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IONIS PHARMACEUTICALS INC（IONS）与OneStream, Inc.（OS）财务数据对比。点击上方公司名可切换其他公司
IONIS PHARMACEUTICALS INC的季度营收约是OneStream, Inc.的1.2倍（$203.3M vs $163.7M），OneStream, Inc.净利率更高（0.6% vs -112.8%，领先113.4%），OneStream, Inc.同比增速更快（23.6% vs -10.3%），OneStream, Inc.自由现金流更多（$25.6M vs $-159.0M），过去两年IONIS PHARMACEUTICALS INC的营收复合增速更高（30.4% vs 21.8%）
IONIS制药是1989年成立的生物科技企业，总部位于美国加利福尼亚州卡尔斯巴德，专注于反义疗法、RNA干扰及CRISPR疗法的研发，2015年12月前曾以Isis制药的名称运营。
Blue Stream面向美国佛罗里达州科勒尔斯普林斯、韦斯顿两地的居民及商业客户，提供有线电视、有线固话、数字录像服务，以及最高速率达1G的宽带互联网接入服务，深耕当地通信市场，为用户提供稳定可靠的多元通信解决方案。
IONS vs OS — 直观对比
营收规模更大
IONS
是对方的1.2倍
$163.7M
营收增速更快
OS
高出33.9%
-10.3%
净利率更高
OS
高出113.4%
-112.8%
自由现金流更多
OS
多$184.7M
$-159.0M
两年增速更快
IONS
近两年复合增速
21.8%
损益表 — Q4 FY2025 vs Q4 FY2025
| 指标 | | |
|---|---|---|
| 营收 | $203.3M | $163.7M |
| 净利润 | $-229.4M | $999.0K |
| 毛利率 | 96.1% | 69.8% |
| 营业利润率 | -105.5% | -3.2% |
| 净利率 | -112.8% | 0.6% |
| 营收同比 | -10.3% | 23.6% |
| 净利润同比 | -119.8% | — |
| 每股收益（稀释后） | $-1.35 | — |
绿色 = 该指标领先。财年不对齐时期间可能不同
8季度营收与利润趋势
并排季度历史对比，按日历期对齐，财年错位的公司也能正确匹配
营收IONSOS
| Q4 25 | $203.3M | $163.7M | ||
| Q3 25 | $156.7M | $154.3M | ||
| Q2 25 | $452.0M | $147.6M | ||
| Q1 25 | $131.6M | $136.3M | ||
| Q4 24 | $226.6M | $132.5M | ||
| Q3 24 | $133.8M | $129.1M | ||
| Q2 24 | $225.3M | $117.5M | ||
| Q1 24 | $119.5M | $110.3M |
净利润IONSOS
| Q4 25 | $-229.4M | $999.0K | ||
| Q3 25 | $-128.6M | $-8.8M | ||
| Q2 25 | $123.6M | $-18.4M | ||
| Q1 25 | $-146.9M | $-24.0M | ||
| Q4 24 | $-104.3M | — | ||
| Q3 24 | $-140.5M | $-171.9M | ||
| Q2 24 | $-66.3M | $-7.8M | ||
| Q1 24 | $-142.8M | $-5.0M |
毛利率IONSOS
| Q4 25 | 96.1% | 69.8% | ||
| Q3 25 | 98.5% | 68.1% | ||
| Q2 25 | 99.1% | 68.6% | ||
| Q1 25 | 98.9% | 68.0% | ||
| Q4 24 | 98.3% | 66.8% | ||
| Q3 24 | 99.2% | 50.1% | ||
| Q2 24 | 98.2% | 68.5% | ||
| Q1 24 | 98.2% | 69.1% |
营业利润率IONSOS
| Q4 25 | -105.5% | -3.2% | ||
| Q3 25 | -102.2% | -11.3% | ||
| Q2 25 | 30.9% | -21.8% | ||
| Q1 25 | -111.6% | -29.3% | ||
| Q4 24 | -48.9% | -35.8% | ||
| Q3 24 | -111.1% | -197.6% | ||
| Q2 24 | -29.3% | -9.8% | ||
| Q1 24 | -125.1% | -4.9% |
净利率IONSOS
| Q4 25 | -112.8% | 0.6% | ||
| Q3 25 | -82.1% | -5.7% | ||
| Q2 25 | 27.3% | -12.5% | ||
| Q1 25 | -111.6% | -17.6% | ||
| Q4 24 | -46.1% | — | ||
| Q3 24 | -105.0% | -133.1% | ||
| Q2 24 | -29.4% | -6.7% | ||
| Q1 24 | -119.5% | -4.5% |
每股收益（稀释后）IONSOS
| Q4 25 | $-1.35 | — | ||
| Q3 25 | $-0.80 | — | ||
| Q2 25 | $0.70 | — | ||
| Q1 25 | $-0.93 | — | ||
| Q4 24 | $-0.66 | — | ||
| Q3 24 | $-0.95 | $-1.06 | ||
| Q2 24 | $-0.45 | — | ||
| Q1 24 | $-0.98 | — |
资产负债表与财务实力
最新季度各公司的流动性、杠杆与账面价值一览
| 指标 | | |
|---|---|---|
| 现金及短期投资手头流动性 | $2.7B | $693.6M |
| 总债务越低越好 | $1.8B | — |
| 股东权益账面价值 | $489.1M | $504.7M |
| 总资产 | $3.5B | $1.0B |
| 负债/权益比越低杠杆越低 | 3.71× | — |
8季度趋势，按日历期对齐
现金及短期投资IONSOS
| Q4 25 | $2.7B | $693.6M | ||
| Q3 25 | $2.2B | $653.9M | ||
| Q2 25 | $2.3B | $652.1M | ||
| Q1 25 | $2.1B | $593.9M | ||
| Q4 24 | $2.3B | $544.2M | ||
| Q3 24 | $2.5B | $495.5M | ||
| Q2 24 | $2.1B | $140.5M | ||
| Q1 24 | $2.2B | — |
总债务IONSOS
| Q4 25 | $1.8B | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | $1.3B | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
股东权益IONSOS
| Q4 25 | $489.1M | $504.7M | ||
| Q3 25 | $618.0M | $472.1M | ||
| Q2 25 | $631.7M | $458.2M | ||
| Q1 25 | $475.7M | $412.9M | ||
| Q4 24 | $588.4M | $386.2M | ||
| Q3 24 | $662.5M | $458.2M | ||
| Q2 24 | $263.7M | $97.5M | ||
| Q1 24 | $296.5M | $102.5M |
总资产IONSOS
| Q4 25 | $3.5B | $1.0B | ||
| Q3 25 | $3.0B | $949.4M | ||
| Q2 25 | $3.0B | $910.5M | ||
| Q1 25 | $2.8B | $867.3M | ||
| Q4 24 | $3.0B | $823.2M | ||
| Q3 24 | $3.1B | $750.1M | ||
| Q2 24 | $2.7B | $379.7M | ||
| Q1 24 | $2.8B | — |
负债/权益比IONSOS
| Q4 25 | 3.71× | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | 2.13× | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
现金流与资本效率
扣除再投资后实际产生的现金。现金流比净利润更难造假
| 指标 | | |
|---|---|---|
| 经营现金流最新季度 | $-137.7M | $25.8M |
| 自由现金流经营现金流 - 资本支出 | $-159.0M | $25.6M |
| 自由现金流率自由现金流/营收 | -78.2% | 15.7% |
| 资本支出强度资本支出/营收 | 10.5% | 0.1% |
| 现金转化率经营现金流/净利润 | — | 25.79× |
| 过去12个月自由现金流最近4个季度 | $-320.0M | $95.6M |
8季度趋势，按日历期对齐
经营现金流IONSOS
| Q4 25 | $-137.7M | $25.8M | ||
| Q3 25 | $-131.4M | $5.0M | ||
| Q2 25 | $151.3M | $29.7M | ||
| Q1 25 | $-150.8M | $36.2M | ||
| Q4 24 | $-116.1M | — | ||
| Q3 24 | $-115.0M | $2.4M | ||
| Q2 24 | $-119.9M | $8.1M | ||
| Q1 24 | $-149.9M | $25.5M |
自由现金流IONSOS
| Q4 25 | $-159.0M | $25.6M | ||
| Q3 25 | $-136.7M | $4.8M | ||
| Q2 25 | $139.0M | $29.4M | ||
| Q1 25 | $-163.4M | $35.8M | ||
| Q4 24 | $-141.6M | — | ||
| Q3 24 | $-124.0M | $1.3M | ||
| Q2 24 | $-126.1M | $7.7M | ||
| Q1 24 | $-154.4M | $24.9M |
自由现金流率IONSOS
| Q4 25 | -78.2% | 15.7% | ||
| Q3 25 | -87.2% | 3.1% | ||
| Q2 25 | 30.8% | 19.9% | ||
| Q1 25 | -124.1% | 26.3% | ||
| Q4 24 | -62.5% | — | ||
| Q3 24 | -92.7% | 1.0% | ||
| Q2 24 | -56.0% | 6.6% | ||
| Q1 24 | -129.2% | 22.5% |
资本支出强度IONSOS
| Q4 25 | 10.5% | 0.1% | ||
| Q3 25 | 3.4% | 0.1% | ||
| Q2 25 | 2.7% | 0.2% | ||
| Q1 25 | 9.6% | 0.3% | ||
| Q4 24 | 11.3% | — | ||
| Q3 24 | 6.8% | 0.8% | ||
| Q2 24 | 2.8% | 0.3% | ||
| Q1 24 | 3.8% | 0.6% |
现金转化率IONSOS
| Q4 25 | — | 25.79× | ||
| Q3 25 | — | — | ||
| Q2 25 | 1.22× | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
财务流量对比
营收 → 毛利润 → 营业利润 → 净利润流向图
业务分部营收拆解
IONS
| Products | $58.0M | 29% |
| Spinraza Royalties | $54.0M | 27% |
| Collaborative Agreement Revenue | $52.4M | 26% |
| Wainus Royalties | $16.0M | 8% |
| Wainua Joint Development Revenue | $9.6M | 5% |
| Other Commercial | $7.6M | 4% |
| Other Royalties | $5.7M | 3% |
OS
| Subscription And Circulation | $150.3M | 92% |
| Professional Services And Other | $9.4M | 6% |
| License | $4.0M | 2% |
