Sarepta Therapeutics, Inc.

Sarepta Therapeutics, Inc.SRPTEarnings & Financial Report

Nasdaq · Health Care · Pharmaceutical Preparations

Sarepta Therapeutics, Inc. is a medical research and drug development company with corporate offices and research facilities in Cambridge, Massachusetts, United States. Incorporated in 1980 as AntiVirals, shortly before going public the company changed its name from AntiVirals to AVI BioPharma soon with stock symbol AVII and in July 2012 changed name from AVI BioPharma to Sarepta Therapeutics and SRPT respectively. As of 2023, the company has four approved drugs.

SRPT Q4 FY2025 Key Financial Metrics

Revenue

$369.6M

Gross Profit

N/A

Operating Profit

$-411.6M

Net Profit

$-412.2M

Gross Margin

N/A

Operating Margin

-111.4%

Net Margin

-111.5%

YoY Growth

-42.1%

EPS

$-3.92

Sarepta Therapeutics, Inc. Q4 FY2025 Financial Summary

Sarepta Therapeutics, Inc. reported revenue of $369.6M (down 42.1% YoY) for Q4 FY2025, with a net profit of $-412.2M (down 359.2% YoY) (-111.5% margin).

Key Financial Metrics

Total Revenue$369.6M
Net Profit$-412.2M
Gross MarginN/A
Operating Margin-111.4%
Report PeriodQ4 FY2025

Revenue Breakdown

Sarepta Therapeutics, Inc. Q4 FY2025 revenue of $369.6M breaks down across 3 segments, led by Pmo Products at $202.5M (54.8% of total).

SegmentRevenue% of Total
Pmo Products$202.5M54.8%
Elevidys$110.4M29.9%
Other$56.7M15.3%

Sarepta Therapeutics, Inc. Revenue by Segment — Quarterly Trend

Sarepta Therapeutics, Inc. revenue by segment across the last 4 reported quarters, showing how each business line (such as Pmo Products and Elevidys) has evolved quarter over quarter.

SegmentQ4 FY2025Q3 FY2025Q2 FY2025Q1 FY2025
Pmo Products$202.5M$209.1M$202.9M$185.8M
Elevidys$110.4M$131.5M$281.9M$375.0M
Other$56.7M$29.4M$28.4M$50.7M

Sarepta Therapeutics, Inc. Annual Revenue by Year

Sarepta Therapeutics, Inc. annual revenue history includes year-by-year totals (for example, 2025 revenue was $1.9B).

YearAnnual Revenue
2025$1.9Bvs 2024
2024$1.8Bvs 2023
2023$1.1Bvs 2022
2022$843.8M

Sarepta Therapeutics, Inc. Quarterly Revenue & Net Profit History

Sarepta Therapeutics, Inc. results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 FY2025$369.6M-42.1%$-412.2M-111.5%
Q3 FY2025$370.0M-13.9%$-50.6M-13.7%
Q2 FY2025$513.1M+42.3%$196.9M38.4%
Q1 FY2025$611.5M+70.1%$-447.5M-73.2%
Q4 FY2024$638.2M+74.8%$159.0M24.9%
Q3 FY2024$429.8M+38.9%$33.6M7.8%
Q2 FY2024$360.5M+50.9%$6.5M1.8%
Q1 FY2024$359.5M+55.3%$36.1M10.0%

Income Statement

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Revenue$359.5M$360.5M$429.8M$638.2M$611.5M$513.1M$370.0M$369.6M
YoY Growth55.3%50.9%38.9%74.8%70.1%42.3%-13.9%-42.1%

Balance Sheet

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Assets$3.22B$3.42B$3.60B$3.96B$3.47B$3.68B$3.49B$3.35B
Liabilities$2.26B$2.35B$2.38B$2.44B$2.32B$2.32B$2.17B$2.21B
Equity$961.2M$1.08B$1.22B$1.53B$1.14B$1.36B$1.32B$1.14B

Cash Flow

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$-242.1M$14.9M$-70.7M$92.0M$-583.4M$261.3M$-14.6M$131.2M