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Side-by-side financial comparison of Alpha Cognition Inc. (ACOG) and Alector, Inc. (ALEC). Click either name above to swap in a different company.

Alector, Inc. is the larger business by last-quarter revenue ($6.2M vs $2.8M, roughly 2.2× Alpha Cognition Inc.). Alpha Cognition Inc. runs the higher net margin — -245.5% vs -597.5%, a 352.0% gap on every dollar of revenue.

Alector, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative immunotherapies for neurodegenerative diseases. Its product pipeline targets unmet medical needs including Alzheimer’s disease, frontotemporal dementia, and Parkinson’s disease, and it collaborates with global pharmaceutical partners to advance candidate therapies through clinical trials.

ACOG vs ALEC — Head-to-Head

Bigger by revenue
ALEC
ALEC
2.2× larger
ALEC
$6.2M
$2.8M
ACOG
Higher net margin
ACOG
ACOG
352.0% more per $
ACOG
-245.5%
-597.5%
ALEC

Income Statement — Q4 2025 vs Q4 2025

Metric
ACOG
ACOG
ALEC
ALEC
Revenue
$2.8M
$6.2M
Net Profit
$-6.9M
$-37.3M
Gross Margin
Operating Margin
-283.7%
-634.4%
Net Margin
-245.5%
-597.5%
Revenue YoY
-88.5%
Net Profit YoY
-1696.9%
EPS (diluted)
$-0.10
$-0.34

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ACOG
ACOG
ALEC
ALEC
Q4 25
$2.8M
$6.2M
Q3 25
$2.8M
$3.3M
Q2 25
$1.7M
$7.9M
Q1 25
$2.9M
$3.7M
Q4 24
$54.2M
Q3 24
$15.3M
Q2 24
$15.1M
Q1 24
$15.9M
Net Profit
ACOG
ACOG
ALEC
ALEC
Q4 25
$-6.9M
$-37.3M
Q3 25
$-1.3M
$-34.7M
Q2 25
$-10.5M
$-30.5M
Q1 25
$-2.0M
$-40.5M
Q4 24
$-2.1M
Q3 24
$-42.2M
Q2 24
$-38.7M
Q1 24
$-36.1M
Gross Margin
ACOG
ACOG
ALEC
ALEC
Q4 25
Q3 25
Q2 25
96.7%
Q1 25
99.6%
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
ACOG
ACOG
ALEC
ALEC
Q4 25
-283.7%
-634.4%
Q3 25
-187.0%
-1153.6%
Q2 25
-346.1%
-433.6%
Q1 25
-125.9%
-1216.5%
Q4 24
-13.4%
Q3 24
-315.7%
Q2 24
-302.4%
Q1 24
-275.0%
Net Margin
ACOG
ACOG
ALEC
ALEC
Q4 25
-245.5%
-597.5%
Q3 25
-46.4%
-1063.4%
Q2 25
-632.7%
-387.7%
Q1 25
-68.5%
-1101.6%
Q4 24
-3.8%
Q3 24
-275.2%
Q2 24
-256.4%
Q1 24
-227.0%
EPS (diluted)
ACOG
ACOG
ALEC
ALEC
Q4 25
$-0.10
$-0.34
Q3 25
$-0.30
$-0.34
Q2 25
$-0.65
$-0.30
Q1 25
$-0.13
$-0.41
Q4 24
$-0.02
Q3 24
$-0.43
Q2 24
$-0.40
Q1 24
$-0.38

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ACOG
ACOG
ALEC
ALEC
Cash + ST InvestmentsLiquidity on hand
$66.0M
$256.0M
Total DebtLower is stronger
$10.0M
Stockholders' EquityBook value
$62.5M
$30.6M
Total Assets
$79.7M
$293.2M
Debt / EquityLower = less leverage
0.33×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ACOG
ACOG
ALEC
ALEC
Q4 25
$66.0M
$256.0M
Q3 25
$35.4M
$291.1M
Q2 25
$39.4M
$307.3M
Q1 25
$45.5M
$354.6M
Q4 24
$413.4M
Q3 24
$457.2M
Q2 24
$503.3M
Q1 24
$562.1M
Total Debt
ACOG
ACOG
ALEC
ALEC
Q4 25
$10.0M
Q3 25
Q2 25
Q1 25
Q4 24
$10.0M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ACOG
ACOG
ALEC
ALEC
Q4 25
$62.5M
$30.6M
Q3 25
$33.9M
$57.7M
Q2 25
$31.9M
$71.2M
Q1 25
$40.8M
$94.6M
Q4 24
$126.8M
Q3 24
$118.9M
Q2 24
$150.6M
Q1 24
$178.9M
Total Assets
ACOG
ACOG
ALEC
ALEC
Q4 25
$79.7M
$293.2M
Q3 25
$46.3M
$335.3M
Q2 25
$45.1M
$356.4M
Q1 25
$48.6M
$408.3M
Q4 24
$468.3M
Q3 24
$516.0M
Q2 24
$570.7M
Q1 24
$635.5M
Debt / Equity
ACOG
ACOG
ALEC
ALEC
Q4 25
0.33×
Q3 25
Q2 25
Q1 25
Q4 24
0.08×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ACOG
ACOG
ALEC
ALEC
Operating Cash FlowLast quarter
$-6.9M
$-41.7M
Free Cash FlowOCF − Capex
$-7.1M
FCF MarginFCF / Revenue
-252.6%
Capex IntensityCapex / Revenue
5.3%
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-20.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ACOG
ACOG
ALEC
ALEC
Q4 25
$-6.9M
$-41.7M
Q3 25
$-5.3M
$-32.5M
Q2 25
$-6.1M
$-49.0M
Q1 25
$-2.0M
$-60.8M
Q4 24
$-55.0M
Q3 24
$-50.7M
Q2 24
$-62.8M
Q1 24
$-61.3M
Free Cash Flow
ACOG
ACOG
ALEC
ALEC
Q4 25
$-7.1M
Q3 25
$-5.4M
$-32.5M
Q2 25
$-6.1M
$-49.1M
Q1 25
$-2.1M
$-60.8M
Q4 24
$-55.2M
Q3 24
$-50.9M
Q2 24
$-63.1M
Q1 24
$-61.9M
FCF Margin
ACOG
ACOG
ALEC
ALEC
Q4 25
-252.6%
Q3 25
-188.8%
-997.6%
Q2 25
-370.9%
-623.0%
Q1 25
-72.0%
-1655.0%
Q4 24
-101.8%
Q3 24
-332.1%
Q2 24
-418.6%
Q1 24
-389.3%
Capex Intensity
ACOG
ACOG
ALEC
ALEC
Q4 25
5.3%
0.0%
Q3 25
2.6%
0.3%
Q2 25
0.5%
0.1%
Q1 25
2.2%
0.5%
Q4 24
0.3%
Q3 24
1.4%
Q2 24
2.2%
Q1 24
3.4%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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