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Side-by-side financial comparison of Enact Holdings, Inc. (ACT) and Royalty Pharma plc (RPRX). Click either name above to swap in a different company.

Royalty Pharma plc is the larger business by last-quarter revenue ($622.0M vs $312.7M, roughly 2.0× Enact Holdings, Inc.). On growth, Royalty Pharma plc posted the faster year-over-year revenue change (4.8% vs 3.6%). Over the past eight quarters, Royalty Pharma plc's revenue compounded faster (4.6% CAGR vs 3.6%).

Enact Holdings, Inc. is a leading U.S.-based private mortgage insurance provider. It delivers risk mitigation solutions to residential mortgage lenders, banks, and credit unions, enabling borrowers with smaller down payments to access affordable home financing, and supports sustainable homeownership for diverse consumer groups across the United States.

Acceleron Pharma, Inc. is an American clinical stage biopharmaceutical company based in Cambridge, Massachusetts with a broad focus on developing medicines that regulate the transforming growth factor beta (TGF-β) superfamily of proteins, which play fundamental roles in the growth and repair of cells and tissues such as red blood cells, muscle, bone, and blood vessels.

ACT vs RPRX — Head-to-Head

Bigger by revenue
RPRX
RPRX
2.0× larger
RPRX
$622.0M
$312.7M
ACT
Growing faster (revenue YoY)
RPRX
RPRX
+1.2% gap
RPRX
4.8%
3.6%
ACT
Faster 2-yr revenue CAGR
RPRX
RPRX
Annualised
RPRX
4.6%
3.6%
ACT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ACT
ACT
RPRX
RPRX
Revenue
$312.7M
$622.0M
Net Profit
$214.2M
Gross Margin
Operating Margin
71.3%
62.4%
Net Margin
34.4%
Revenue YoY
3.6%
4.8%
Net Profit YoY
2.9%
EPS (diluted)
$1.23
$0.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ACT
ACT
RPRX
RPRX
Q4 25
$312.7M
$622.0M
Q3 25
$311.5M
$609.3M
Q2 25
$304.9M
$578.7M
Q1 25
$306.8M
$568.2M
Q4 24
$301.8M
$593.6M
Q3 24
$309.6M
$564.7M
Q2 24
$298.8M
$537.3M
Q1 24
$291.6M
$568.0M
Net Profit
ACT
ACT
RPRX
RPRX
Q4 25
$214.2M
Q3 25
$288.2M
Q2 25
$30.2M
Q1 25
$238.3M
Q4 24
$208.2M
Q3 24
$544.0M
Q2 24
$102.0M
Q1 24
$4.8M
Operating Margin
ACT
ACT
RPRX
RPRX
Q4 25
71.3%
62.4%
Q3 25
67.4%
70.1%
Q2 25
70.4%
36.3%
Q1 25
68.9%
94.0%
Q4 24
68.9%
60.9%
Q3 24
74.1%
Q2 24
78.6%
50.2%
Q1 24
70.6%
-13.0%
Net Margin
ACT
ACT
RPRX
RPRX
Q4 25
34.4%
Q3 25
47.3%
Q2 25
5.2%
Q1 25
41.9%
Q4 24
35.1%
Q3 24
96.3%
Q2 24
19.0%
Q1 24
0.8%
EPS (diluted)
ACT
ACT
RPRX
RPRX
Q4 25
$1.23
$0.49
Q3 25
$1.10
$0.67
Q2 25
$1.11
$0.07
Q1 25
$1.08
$0.55
Q4 24
$1.05
$0.46
Q3 24
$1.15
$1.21
Q2 24
$1.16
$0.23
Q1 24
$1.01
$0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ACT
ACT
RPRX
RPRX
Cash + ST InvestmentsLiquidity on hand
$582.5M
$618.7M
Total DebtLower is stronger
$744.5M
$9.0B
Stockholders' EquityBook value
$5.4B
$9.7B
Total Assets
$6.9B
$19.6B
Debt / EquityLower = less leverage
0.14×
0.92×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ACT
ACT
RPRX
RPRX
Q4 25
$582.5M
$618.7M
Q3 25
$545.6M
$938.9M
Q2 25
$616.0M
$631.9M
Q1 25
$639.0M
$1.1B
Q4 24
$602.8M
$929.0M
Q3 24
$674.9M
$950.1M
Q2 24
$711.3M
$1.8B
Q1 24
$624.3M
$843.0M
Total Debt
ACT
ACT
RPRX
RPRX
Q4 25
$744.5M
$9.0B
Q3 25
$744.1M
$8.9B
Q2 25
$743.8M
$8.0B
Q1 25
$743.4M
$7.6B
Q4 24
$743.0M
$7.6B
Q3 24
$742.7M
$7.6B
Q2 24
$742.4M
$7.6B
Q1 24
$746.1M
$6.1B
Stockholders' Equity
ACT
ACT
RPRX
RPRX
Q4 25
$5.4B
$9.7B
Q3 25
$5.3B
$9.6B
Q2 25
$5.2B
$9.5B
Q1 25
$5.1B
$9.8B
Q4 24
$5.0B
$10.3B
Q3 24
$5.0B
$10.3B
Q2 24
$4.8B
$9.8B
Q1 24
$4.7B
$9.9B
Total Assets
ACT
ACT
RPRX
RPRX
Q4 25
$6.9B
$19.6B
Q3 25
$6.9B
$19.3B
Q2 25
$6.8B
$18.3B
Q1 25
$6.7B
$17.6B
Q4 24
$6.5B
$18.2B
Q3 24
$6.6B
$18.0B
Q2 24
$6.3B
$17.7B
Q1 24
$6.3B
$16.1B
Debt / Equity
ACT
ACT
RPRX
RPRX
Q4 25
0.14×
0.92×
Q3 25
0.14×
0.93×
Q2 25
0.14×
0.84×
Q1 25
0.15×
0.78×
Q4 24
0.15×
0.74×
Q3 24
0.15×
0.74×
Q2 24
0.15×
0.78×
Q1 24
0.16×
0.62×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ACT
ACT
RPRX
RPRX
Operating Cash FlowLast quarter
$724.5M
$827.1M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
3.86×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ACT
ACT
RPRX
RPRX
Q4 25
$724.5M
$827.1M
Q3 25
$192.0M
$702.6M
Q2 25
$119.5M
$364.0M
Q1 25
$226.7M
$596.1M
Q4 24
$686.3M
$742.5M
Q3 24
$188.1M
$703.6M
Q2 24
$144.7M
$658.2M
Q1 24
$187.3M
$664.6M
Cash Conversion
ACT
ACT
RPRX
RPRX
Q4 25
3.86×
Q3 25
2.44×
Q2 25
12.06×
Q1 25
2.50×
Q4 24
3.57×
Q3 24
1.29×
Q2 24
6.45×
Q1 24
139.10×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ACT
ACT

Segment breakdown not available.

RPRX
RPRX

Financial Royalty Assets$592.4M95%
Royalty Income Other$29.6M5%

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