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Side-by-side financial comparison of Aclarion, Inc. (ACON) and PROTHENA CORP PUBLIC LTD CO (PRTA). Click either name above to swap in a different company.

PROTHENA CORP PUBLIC LTD CO is the larger business by last-quarter revenue ($21.0K vs $18.5K, roughly 1.1× Aclarion, Inc.). On growth, Aclarion, Inc. posted the faster year-over-year revenue change (80.6% vs -99.0%). Over the past eight quarters, Aclarion, Inc.'s revenue compounded faster (35.2% CAGR vs -35.2%).

Aclarion, Inc. is a medical technology company focused on developing non-invasive solutions for chronic lower back pain diagnosis and treatment. Its core offerings leverage proprietary magnetic resonance spectroscopy technology to accurately identify painful intervertebral discs, serving healthcare providers and patients across the United States, with key focus on the chronic pain management and spinal care segments.

Prothena Corporation plc is a late-stage clinical biotechnology firm focused on developing and commercializing innovative antibody therapies for neurodegenerative disorders, rare diseases and immune-related conditions. Its core pipeline targets unmet medical needs including amyloidosis, Parkinson's and Alzheimer's, serving key markets across North America, Europe and the Asia-Pacific.

ACON vs PRTA — Head-to-Head

Bigger by revenue
PRTA
PRTA
1.1× larger
PRTA
$21.0K
$18.5K
ACON
Growing faster (revenue YoY)
ACON
ACON
+179.6% gap
ACON
80.6%
-99.0%
PRTA
Faster 2-yr revenue CAGR
ACON
ACON
Annualised
ACON
35.2%
-35.2%
PRTA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ACON
ACON
PRTA
PRTA
Revenue
$18.5K
$21.0K
Net Profit
$-1.9M
Gross Margin
9.7%
Operating Margin
-10785.8%
Net Margin
-10223.7%
Revenue YoY
80.6%
-99.0%
Net Profit YoY
5.0%
62.7%
EPS (diluted)
$1.39

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ACON
ACON
PRTA
PRTA
Q4 25
$18.5K
$21.0K
Q3 25
$18.9K
$2.4M
Q2 25
$19.3K
$4.4M
Q1 25
$19.0K
$2.8M
Q4 24
$10.2K
$2.1M
Q3 24
$14.4K
$970.0K
Q2 24
$11.0K
$132.0M
Q1 24
$10.1K
$50.0K
Net Profit
ACON
ACON
PRTA
PRTA
Q4 25
$-1.9M
Q3 25
$-1.7M
$-36.5M
Q2 25
$-1.6M
$-125.8M
Q1 25
$-2.0M
$-60.2M
Q4 24
$-2.0M
Q3 24
$-1.4M
$-59.0M
Q2 24
$-1.2M
$66.9M
Q1 24
$-2.4M
$-72.2M
Gross Margin
ACON
ACON
PRTA
PRTA
Q4 25
9.7%
Q3 25
23.2%
Q2 25
26.6%
Q1 25
-23.6%
Q4 24
-100.9%
Q3 24
-48.1%
Q2 24
-112.3%
Q1 24
-92.6%
Operating Margin
ACON
ACON
PRTA
PRTA
Q4 25
-10785.8%
Q3 25
-9666.2%
-1666.3%
Q2 25
-8988.6%
-1914.4%
Q1 25
-7856.0%
-2319.0%
Q4 24
-17652.7%
Q3 24
-8995.3%
-6857.0%
Q2 24
-10350.6%
44.2%
Q1 24
-12609.3%
-163056.0%
Net Margin
ACON
ACON
PRTA
PRTA
Q4 25
-10223.7%
Q3 25
-9008.0%
-1513.1%
Q2 25
-8285.9%
-2845.4%
Q1 25
-10728.4%
-2128.5%
Q4 24
-19444.6%
Q3 24
-9482.7%
-6082.6%
Q2 24
-11285.0%
50.7%
Q1 24
-23720.6%
-144478.0%
EPS (diluted)
ACON
ACON
PRTA
PRTA
Q4 25
$1.39
Q3 25
$-2.93
$-0.68
Q2 25
$-2.75
$-2.34
Q1 25
$-9.32
$-1.12
Q4 24
$-809.36
Q3 24
$-1321.49
$-1.10
Q2 24
$-1362.83
$1.22
Q1 24
$-3985.22
$-1.34

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ACON
ACON
PRTA
PRTA
Cash + ST InvestmentsLiquidity on hand
$12.0M
$307.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$12.8M
$280.5M
Total Assets
$13.7M
$326.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ACON
ACON
PRTA
PRTA
Q4 25
$12.0M
$307.5M
Q3 25
$11.3M
$330.8M
Q2 25
$12.8M
$371.4M
Q1 25
$14.8M
$417.9M
Q4 24
$453.7K
$471.4M
Q3 24
$1.3M
$519.3M
Q2 24
$1.2M
$564.1M
Q1 24
$2.1M
$546.5M
Stockholders' Equity
ACON
ACON
PRTA
PRTA
Q4 25
$12.8M
$280.5M
Q3 25
$12.5M
$295.0M
Q2 25
$14.2M
$324.3M
Q1 25
$15.8M
$437.7M
Q4 24
$970.1K
$486.9M
Q3 24
$2.5M
$534.4M
Q2 24
$1.6M
$581.9M
Q1 24
$2.5M
$502.4M
Total Assets
ACON
ACON
PRTA
PRTA
Q4 25
$13.7M
$326.8M
Q3 25
$13.2M
$352.6M
Q2 25
$14.8M
$399.1M
Q1 25
$16.5M
$495.3M
Q4 24
$2.1M
$547.1M
Q3 24
$3.2M
$595.3M
Q2 24
$3.1M
$645.6M
Q1 24
$3.7M
$623.2M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ACON
ACON
PRTA
PRTA
Operating Cash FlowLast quarter
$-1.6M
$-163.6M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ACON
ACON
PRTA
PRTA
Q4 25
$-1.6M
$-163.6M
Q3 25
$-1.2M
$-40.6M
Q2 25
$-1.9M
$-46.3M
Q1 25
$-2.5M
$-53.4M
Q4 24
$-922.9K
$-150.1M
Q3 24
$-1.1M
$-45.2M
Q2 24
$-1.1M
$16.0M
Q1 24
$-2.2M
$-73.1M
Free Cash Flow
ACON
ACON
PRTA
PRTA
Q4 25
Q3 25
$-1.2M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
FCF Margin
ACON
ACON
PRTA
PRTA
Q4 25
Q3 25
-6164.6%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Capex Intensity
ACON
ACON
PRTA
PRTA
Q4 25
Q3 25
38.6%
Q2 25
Q1 25
Q4 24
Q3 24
0.0%
Q2 24
Q1 24
Cash Conversion
ACON
ACON
PRTA
PRTA
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.24×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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