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Side-by-side financial comparison of ACADIA PHARMACEUTICALS INC (ACAD) and Yatsen Holding Ltd (YSG). Click either name above to swap in a different company.
ACADIA PHARMACEUTICALS INC is the larger business by last-quarter revenue ($268.1M vs $164.2M, roughly 1.6× Yatsen Holding Ltd). ACADIA PHARMACEUTICALS INC runs the higher net margin — 1.4% vs -0.5%, a 1.8% gap on every dollar of revenue. Over the past eight quarters, Yatsen Holding Ltd's revenue compounded faster (24.5% CAGR vs 5.3%).
Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, San Diego, California.
Yatsen Holding Ltd is a leading China-based beauty and personal care group. It develops and sells cosmetics, skincare products and fragrances under brands including Perfect Diary, Little Ondine and Abby's Choice, with core markets in mainland China, Southeast Asia, targeting Gen Z and young adult consumers.
ACAD vs YSG — Head-to-Head
Income Statement — Q1 FY2026 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $268.1M | $164.2M |
| Net Profit | $3.6M | $-776.5K |
| Gross Margin | — | 77.8% |
| Operating Margin | -1.7% | -34.0% |
| Net Margin | 1.4% | -0.5% |
| Revenue YoY | 9.7% | — |
| Net Profit YoY | — | — |
| EPS (diluted) | $0.02 | — |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $268.1M | — | ||
| Q4 25 | $284.0M | $164.2M | ||
| Q3 25 | $278.6M | $95.1M | ||
| Q2 25 | $264.6M | $110.9M | ||
| Q1 25 | $244.3M | $106.6M | ||
| Q4 24 | $259.6M | $147.0M | ||
| Q3 24 | $250.4M | $102.3M | ||
| Q2 24 | $242.0M | $118.1M |
| Q1 26 | $3.6M | — | ||
| Q4 25 | $273.6M | $-776.5K | ||
| Q3 25 | $71.8M | $-17.0M | ||
| Q2 25 | $26.7M | $-11.9M | ||
| Q1 25 | $19.0M | $-17.2M | ||
| Q4 24 | $143.7M | $-67.7M | ||
| Q3 24 | $32.8M | $-28.2M | ||
| Q2 24 | $33.4M | $-14.9M |
| Q1 26 | — | — | ||
| Q4 25 | 90.8% | 77.8% | ||
| Q3 25 | 92.2% | 75.9% | ||
| Q2 25 | 92.2% | 76.7% | ||
| Q1 25 | 91.7% | 77.7% | ||
| Q4 24 | 91.6% | 73.7% | ||
| Q3 24 | 92.5% | 71.4% | ||
| Q2 24 | 92.5% | 74.7% |
| Q1 26 | -1.7% | — | ||
| Q4 25 | 6.1% | -34.0% | ||
| Q3 25 | 12.8% | -20.9% | ||
| Q2 25 | 12.2% | -17.0% | ||
| Q1 25 | 7.9% | -20.4% | ||
| Q4 24 | 59.1% | -50.3% | ||
| Q3 24 | 12.6% | -32.2% | ||
| Q2 24 | 12.6% | -15.7% |
| Q1 26 | 1.4% | — | ||
| Q4 25 | 96.3% | -0.5% | ||
| Q3 25 | 25.8% | -17.9% | ||
| Q2 25 | 10.1% | -10.8% | ||
| Q1 25 | 7.8% | -16.1% | ||
| Q4 24 | 55.4% | -46.1% | ||
| Q3 24 | 13.1% | -27.6% | ||
| Q2 24 | 13.8% | -12.6% |
| Q1 26 | $0.02 | — | ||
| Q4 25 | $1.61 | — | ||
| Q3 25 | $0.42 | — | ||
| Q2 25 | $0.16 | — | ||
| Q1 25 | $0.11 | — | ||
| Q4 24 | $0.86 | — | ||
| Q3 24 | $0.20 | — | ||
| Q2 24 | $0.20 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | — | $109.4M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | — | $428.9M |
| Total Assets | $1.6B | $550.1M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $177.7M | $109.4M | ||
| Q3 25 | $258.0M | $97.0M | ||
| Q2 25 | $253.6M | $133.1M | ||
| Q1 25 | $217.7M | $92.3M | ||
| Q4 24 | $319.6M | $112.0M | ||
| Q3 24 | $155.1M | $71.7M | ||
| Q2 24 | $177.1M | $109.6M |
| Q1 26 | — | — | ||
| Q4 25 | $1.2B | $428.9M | ||
| Q3 25 | $917.3M | $423.1M | ||
| Q2 25 | $822.4M | $431.5M | ||
| Q1 25 | $765.2M | $422.2M | ||
| Q4 24 | $732.8M | $418.1M | ||
| Q3 24 | $577.2M | $516.0M | ||
| Q2 24 | $516.7M | $519.4M |
| Q1 26 | $1.6B | — | ||
| Q4 25 | $1.6B | $550.1M | ||
| Q3 25 | $1.3B | $564.8M | ||
| Q2 25 | $1.2B | $564.4M | ||
| Q1 25 | $1.1B | $534.3M | ||
| Q4 24 | $1.2B | $544.0M | ||
| Q3 24 | $976.9M | $635.6M | ||
| Q2 24 | $914.1M | $635.8M |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
