Protalix BioTherapeutics, Inc.

Protalix BioTherapeutics, Inc.PLXEarnings & Financial Report

NYSE · Health Care · Biological Products, (No Diagnostic Substances)

Protalix BioTherapeutics is an Israeli pharmaceutical company that manufactures a plant-based enzyme, taliglucerase alfa, which has received U.S. Food and Drug Administration approval for the treatment of Gaucher disease.

PLX Q4 FY2025 Key Financial Metrics

Revenue

$9.1M

Gross Profit

$4.5M

Operating Profit

$-4.7M

Net Profit

$-5.5M

Gross Margin

49.4%

Operating Margin

-51.1%

Net Margin

-60.3%

YoY Growth

-49.9%

EPS

$-0.06

Protalix BioTherapeutics, Inc. Q4 FY2025 Financial Summary

Protalix BioTherapeutics, Inc. reported revenue of $9.1M (down 49.9% YoY) for Q4 FY2025, with a net profit of $-5.5M (down 184.8% YoY) (-60.3% margin). Cost of goods sold was $4.6M, operating expenses totaled $9.2M.

Key Financial Metrics

Total Revenue$9.1M
Net Profit$-5.5M
Gross Margin49.4%
Operating Margin-51.1%
Report PeriodQ4 FY2025

Revenue Breakdown

Protalix BioTherapeutics, Inc. Q4 FY2025 revenue of $9.1M breaks down across 2 segments, led by Products at $8.7M (95.3% of total).

SegmentRevenue% of Total
Products$8.7M95.3%
Other$428.0K4.7%

Protalix BioTherapeutics, Inc. Revenue by Segment — Quarterly Trend

Protalix BioTherapeutics, Inc. revenue by segment across the last 4 reported quarters, showing how each business line (such as Products and Other) has evolved quarter over quarter.

SegmentQ4 FY2025Q3 FY2025Q2 FY2025Q1 FY2025
Products$8.7M$10.0M
Other$428.0K

Protalix BioTherapeutics, Inc. Annual Revenue by Year

Protalix BioTherapeutics, Inc. annual revenue history includes year-by-year totals (for example, 2025 revenue was $52.7M).

YearAnnual Revenue
2025$52.7Mvs 2024
2023$65.5Mvs 2022
2022$47.6M

Protalix BioTherapeutics, Inc. Quarterly Revenue & Net Profit History

Protalix BioTherapeutics, Inc. results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 FY2025$9.1M-49.9%$-5.5M-60.3%
Q3 FY2025$17.9M-0.6%$2.4M13.2%
Q2 FY2025$15.7M+16.2%$164.0K1.0%
Q1 FY2025$10.1M+169.8%$-3.6M-35.8%
Q4 FY2024$18.2M+73.7%$6.5M35.6%
Q3 FY2024$18.0M+73.6%$3.2M18.0%
Q2 FY2024$13.5M-61.6%$-2.2M-16.4%
Q4 FY2023$10.5M+21.7%$-6.0M-57.6%

Income Statement

Q4 2023Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Revenue$10.5M$13.5M$18.0M$18.2M$10.1M$15.7M$17.9M$9.1M
YoY Growth21.7%-61.6%73.6%73.7%169.8%16.2%-0.6%-49.9%

Balance Sheet

Q4 2023Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Assets$84.4M$91.5M$61.6M$73.4M$73.9M$78.5M$82.3M$82.3M
Liabilities$50.9M$63.0M$29.1M$30.2M$28.7M$28.6M$29.4M$34.1M
Equity$33.6M$28.6M$32.4M$43.2M$45.2M$49.9M$52.9M$48.2M

Cash Flow

Q4 2023Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$3.6M$-3.6M$4.1M$4.0M$-5.1M$-5.2M$-3.7M$2.0M