vs
Side-by-side financial comparison of ACADIA PHARMACEUTICALS INC (ACAD) and UNITED THERAPEUTICS Corp (UTHR). Click either name above to swap in a different company.
UNITED THERAPEUTICS Corp is the larger business by last-quarter revenue ($790.2M vs $284.0M, roughly 2.8× ACADIA PHARMACEUTICALS INC). ACADIA PHARMACEUTICALS INC runs the higher net margin — 96.3% vs 46.1%, a 50.2% gap on every dollar of revenue. On growth, ACADIA PHARMACEUTICALS INC posted the faster year-over-year revenue change (9.4% vs 7.4%). Over the past eight quarters, ACADIA PHARMACEUTICALS INC's revenue compounded faster (17.5% CAGR vs 8.0%).
Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, San Diego, California.
United Therapeutics Corporation is an American biotechnology company that develops pharmaceuticals and technologies related to organ transplantation, including xenotransplantation. Many of the company's products are focused towards lung disease and organ manufacturing. United Therapeutics is co-headquartered in Silver Spring, Maryland and Research Triangle Park, North Carolina, with additional facilities in Magog and Bromont, Quebec; Melbourne and Jacksonville, Florida; Blacksburg, Virginia; ...
ACAD vs UTHR — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $284.0M | $790.2M |
| Net Profit | $273.6M | $364.3M |
| Gross Margin | 90.8% | 86.9% |
| Operating Margin | 6.1% | 45.1% |
| Net Margin | 96.3% | 46.1% |
| Revenue YoY | 9.4% | 7.4% |
| Net Profit YoY | 90.3% | 20.9% |
| EPS (diluted) | $1.61 | $7.66 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $284.0M | $790.2M | ||
| Q3 25 | $278.6M | $799.5M | ||
| Q2 25 | $264.6M | $798.6M | ||
| Q1 25 | $244.3M | $794.4M | ||
| Q4 24 | $259.6M | $735.9M | ||
| Q3 24 | $250.4M | $748.9M | ||
| Q2 24 | $242.0M | $714.9M | ||
| Q1 24 | $205.8M | $677.7M |
| Q4 25 | $273.6M | $364.3M | ||
| Q3 25 | $71.8M | $338.7M | ||
| Q2 25 | $26.7M | $309.5M | ||
| Q1 25 | $19.0M | $322.2M | ||
| Q4 24 | $143.7M | $301.3M | ||
| Q3 24 | $32.8M | $309.1M | ||
| Q2 24 | $33.4M | $278.1M | ||
| Q1 24 | $16.6M | $306.6M |
| Q4 25 | 90.8% | 86.9% | ||
| Q3 25 | 92.2% | 87.4% | ||
| Q2 25 | 92.2% | 89.0% | ||
| Q1 25 | 91.7% | 88.4% | ||
| Q4 24 | 91.6% | 89.7% | ||
| Q3 24 | 92.5% | 88.9% | ||
| Q2 24 | 92.5% | 89.1% | ||
| Q1 24 | 88.8% | 89.2% |
| Q4 25 | 6.1% | 45.1% | ||
| Q3 25 | 12.8% | 48.6% | ||
| Q2 25 | 12.2% | 45.6% | ||
| Q1 25 | 7.9% | 48.2% | ||
| Q4 24 | 59.1% | 48.6% | ||
| Q3 24 | 12.6% | 45.8% | ||
| Q2 24 | 12.6% | 44.7% | ||
| Q1 24 | 7.4% | 52.6% |
| Q4 25 | 96.3% | 46.1% | ||
| Q3 25 | 25.8% | 42.4% | ||
| Q2 25 | 10.1% | 38.8% | ||
| Q1 25 | 7.8% | 40.6% | ||
| Q4 24 | 55.4% | 40.9% | ||
| Q3 24 | 13.1% | 41.3% | ||
| Q2 24 | 13.8% | 38.9% | ||
| Q1 24 | 8.0% | 45.2% |
| Q4 25 | $1.61 | $7.66 | ||
| Q3 25 | $0.42 | $7.16 | ||
| Q2 25 | $0.16 | $6.41 | ||
| Q1 25 | $0.11 | $6.63 | ||
| Q4 24 | $0.86 | $6.23 | ||
| Q3 24 | $0.20 | $6.39 | ||
| Q2 24 | $0.20 | $5.85 | ||
| Q1 24 | $0.10 | $6.17 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $177.7M | $2.9B |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.2B | $7.1B |
| Total Assets | $1.6B | $7.9B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $177.7M | $2.9B | ||
| Q3 25 | $258.0M | $2.8B | ||
| Q2 25 | $253.6M | $3.0B | ||
| Q1 25 | $217.7M | $3.3B | ||
| Q4 24 | $319.6M | $3.3B | ||
| Q3 24 | $155.1M | $3.3B | ||
| Q2 24 | $177.1M | $3.0B | ||
| Q1 24 | $204.7M | $2.7B |
| Q4 25 | $1.2B | $7.1B | ||
| Q3 25 | $917.3M | $6.6B | ||
| Q2 25 | $822.4M | $7.2B | ||
| Q1 25 | $765.2M | $6.8B | ||
| Q4 24 | $732.8M | $6.4B | ||
| Q3 24 | $577.2M | $6.1B | ||
| Q2 24 | $516.7M | $5.7B | ||
| Q1 24 | $464.0M | $5.3B |
| Q4 25 | $1.6B | $7.9B | ||
| Q3 25 | $1.3B | $7.4B | ||
| Q2 25 | $1.2B | $7.9B | ||
| Q1 25 | $1.1B | $7.7B | ||
| Q4 24 | $1.2B | $7.4B | ||
| Q3 24 | $976.9M | $7.1B | ||
| Q2 24 | $914.1M | $6.7B | ||
| Q1 24 | $855.1M | $6.5B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-48.7M | $346.2M |
| Free Cash FlowOCF − Capex | — | $173.3M |
| FCF MarginFCF / Revenue | — | 21.9% |
| Capex IntensityCapex / Revenue | — | 21.9% |
| Cash ConversionOCF / Net Profit | -0.18× | 0.95× |
| TTM Free Cash FlowTrailing 4 quarters | — | $1.0B |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-48.7M | $346.2M | ||
| Q3 25 | $74.3M | $562.1M | ||
| Q2 25 | $64.0M | $191.7M | ||
| Q1 25 | $20.3M | $461.2M | ||
| Q4 24 | $40.4M | $341.2M | ||
| Q3 24 | $63.2M | $377.2M | ||
| Q2 24 | $25.0M | $232.2M | ||
| Q1 24 | $29.1M | $376.5M |
| Q4 25 | — | $173.3M | ||
| Q3 25 | $73.9M | $351.6M | ||
| Q2 25 | — | $129.5M | ||
| Q1 25 | — | $386.3M | ||
| Q4 24 | — | $254.5M | ||
| Q3 24 | $63.2M | $300.7M | ||
| Q2 24 | — | $187.1M | ||
| Q1 24 | — | $338.3M |
| Q4 25 | — | 21.9% | ||
| Q3 25 | 26.5% | 44.0% | ||
| Q2 25 | — | 16.2% | ||
| Q1 25 | — | 48.6% | ||
| Q4 24 | — | 34.6% | ||
| Q3 24 | 25.2% | 40.2% | ||
| Q2 24 | — | 26.2% | ||
| Q1 24 | — | 49.9% |
| Q4 25 | — | 21.9% | ||
| Q3 25 | 0.1% | 26.3% | ||
| Q2 25 | — | 7.8% | ||
| Q1 25 | — | 9.4% | ||
| Q4 24 | — | 11.8% | ||
| Q3 24 | 0.0% | 10.2% | ||
| Q2 24 | — | 6.3% | ||
| Q1 24 | — | 5.6% |
| Q4 25 | -0.18× | 0.95× | ||
| Q3 25 | 1.03× | 1.66× | ||
| Q2 25 | 2.40× | 0.62× | ||
| Q1 25 | 1.07× | 1.43× | ||
| Q4 24 | 0.28× | 1.13× | ||
| Q3 24 | 1.93× | 1.22× | ||
| Q2 24 | 0.75× | 0.83× | ||
| Q1 24 | 1.76× | 1.23× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ACAD
| Nuplazid | $174.4M | 61% |
| Daybue | $109.6M | 39% |
UTHR
| Tyvaso DPI | $338.6M | 43% |
| Remodulin | $128.0M | 16% |
| Nebulized Tyvaso | $125.7M | 16% |
| Orenitram | $121.2M | 15% |
| Unituxin | $62.3M | 8% |
| Adcirca | $7.8M | 1% |
| Other | $6.6M | 1% |
