AGIOS PHARMACEUTICALS, INC.AGIOEarnings & Financial Report
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
AGIO Q4 2025 Key Financial Metrics
Revenue
$20.0M
Gross Profit
$18.1M
Operating Profit
$-121.6M
Net Profit
$-108.0M
Gross Margin
90.6%
Operating Margin
-608.9%
Net Margin
-541.1%
YoY Growth
86.1%
EPS
$-1.86
Financial Flow
AGIOS PHARMACEUTICALS, INC. Q4 2025 Financial Summary
AGIOS PHARMACEUTICALS, INC. reported revenue of $20.0M for Q4 2025, with a net profit of $-108.0M (-541.1% margin). Cost of goods sold was $1.9M, operating expenses totaled $139.7M.
Key Financial Metrics
| Total Revenue | $20.0M |
|---|---|
| Net Profit | $-108.0M |
| Gross Margin | 90.6% |
| Operating Margin | -608.9% |
| Report Period | Q4 2025 |
AGIOS PHARMACEUTICALS, INC. Annual Revenue by Year
AGIOS PHARMACEUTICALS, INC. annual revenue history includes year-by-year totals (for example, 2025 revenue was $54.0M).
| Year | Annual Revenue |
|---|---|
| 2025 | $54.0M |
| 2024 | $36.5M |
| 2023 | $26.8M |
| 2022 | $14.2M |
Income Statement
| Q1 2024 | Q2 2024 | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | |
|---|---|---|---|---|---|---|---|---|
| Revenue | $8.2M | $8.6M | $9.0M | $10.7M | $8.7M | $12.5M | $12.9M | $20.0M |
| YoY Growth | 46.0% | 28.4% | 21.2% | 51.1% | 6.6% | 44.6% | 43.7% | 86.1% |
Balance Sheet
| Q1 2024 | Q2 2024 | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | |
|---|---|---|---|---|---|---|---|---|
| Assets | $849.7M | $773.1M | $1.79B | $1.66B | $1.56B | $1.47B | $1.39B | $1.30B |
| Liabilities | $105.8M | $112.6M | $165.1M | $122.2M | $89.0M | $101.7M | $101.4M | $104.1M |
| Equity | $743.9M | $660.5M | $1.63B | $1.54B | $1.47B | $1.37B | $1.28B | $1.19B |
Cash Flow
| Q1 2024 | Q2 2024 | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | |
|---|---|---|---|---|---|---|---|---|
| Operating CF | $-99.9M | $-72.6M | $-84.2M | $-133.2M | $-111.5M | $-77.1M | $-88.2M | $-96.2M |
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