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Side-by-side financial comparison of Agilent Technologies (A) and Vertex Pharmaceuticals (VRTX), based on the latest 10-Q / 10-K filings. Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $1.8B, roughly 1.8× Agilent Technologies). Vertex Pharmaceuticals runs the higher net margin — 17.0% vs 37.3%, a 20.4% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 7.0%). Vertex Pharmaceuticals produced more free cash flow last quarter ($348.6M vs $175.0M). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs 6.9%).

Agilent Technologies, Inc. provides application focused solutions to the life sciences, diagnostics, and applied chemical markets worldwide. The Life Sciences and Applied Markets segment offers liquid chromatography systems and components; liquid chromatography mass spectrometry systems; gas chromatography systems and components; gas chromatography mass spectrometry systems; inductively coupled plasma mass spectrometry instruments; atomic absorption instruments; microwave plasma-atomic emissi...

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

A vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.8× larger
VRTX
$3.2B
$1.8B
A
Growing faster (revenue YoY)
VRTX
VRTX
+2.6% gap
VRTX
9.5%
7.0%
A
Higher net margin
VRTX
VRTX
20.4% more per $
VRTX
37.3%
17.0%
A
More free cash flow
VRTX
VRTX
$173.6M more FCF
VRTX
$348.6M
$175.0M
A
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
6.9%
A

Income Statement — Q1 2026 vs Q4 2025

Metric
A
A
VRTX
VRTX
Revenue
$1.8B
$3.2B
Net Profit
$305.0M
$1.2B
Gross Margin
52.6%
85.4%
Operating Margin
19.6%
37.8%
Net Margin
17.0%
37.3%
Revenue YoY
7.0%
9.5%
Net Profit YoY
-4.1%
30.5%
EPS (diluted)
$1.07
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align — see 8-quarter trend below.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history — bar widths are scaled to the larger of the two companies so you can eyeball the size gap and growth trajectory without doing math. Quarters aligned by calendar period (report date) so offset fiscal years line up.

Revenue
A
A
VRTX
VRTX
Q1 26
$1.8B
Q4 25
$1.9B
$3.2B
Q3 25
$1.7B
$3.1B
Q2 25
$1.7B
$3.0B
Q1 25
$1.7B
$2.8B
Q4 24
$1.7B
$2.9B
Q3 24
$1.6B
$2.8B
Q2 24
$1.6B
$2.6B
Net Profit
A
A
VRTX
VRTX
Q1 26
$305.0M
Q4 25
$434.0M
$1.2B
Q3 25
$336.0M
$1.1B
Q2 25
$215.0M
$1.0B
Q1 25
$318.0M
$646.3M
Q4 24
$351.0M
$913.0M
Q3 24
$282.0M
$1.0B
Q2 24
$308.0M
$-3.6B
Gross Margin
A
A
VRTX
VRTX
Q1 26
52.6%
Q4 25
53.2%
85.4%
Q3 25
51.1%
86.5%
Q2 25
51.9%
86.3%
Q1 25
53.5%
86.9%
Q4 24
53.9%
85.5%
Q3 24
54.2%
85.8%
Q2 24
54.4%
85.9%
Operating Margin
A
A
VRTX
VRTX
Q1 26
19.6%
Q4 25
23.8%
37.8%
Q3 25
20.7%
38.6%
Q2 25
18.0%
38.8%
Q1 25
22.4%
22.7%
Q4 24
24.0%
35.2%
Q3 24
21.1%
40.3%
Q2 24
23.1%
-132.9%
Net Margin
A
A
VRTX
VRTX
Q1 26
17.0%
Q4 25
23.3%
37.3%
Q3 25
19.3%
35.2%
Q2 25
12.9%
34.8%
Q1 25
18.9%
23.3%
Q4 24
20.6%
31.4%
Q3 24
17.9%
37.7%
Q2 24
19.6%
-135.8%
EPS (diluted)
A
A
VRTX
VRTX
Q1 26
$1.07
Q4 25
$1.53
$4.64
Q3 25
$1.18
$4.20
Q2 25
$0.75
$3.99
Q1 25
$1.11
$2.49
Q4 24
$1.23
$3.62
Q3 24
$0.97
$4.01
Q2 24
$1.05
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest filing — the kind of financial-strength check premium terminals charge for.

Metric
A
A
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$1.8B
$6.6B
Total DebtLower is stronger
$3.0B
Stockholders' EquityBook value
$6.9B
$18.7B
Total Assets
$12.8B
$25.6B
Debt / EquityLower = less leverage
0.44×

8-quarter trend — quarters aligned by calendar period so offset fiscal years match up.

Cash + ST Investments
A
A
VRTX
VRTX
Q1 26
$1.8B
Q4 25
$1.8B
$6.6B
Q3 25
$1.5B
$6.3B
Q2 25
$1.5B
$6.4B
Q1 25
$1.5B
$6.2B
Q4 24
$1.3B
$6.1B
Q3 24
$1.8B
$6.5B
Q2 24
$1.7B
$5.8B
Total Debt
A
A
VRTX
VRTX
Q1 26
$3.0B
Q4 25
$3.0B
Q3 25
$3.4B
Q2 25
$3.3B
Q1 25
$3.3B
Q4 24
$3.3B
Q3 24
$2.1B
Q2 24
$2.1B
Stockholders' Equity
A
A
VRTX
VRTX
Q1 26
$6.9B
Q4 25
$6.7B
$18.7B
Q3 25
$6.4B
$17.3B
Q2 25
$6.1B
$17.2B
Q1 25
$6.0B
$16.5B
Q4 24
$5.9B
$16.4B
Q3 24
$5.9B
$15.6B
Q2 24
$6.2B
$14.8B
Total Assets
A
A
VRTX
VRTX
Q1 26
$12.8B
Q4 25
$12.7B
$25.6B
Q3 25
$12.2B
$24.9B
Q2 25
$12.2B
$24.0B
Q1 25
$11.9B
$22.9B
Q4 24
$11.8B
$22.5B
Q3 24
$11.0B
$22.2B
Q2 24
$10.9B
$20.1B
Debt / Equity
A
A
VRTX
VRTX
Q1 26
0.44×
Q4 25
0.45×
Q3 25
0.53×
Q2 25
0.55×
Q1 25
0.56×
Q4 24
0.57×
Q3 24
0.36×
Q2 24
0.34×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Net income can be massaged; cash flow is harder to fake.

Metric
A
A
VRTX
VRTX
Operating Cash FlowLast quarter
$268.0M
$498.0M
Free Cash FlowOCF − Capex
$175.0M
$348.6M
FCF MarginFCF / Revenue
9.7%
10.9%
Capex IntensityCapex / Revenue; lower = less reinvestment burden
5.2%
4.7%
Cash ConversionOCF / Net Profit; >1× = earnings back up with cash
0.88×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$993.0M
$3.2B

8-quarter trend — quarters aligned by calendar period so offset fiscal years match up.

Operating Cash Flow
A
A
VRTX
VRTX
Q1 26
$268.0M
Q4 25
$545.0M
$498.0M
Q3 25
$362.0M
$1.2B
Q2 25
$221.0M
$1.1B
Q1 25
$431.0M
$818.9M
Q4 24
$481.0M
$584.6M
Q3 24
$452.0M
$1.4B
Q2 24
$333.0M
$-3.8B
Free Cash Flow
A
A
VRTX
VRTX
Q1 26
$175.0M
Q4 25
$452.0M
$348.6M
Q3 25
$259.0M
$1.1B
Q2 25
$107.0M
$927.4M
Q1 25
$334.0M
$778.2M
Q4 24
$388.0M
$492.0M
Q3 24
$360.0M
$1.3B
Q2 24
$230.0M
$-3.8B
FCF Margin
A
A
VRTX
VRTX
Q1 26
9.7%
Q4 25
24.3%
10.9%
Q3 25
14.9%
37.0%
Q2 25
6.4%
31.3%
Q1 25
19.9%
28.1%
Q4 24
22.8%
16.9%
Q3 24
22.8%
47.0%
Q2 24
14.6%
-144.5%
Capex Intensity
A
A
VRTX
VRTX
Q1 26
5.2%
Q4 25
5.0%
4.7%
Q3 25
5.9%
3.3%
Q2 25
6.8%
4.9%
Q1 25
5.8%
1.5%
Q4 24
5.5%
3.2%
Q3 24
5.8%
2.4%
Q2 24
6.5%
2.6%
Cash Conversion
A
A
VRTX
VRTX
Q1 26
0.88×
Q4 25
1.26×
0.42×
Q3 25
1.08×
1.15×
Q2 25
1.03×
1.04×
Q1 25
1.36×
1.27×
Q4 24
1.37×
0.64×
Q3 24
1.60×
1.31×
Q2 24
1.08×

Financial Flow Comparison

Sankey diagram of revenue → gross profit → operating profit → net profit for each company. Charts shown full-width and stacked so both segment hierarchies are readable side-by-side on desktop and mobile.

Revenue Breakdown by Segment

A
A

Service Other$525.0M29%
Chemicaland Energy Market$422.0M23%
Agilent Cross Lab$273.0M15%
Environmentaland Forensics Market$177.0M10%
Food Market$166.0M9%
Academiaand Government Market$130.0M7%
Applied Markets$98.0M5%

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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