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Side-by-side financial comparison of AGENUS INC (AGEN) and Orchid Island Capital, Inc. (ORC). Click either name above to swap in a different company.

Orchid Island Capital, Inc. is the larger business by last-quarter revenue ($38.5M vs $34.2M, roughly 1.1× AGENUS INC). Orchid Island Capital, Inc. runs the higher net margin — 268.7% vs -31.0%, a 299.7% gap on every dollar of revenue. On growth, Orchid Island Capital, Inc. posted the faster year-over-year revenue change (372.6% vs 27.5%). Over the past eight quarters, Orchid Island Capital, Inc.'s revenue compounded faster (301.6% CAGR vs 10.5%).

Agenus Inc. is a Lexington, Massachusetts-based biotechnology company focused on immunotherapy including immuno-oncology, a field that uses the immune system to control or cure cancer. The company is developing checkpoint modulators (CPMs), patient-specific anti-cancer vaccines, and adjuvants designed for use with various vaccines. CPM development is a particularly fast-moving field, since early products have produced unprecedented clinical benefits for patients.

Orchid Island Capital, Inc. is a U.S.-based specialty finance company operating as a real estate investment trust. It primarily invests in residential mortgage-backed securities, including agency and non-agency products, targeting consistent risk-adjusted returns for its investors across U.S. fixed income markets.

AGEN vs ORC — Head-to-Head

Bigger by revenue
ORC
ORC
1.1× larger
ORC
$38.5M
$34.2M
AGEN
Growing faster (revenue YoY)
ORC
ORC
+345.1% gap
ORC
372.6%
27.5%
AGEN
Higher net margin
ORC
ORC
299.7% more per $
ORC
268.7%
-31.0%
AGEN
Faster 2-yr revenue CAGR
ORC
ORC
Annualised
ORC
301.6%
10.5%
AGEN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AGEN
AGEN
ORC
ORC
Revenue
$34.2M
$38.5M
Net Profit
$-10.6M
$103.4M
Gross Margin
Operating Margin
42.1%
Net Margin
-31.0%
268.7%
Revenue YoY
27.5%
372.6%
Net Profit YoY
77.3%
1764.9%
EPS (diluted)
$0.09

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGEN
AGEN
ORC
ORC
Q4 25
$34.2M
$38.5M
Q3 25
$30.2M
$26.9M
Q2 25
$25.7M
$23.2M
Q1 25
$24.1M
$19.7M
Q4 24
$26.8M
Q3 24
$25.1M
$340.0K
Q2 24
$23.5M
$-697.0K
Q1 24
$28.0M
$-2.5M
Net Profit
AGEN
AGEN
ORC
ORC
Q4 25
$-10.6M
$103.4M
Q3 25
$63.9M
$72.1M
Q2 25
$-30.0M
$-33.6M
Q1 25
$-26.4M
$17.1M
Q4 24
$-46.8M
Q3 24
$-67.2M
$17.3M
Q2 24
$-54.8M
$-5.0M
Q1 24
$-63.5M
$19.8M
Gross Margin
AGEN
AGEN
ORC
ORC
Q4 25
Q3 25
97.9%
Q2 25
99.1%
Q1 25
99.4%
Q4 24
99.6%
Q3 24
99.4%
Q2 24
99.5%
Q1 24
99.6%
Operating Margin
AGEN
AGEN
ORC
ORC
Q4 25
42.1%
Q3 25
-15.0%
Q2 25
-65.0%
Q1 25
-55.3%
Q4 24
-96.5%
Q3 24
-125.5%
Q2 24
-128.4%
Q1 24
-117.4%
Net Margin
AGEN
AGEN
ORC
ORC
Q4 25
-31.0%
268.7%
Q3 25
211.4%
267.8%
Q2 25
-116.8%
-145.0%
Q1 25
-109.6%
86.9%
Q4 24
-174.4%
Q3 24
-267.7%
5094.1%
Q2 24
-233.1%
714.3%
Q1 24
-226.6%
-794.2%
EPS (diluted)
AGEN
AGEN
ORC
ORC
Q4 25
$0.09
Q3 25
$1.94
Q2 25
$-1.00
Q1 25
$-1.03
Q4 24
$-1.95
Q3 24
$-3.08
Q2 24
$-2.52
Q1 24
$-3.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGEN
AGEN
ORC
ORC
Cash + ST InvestmentsLiquidity on hand
$3.0M
$665.9M
Total DebtLower is stronger
$44.7M
Stockholders' EquityBook value
$-271.1M
$1.4B
Total Assets
$226.8M
$11.7B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGEN
AGEN
ORC
ORC
Q4 25
$3.0M
$665.9M
Q3 25
$3.5M
$583.9M
Q2 25
$9.5M
$440.8M
Q1 25
$18.5M
$396.4M
Q4 24
$40.4M
Q3 24
$44.8M
$322.1M
Q2 24
$93.7M
$241.0M
Q1 24
$52.9M
$190.4M
Total Debt
AGEN
AGEN
ORC
ORC
Q4 25
$44.7M
Q3 25
$34.2M
Q2 25
$33.9M
Q1 25
$33.6M
Q4 24
$33.2M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
AGEN
AGEN
ORC
ORC
Q4 25
$-271.1M
$1.4B
Q3 25
$-274.1M
$1.1B
Q2 25
$-354.6M
$912.0M
Q1 25
$-341.8M
$855.9M
Q4 24
$-326.4M
Q3 24
$-292.3M
$656.0M
Q2 24
$-241.3M
$555.9M
Q1 24
$-201.4M
$481.6M
Total Assets
AGEN
AGEN
ORC
ORC
Q4 25
$226.8M
$11.7B
Q3 25
$233.9M
$9.1B
Q2 25
$185.2M
$7.6B
Q1 25
$200.2M
$7.3B
Q4 24
$226.3M
Q3 24
$238.5M
$5.9B
Q2 24
$292.4M
$4.9B
Q1 24
$256.6M
$4.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGEN
AGEN
ORC
ORC
Operating Cash FlowLast quarter
$-16.6M
$120.4M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
1.16×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGEN
AGEN
ORC
ORC
Q4 25
$-16.6M
$120.4M
Q3 25
$-14.7M
$28.0M
Q2 25
$-20.2M
$18.4M
Q1 25
$-25.6M
$25.8M
Q4 24
$-28.7M
Q3 24
$-53.3M
$-14.8M
Q2 24
$-38.2M
$19.3M
Q1 24
$-38.2M
$45.0M
Free Cash Flow
AGEN
AGEN
ORC
ORC
Q4 25
Q3 25
Q2 25
$-20.2M
Q1 25
$-25.6M
Q4 24
$-28.7M
Q3 24
$-53.3M
Q2 24
$-38.6M
Q1 24
$-38.2M
FCF Margin
AGEN
AGEN
ORC
ORC
Q4 25
Q3 25
Q2 25
-78.7%
Q1 25
-106.5%
Q4 24
-107.0%
Q3 24
-212.2%
Q2 24
-164.4%
Q1 24
-136.5%
Capex Intensity
AGEN
AGEN
ORC
ORC
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.0%
Q1 25
0.0%
Q4 24
0.3%
Q3 24
0.0%
Q2 24
2.0%
Q1 24
0.1%
Cash Conversion
AGEN
AGEN
ORC
ORC
Q4 25
1.16×
Q3 25
-0.23×
0.39×
Q2 25
Q1 25
1.51×
Q4 24
Q3 24
-0.86×
Q2 24
Q1 24
2.28×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AGEN
AGEN

Non Cash Royalty Revenue$31.1M91%
Other$3.2M9%

ORC
ORC

Segment breakdown not available.

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