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Side-by-side financial comparison of Aflac (AFL) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Aflac is the larger business by last-quarter revenue ($4.3B vs $3.0B, roughly 1.5× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs 23.4%, a 11.1% gap on every dollar of revenue. On growth, Aflac posted the faster year-over-year revenue change (27.9% vs 7.8%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (6.3% CAGR vs -8.0%).

Aflac Incorporated is an American insurance company and is the largest provider of supplemental insurance in the United States. It was founded in 1955 and is based in Columbus, Georgia. In the U.S., it underwrites a wide range of insurance policies, but is perhaps more known for its payroll deduction insurance coverage, which pays cash benefits when a policyholder has a covered accident or illness. The company states it "provides financial protection to more than 50 million people worldwide".

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

AFL vs VRTX — Head-to-Head

Bigger by revenue
AFL
AFL
1.5× larger
AFL
$4.3B
$3.0B
VRTX
Growing faster (revenue YoY)
AFL
AFL
+20.1% gap
AFL
27.9%
7.8%
VRTX
Higher net margin
VRTX
VRTX
11.1% more per $
VRTX
34.5%
23.4%
AFL
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
6.3%
-8.0%
AFL

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
AFL
AFL
VRTX
VRTX
Revenue
$4.3B
$3.0B
Net Profit
$1.0B
$1.0B
Gross Margin
86.8%
Operating Margin
38.1%
Net Margin
23.4%
34.5%
Revenue YoY
27.9%
7.8%
Net Profit YoY
59.6%
EPS (diluted)
$1.98
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AFL
AFL
VRTX
VRTX
Q1 26
$4.3B
$3.0B
Q4 25
$4.9B
$3.2B
Q3 25
$4.7B
$3.1B
Q2 25
$4.2B
$3.0B
Q1 25
$3.4B
$2.8B
Q4 24
$5.4B
$2.9B
Q3 24
$2.9B
$2.8B
Q2 24
$5.1B
$2.6B
Net Profit
AFL
AFL
VRTX
VRTX
Q1 26
$1.0B
$1.0B
Q4 25
$1.4B
$1.2B
Q3 25
$1.6B
$1.1B
Q2 25
$599.0M
$1.0B
Q1 25
$29.0M
$646.3M
Q4 24
$1.9B
$913.0M
Q3 24
$-93.0M
$1.0B
Q2 24
$1.8B
$-3.6B
Gross Margin
AFL
AFL
VRTX
VRTX
Q1 26
86.8%
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
AFL
AFL
VRTX
VRTX
Q1 26
38.1%
Q4 25
32.3%
37.8%
Q3 25
42.1%
38.6%
Q2 25
19.8%
38.8%
Q1 25
4.3%
22.7%
Q4 24
39.5%
35.2%
Q3 24
3.1%
40.3%
Q2 24
39.3%
-132.9%
Net Margin
AFL
AFL
VRTX
VRTX
Q1 26
23.4%
34.5%
Q4 25
28.3%
37.3%
Q3 25
34.6%
35.2%
Q2 25
14.4%
34.8%
Q1 25
0.9%
23.3%
Q4 24
35.2%
31.4%
Q3 24
-3.2%
37.7%
Q2 24
34.2%
-135.8%
EPS (diluted)
AFL
AFL
VRTX
VRTX
Q1 26
$1.98
$4.02
Q4 25
$2.58
$4.64
Q3 25
$3.08
$4.20
Q2 25
$1.11
$3.99
Q1 25
$0.05
$2.49
Q4 24
$3.45
$3.62
Q3 24
$-0.17
$4.01
Q2 24
$3.10
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AFL
AFL
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$5.1B
Total DebtLower is stronger
Stockholders' EquityBook value
$30.0B
$19.4B
Total Assets
$116.3B
$26.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AFL
AFL
VRTX
VRTX
Q1 26
$5.1B
Q4 25
$6.2B
$6.6B
Q3 25
$6.8B
$6.3B
Q2 25
$7.0B
$6.4B
Q1 25
$5.2B
$6.2B
Q4 24
$6.2B
$6.1B
Q3 24
$5.6B
$6.5B
Q2 24
$6.1B
$5.8B
Stockholders' Equity
AFL
AFL
VRTX
VRTX
Q1 26
$30.0B
$19.4B
Q4 25
$29.5B
$18.7B
Q3 25
$28.7B
$17.3B
Q2 25
$27.2B
$17.2B
Q1 25
$26.3B
$16.5B
Q4 24
$26.1B
$16.4B
Q3 24
$24.8B
$15.6B
Q2 24
$26.0B
$14.8B
Total Assets
AFL
AFL
VRTX
VRTX
Q1 26
$116.3B
$26.5B
Q4 25
$116.5B
$25.6B
Q3 25
$122.3B
$24.9B
Q2 25
$124.7B
$24.0B
Q1 25
$120.3B
$22.9B
Q4 24
$117.6B
$22.5B
Q3 24
$128.4B
$22.2B
Q2 24
$120.2B
$20.1B

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AFL
AFL

Segment breakdown not available.

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

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