Prime Medicine, Inc.

Prime Medicine, Inc.PRMEEarnings & Financial Report

Nasdaq · Health Care · Biological Products, (No Diagnostic Substances)

Prime Medicine, Inc. is an American biotechnology company developing gene therapies based on prime editing. The company is headquartered in Cambridge, Massachusetts.

PRME Q4 FY2025 Key Financial Metrics

Revenue

$838.0K

Gross Profit

N/A

Operating Profit

$-48.6M

Net Profit

$-46.1M

Gross Margin

N/A

Operating Margin

-5800.5%

Net Margin

-5498.7%

YoY Growth

-61.6%

EPS

$-0.22

Prime Medicine, Inc. Q4 FY2025 Financial Summary

Prime Medicine, Inc. reported revenue of $838.0K (down 61.6% YoY) for Q4 FY2025, with a net profit of $-46.1M (down 9.0% YoY) (-5498.7% margin).

Key Financial Metrics

Total Revenue$838.0K
Net Profit$-46.1M
Gross MarginN/A
Operating Margin-5800.5%
Report PeriodQ4 FY2025

Prime Medicine, Inc. Annual Revenue by Year

Prime Medicine, Inc. annual revenue history includes year-by-year totals (for example, 2025 revenue was $4.6M).

YearAnnual Revenue
2025$4.6Mvs 2024
2023$0vs 2022

Prime Medicine, Inc. Quarterly Revenue & Net Profit History

Prime Medicine, Inc. results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 FY2025$838.0K-61.6%$-46.1M-5498.7%
Q3 FY2025$1.2M+486.1%$-50.6M-4129.1%
Q2 FY2025$1.1M$-52.6M-4716.7%
Q1 FY2025$1.5M+146.0%$-51.9M-3568.8%
Q4 FY2024$2.2M$-42.3M-1936.6%
Q2 FY2024$0$-55.3MN/A
Q1 FY2024$591.0K$-45.8M-7743.0%
Q4 FY2023$0$-65.6MN/A

Income Statement

Q4 2023Q1 2024Q2 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Revenue$0$591000$0$2.2M$1.5M$1.1M$1.2M$838000
YoY GrowthN/AN/AN/AN/A146.0%N/A486.1%-61.6%

Balance Sheet

Q4 2023Q1 2024Q2 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Assets$193.9M$311.4M$259.7M$297.5M$328.2M$279.0M$385.0M$342.7M
Liabilities$60.8M$67.6M$63.1M$144.4M$221.2M$218.1M$223.2M$221.9M
Equity$133.1M$243.8M$196.6M$153.1M$106.9M$60.9M$161.8M$120.9M

Cash Flow

Q4 2023Q1 2024Q2 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$-43.9M$-67.7M$-45.5M$16.2M$-48.9M$-41.4M$-35.0M$-37.3M