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Side-by-side financial comparison of ACADIA PHARMACEUTICALS INC (ACAD) and SPS COMMERCE INC (SPSC). Click either name above to swap in a different company.
ACADIA PHARMACEUTICALS INC is the larger business by last-quarter revenue ($284.0M vs $192.7M, roughly 1.5× SPS COMMERCE INC). ACADIA PHARMACEUTICALS INC runs the higher net margin — 96.3% vs 13.4%, a 82.9% gap on every dollar of revenue. On growth, SPS COMMERCE INC posted the faster year-over-year revenue change (12.7% vs 9.4%). Over the past eight quarters, ACADIA PHARMACEUTICALS INC's revenue compounded faster (17.5% CAGR vs 13.5%).
Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, San Diego, California.
SPS Commerce, Inc. is a technology and application software company based in the United States that provides cloud-based supply chain management software. The company's headquarters are located in Minneapolis, Minnesota, but it also has a US office in New Jersey, and international locations in Amsterdam, Beijing, Breukelen, Hong Kong, Kyiv, Melbourne, Montpellier, Sydney, and Toronto.
ACAD vs SPSC — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $284.0M | $192.7M |
| Net Profit | $273.6M | $25.8M |
| Gross Margin | 90.8% | 70.4% |
| Operating Margin | 6.1% | 18.0% |
| Net Margin | 96.3% | 13.4% |
| Revenue YoY | 9.4% | 12.7% |
| Net Profit YoY | 90.3% | 47.2% |
| EPS (diluted) | $1.61 | $0.69 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $284.0M | $192.7M | ||
| Q3 25 | $278.6M | $189.9M | ||
| Q2 25 | $264.6M | $187.4M | ||
| Q1 25 | $244.3M | $181.5M | ||
| Q4 24 | $259.6M | $170.9M | ||
| Q3 24 | $250.4M | $163.7M | ||
| Q2 24 | $242.0M | $153.6M | ||
| Q1 24 | $205.8M | $149.6M |
| Q4 25 | $273.6M | $25.8M | ||
| Q3 25 | $71.8M | $25.6M | ||
| Q2 25 | $26.7M | $19.7M | ||
| Q1 25 | $19.0M | $22.2M | ||
| Q4 24 | $143.7M | $17.6M | ||
| Q3 24 | $32.8M | $23.5M | ||
| Q2 24 | $33.4M | $18.0M | ||
| Q1 24 | $16.6M | $18.0M |
| Q4 25 | 90.8% | 70.4% | ||
| Q3 25 | 92.2% | 69.5% | ||
| Q2 25 | 92.2% | 68.1% | ||
| Q1 25 | 91.7% | 68.7% | ||
| Q4 24 | 91.6% | 67.5% | ||
| Q3 24 | 92.5% | 68.5% | ||
| Q2 24 | 92.5% | 66.1% | ||
| Q1 24 | 88.8% | 65.6% |
| Q4 25 | 6.1% | 18.0% | ||
| Q3 25 | 12.8% | 16.4% | ||
| Q2 25 | 12.2% | 14.1% | ||
| Q1 25 | 7.9% | 14.3% | ||
| Q4 24 | 59.1% | 14.5% | ||
| Q3 24 | 12.6% | 15.6% | ||
| Q2 24 | 12.6% | 15.1% | ||
| Q1 24 | 7.4% | 10.3% |
| Q4 25 | 96.3% | 13.4% | ||
| Q3 25 | 25.8% | 13.5% | ||
| Q2 25 | 10.1% | 10.5% | ||
| Q1 25 | 7.8% | 12.2% | ||
| Q4 24 | 55.4% | 10.3% | ||
| Q3 24 | 13.1% | 14.3% | ||
| Q2 24 | 13.8% | 11.7% | ||
| Q1 24 | 8.0% | 12.0% |
| Q4 25 | $1.61 | $0.69 | ||
| Q3 25 | $0.42 | $0.67 | ||
| Q2 25 | $0.16 | $0.52 | ||
| Q1 25 | $0.11 | $0.58 | ||
| Q4 24 | $0.86 | $0.46 | ||
| Q3 24 | $0.20 | $0.62 | ||
| Q2 24 | $0.20 | $0.48 | ||
| Q1 24 | $0.10 | $0.48 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $177.7M | $151.4M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.2B | $973.9M |
| Total Assets | $1.6B | $1.2B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $177.7M | $151.4M | ||
| Q3 25 | $258.0M | $133.7M | ||
| Q2 25 | $253.6M | $107.6M | ||
| Q1 25 | $217.7M | $94.9M | ||
| Q4 24 | $319.6M | $241.0M | ||
| Q3 24 | $155.1M | $205.8M | ||
| Q2 24 | $177.1M | $271.8M | ||
| Q1 24 | $204.7M | $290.8M |
| Q4 25 | $1.2B | $973.9M | ||
| Q3 25 | $917.3M | $958.9M | ||
| Q2 25 | $822.4M | $949.8M | ||
| Q1 25 | $765.2M | $920.9M | ||
| Q4 24 | $732.8M | $854.7M | ||
| Q3 24 | $577.2M | $829.4M | ||
| Q2 24 | $516.7M | $703.4M | ||
| Q1 24 | $464.0M | $683.0M |
| Q4 25 | $1.6B | $1.2B | ||
| Q3 25 | $1.3B | $1.2B | ||
| Q2 25 | $1.2B | $1.1B | ||
| Q1 25 | $1.1B | $1.1B | ||
| Q4 24 | $1.2B | $1.0B | ||
| Q3 24 | $976.9M | $1.0B | ||
| Q2 24 | $914.1M | $854.5M | ||
| Q1 24 | $855.1M | $839.8M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-48.7M | $45.9M |
| Free Cash FlowOCF − Capex | — | $38.2M |
| FCF MarginFCF / Revenue | — | 19.8% |
| Capex IntensityCapex / Revenue | — | 4.0% |
| Cash ConversionOCF / Net Profit | -0.18× | 1.78× |
| TTM Free Cash FlowTrailing 4 quarters | — | $152.3M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-48.7M | $45.9M | ||
| Q3 25 | $74.3M | $60.6M | ||
| Q2 25 | $64.0M | $32.3M | ||
| Q1 25 | $20.3M | $40.0M | ||
| Q4 24 | $40.4M | $40.6M | ||
| Q3 24 | $63.2M | $53.3M | ||
| Q2 24 | $25.0M | $29.4M | ||
| Q1 24 | $29.1M | $34.1M |
| Q4 25 | — | $38.2M | ||
| Q3 25 | $73.9M | $54.6M | ||
| Q2 25 | — | $25.7M | ||
| Q1 25 | — | $33.8M | ||
| Q4 24 | — | $34.3M | ||
| Q3 24 | $63.2M | $48.1M | ||
| Q2 24 | — | $24.4M | ||
| Q1 24 | — | $30.5M |
| Q4 25 | — | 19.8% | ||
| Q3 25 | 26.5% | 28.7% | ||
| Q2 25 | — | 13.7% | ||
| Q1 25 | — | 18.6% | ||
| Q4 24 | — | 20.1% | ||
| Q3 24 | 25.2% | 29.4% | ||
| Q2 24 | — | 15.9% | ||
| Q1 24 | — | 20.4% |
| Q4 25 | — | 4.0% | ||
| Q3 25 | 0.1% | 3.2% | ||
| Q2 25 | — | 3.6% | ||
| Q1 25 | — | 3.4% | ||
| Q4 24 | — | 3.6% | ||
| Q3 24 | 0.0% | 3.2% | ||
| Q2 24 | — | 3.3% | ||
| Q1 24 | — | 2.4% |
| Q4 25 | -0.18× | 1.78× | ||
| Q3 25 | 1.03× | 2.37× | ||
| Q2 25 | 2.40× | 1.64× | ||
| Q1 25 | 1.07× | 1.80× | ||
| Q4 24 | 0.28× | 2.31× | ||
| Q3 24 | 1.93× | 2.27× | ||
| Q2 24 | 0.75× | 1.63× | ||
| Q1 24 | 1.76× | 1.89× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ACAD
| Nuplazid | $174.4M | 61% |
| Daybue | $109.6M | 39% |
SPSC
| Recurring Revenues | $184.5M | 96% |
| One Time Revenues | $8.1M | 4% |
| Set Up Fees | $4.1M | 2% |
