REGENXBIO Inc.

REGENXBIO Inc.RGNXEarnings & Financial Report

Nasdaq · Health Care · Biological Products, (No Diagnostic Substances)

REGENXBIO Inc. is a clinical-stage biotechnology firm focused on gene therapy for rare severe genetic diseases. It licenses its proprietary AAV vector technology to global biopharma partners, and advances its own pipeline targeting ophthalmology, metabolic and neurodegenerative disorders.

RGNX Q4 FY2025 Key Financial Metrics

Revenue

$30.3M

Gross Profit

N/A

Operating Profit

$-57.6M

Net Profit

$-67.1M

Gross Margin

N/A

Operating Margin

-190.0%

Net Margin

-221.3%

YoY Growth

43.0%

EPS

$-1.30

REGENXBIO Inc. Q4 FY2025 Financial Summary

REGENXBIO Inc. reported revenue of $30.3M (up 43.0% YoY) for Q4 FY2025, with a net profit of $-67.1M (down 31.2% YoY) (-221.3% margin).

Key Financial Metrics

Total Revenue$30.3M
Net Profit$-67.1M
Gross MarginN/A
Operating Margin-190.0%
Report PeriodQ4 FY2025

Revenue Breakdown

REGENXBIO Inc. Q4 FY2025 revenue of $30.3M breaks down across 3 segments, led by Novartis Gene Therapies at $24.2M (79.7% of total).

SegmentRevenue% of Total
Novartis Gene Therapies$24.2M79.7%
Nippon Shinyaku Collaboration And License Agreement$4.3M14.2%
Nippon Shinyaku Services$1.4M4.6%

REGENXBIO Inc. Revenue by Segment — Quarterly Trend

REGENXBIO Inc. revenue by segment across the last 4 reported quarters, showing how each business line (such as Novartis Gene Therapies and Nippon Shinyaku Collaboration And License Agreement) has evolved quarter over quarter.

SegmentQ4 FY2025Q3 FY2025Q2 FY2025Q1 FY2025
Novartis Gene Therapies$24.2M$23.6M$18.4M$17.0M
Nippon Shinyaku Collaboration And License Agreement$4.3M$5.9M$2.7M
Nippon Shinyaku Services$1.4M

REGENXBIO Inc. Annual Revenue by Year

REGENXBIO Inc. annual revenue history includes year-by-year totals (for example, 2025 revenue was $170.4M).

YearAnnual Revenue
2025$170.4Mvs 2024
2024$83.3Mvs 2023
2023$90.2Mvs 2022
2022$112.7M

REGENXBIO Inc. Quarterly Revenue & Net Profit History

REGENXBIO Inc. results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 FY2025$30.3M+43.0%$-67.1M-221.3%
Q3 FY2025$29.7M+22.9%$-61.9M-208.3%
Q2 FY2025$21.4M-4.2%$-70.9M-331.8%
Q1 FY2025$89.0M+469.8%$6.1M6.8%
Q4 FY2024$21.2M-4.5%$-51.2M-241.3%
Q3 FY2024$24.2M-16.3%$-59.6M-246.3%
Q2 FY2024$22.3M+11.6%$-53.0M-237.7%
Q1 FY2024$15.6M-18.4%$-63.3M-405.4%

Income Statement

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Revenue$15.6M$22.3M$24.2M$21.2M$89.0M$21.4M$29.7M$30.3M
YoY Growth-18.4%11.6%-16.3%-4.5%469.8%-4.2%22.9%43.0%

Balance Sheet

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Assets$629.2M$569.4M$519.1M$466.0M$490.9M$581.0M$525.2M$453.0M
Liabilities$238.5M$221.1M$217.7M$206.3M$216.7M$367.3M$363.8M$350.3M
Equity$390.7M$348.3M$301.4M$259.7M$274.2M$213.7M$161.5M$102.7M

Cash Flow

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$-55.5M$-45.5M$-40.5M$-31.6M$33.6M$-49.3M$-56.0M$-52.3M