AGENUS INC

AGENUS INCAGENEarnings & Financial Report

Nasdaq · Health Care · Biological Products, (No Diagnostic Substances)

Agenus Inc. is a Lexington, Massachusetts-based biotechnology company focused on immunotherapy including immuno-oncology, a field that uses the immune system to control or cure cancer. The company is developing checkpoint modulators (CPMs), patient-specific anti-cancer vaccines, and adjuvants designed for use with various vaccines. CPM development is a particularly fast-moving field, since early products have produced unprecedented clinical benefits for patients.

AGEN Q4 FY2025 Key Financial Metrics

Revenue

$34.2M

Gross Profit

N/A

Operating Profit

$14.4M

Net Profit

$-10.6M

Gross Margin

N/A

Operating Margin

42.1%

Net Margin

-31.0%

YoY Growth

27.5%

EPS

$0.09

AGENUS INC Q4 FY2025 Financial Summary

AGENUS INC reported revenue of $34.2M (up 27.5% YoY) for Q4 FY2025, with a net profit of $-10.6M (up 77.3% YoY) (-31.0% margin).

Key Financial Metrics

Total Revenue$34.2M
Net Profit$-10.6M
Gross MarginN/A
Operating Margin42.1%
Report PeriodQ4 FY2025

Revenue Breakdown

AGENUS INC Q4 FY2025 revenue of $34.2M breaks down across 2 segments, led by Non Cash Royalty Revenue at $31.1M (90.8% of total).

SegmentRevenue% of Total
Non Cash Royalty Revenue$31.1M90.8%
Other$3.2M9.2%

AGENUS INC Revenue by Segment — Quarterly Trend

AGENUS INC revenue by segment across the last 4 reported quarters, showing how each business line (such as Non Cash Royalty Revenue and Other) has evolved quarter over quarter.

SegmentQ4 FY2025Q3 FY2025Q2 FY2025Q1 FY2025
Non Cash Royalty Revenue$31.1M
Other$3.2M$860.0K$510.0K

AGENUS INC Annual Revenue by Year

AGENUS INC annual revenue history includes year-by-year totals (for example, 2025 revenue was $114.2M).

YearAnnual Revenue
2025$114.2Mvs 2024
2024$103.5Mvs 2023
2023$156.3Mvs 2022
2022$98.0M

AGENUS INC Quarterly Revenue & Net Profit History

AGENUS INC results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 FY2025$34.2M+27.5%$-10.6M-31.0%
Q3 FY2025$30.2M+20.4%$63.9M211.4%
Q2 FY2025$25.7M+9.3%$-30.0M-116.8%
Q1 FY2025$24.1M-14.1%$-26.4M-109.6%
Q4 FY2024$26.8M-68.0%$-46.8M-174.4%
Q3 FY2024$25.1M+3.3%$-67.2M-267.7%
Q2 FY2024$23.5M-7.1%$-54.8M-233.1%
Q1 FY2024$28.0M+22.3%$-63.5M-226.6%

Income Statement

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Revenue$28.0M$23.5M$25.1M$26.8M$24.1M$25.7M$30.2M$34.2M
YoY Growth22.3%-7.1%3.3%-68.0%-14.1%9.3%20.4%27.5%

Balance Sheet

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Assets$256.6M$292.4M$238.5M$226.3M$200.2M$185.2M$233.9M$226.8M
Liabilities$458.0M$533.7M$530.8M$552.7M$542.0M$539.8M$508.0M$497.9M
Equity$-201.4M$-241.3M$-292.3M$-326.4M$-341.8M$-354.6M$-274.1M$-271.1M

Cash Flow

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$-38.2M$-38.2M$-53.3M$-28.7M$-25.6M$-20.2M$-14.7M$-16.6M