2025 Key Financial Metrics

売上高

$281.3M

粗利益

$181.8M

営業利益

$-120.8M

純利益

$-128.5M

粗利益率

64.6%

営業利益率

-43.0%

純利益率

-45.7%

前年比成長

39.4%

EPS

$-1.01

資金フロー

Guardant Health, Inc. Q4 2025 Financial Summary

Guardant Health, Inc. reported revenue of $281.3M (up 39.4% YoY) for Q4 2025, with a net profit of $-128.5M (down 15.8% YoY) (-45.7% margin). Cost of goods sold was $99.5M, operating expenses totaled $302.6M.

Key Financial Metrics

Total Revenue$281.3M
Net Profit$-128.5M
Gross Margin64.6%
Operating Margin-43.0%
Report PeriodQ4 2025

Revenue Breakdown

Guardant Health, Inc. Q4 2025 revenue of $281.3M breaks down across 4 segments, led by Oncology at $189.9M (67.5% of total).

SegmentRevenue% of Total
Oncology$189.9M67.5%
Biopharma Data$54.0M19.2%
Screening$35.1M12.5%
Licensing Other$2.2M0.8%

Guardant Health, Inc. Revenue by Segment — Quarterly Trend

Guardant Health, Inc. revenue by segment across the last 4 reported quarters, showing how each business line (such as Oncology and Biopharma Data) has evolved quarter over quarter.

SegmentQ4 2025Q3 2025Q2 2025Q1 2025
Oncology$189.9M$184.4M$158.7M$150.6M
Biopharma Data$54.0M$54.7M$56.0M$45.4M
Screening$35.1M$24.1M$14.8M$5.7M
Licensing Other$2.2M$2.0M$2.6M$1.9M

Guardant Health, Inc. Annual Revenue by Year

Guardant Health, Inc. annual revenue history includes year-by-year totals (for example, 2025 revenue was $982.0M). Click any linked year to see what changed vs the prior 10-K.

YearAnnual Revenue
2025$982.0Mvs 2024
2024$739.0Mvs 2023
2023$563.9Mvs 2022
2022$449.5M

Guardant Health, Inc. Quarterly Revenue & Net Profit History

Guardant Health, Inc. quarterly results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 2025$281.3M+39.4%$-128.5M-45.7%
Q3 2025$265.2M+38.5%$-92.7M-35.0%
Q2 2025$232.1M+30.9%$-99.9M-43.0%
Q1 2025$203.5M+20.8%$-95.2M-46.8%
Q4 2024$201.8M+30.2%$-111.0M-55.0%
Q3 2024$191.5M+33.9%$-107.8M-56.3%
Q2 2024$177.2M+29.2%$-102.6M-57.9%
Q1 2024$168.5M+30.9%$-115.0M-68.2%

損益計算書

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
売上高$168.5M$177.2M$191.5M$201.8M$203.5M$232.1M$265.2M$281.3M
前年比成長30.9%29.2%33.9%30.2%20.8%30.9%38.5%39.4%

貸借対照表

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
総資産$1.70B$1.61B$1.54B$1.49B$1.34B$1.33B$1.28B$2.01B
総負債$1.64B$1.61B$1.60B$1.63B$1.60B$1.64B$1.63B$2.11B
株主資本$68.3M$-1.6M$-60.1M$-139.6M$-250.8M$-305.5M$-354.5M$-99.3M

キャッシュフロー

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
営業CF$-30.3M$-94.0M$-51.1M$-64.5M$-62.7M$-60.3M$-35.4M$-26.4M