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Side-by-side financial comparison of AGENUS INC (AGEN) and Star Equity Holdings, Inc. (STRR). Click either name above to swap in a different company.

Star Equity Holdings, Inc. is the larger business by last-quarter revenue ($56.8M vs $34.2M, roughly 1.7× AGENUS INC). Star Equity Holdings, Inc. runs the higher net margin — -3.0% vs -31.0%, a 28.0% gap on every dollar of revenue. On growth, Star Equity Holdings, Inc. posted the faster year-over-year revenue change (69.0% vs 27.5%). Over the past eight quarters, Star Equity Holdings, Inc.'s revenue compounded faster (29.5% CAGR vs 10.5%).

Agenus Inc. is a Lexington, Massachusetts-based biotechnology company focused on immunotherapy including immuno-oncology, a field that uses the immune system to control or cure cancer. The company is developing checkpoint modulators (CPMs), patient-specific anti-cancer vaccines, and adjuvants designed for use with various vaccines. CPM development is a particularly fast-moving field, since early products have produced unprecedented clinical benefits for patients.

Artists Equity is an American production company founded by actors and filmmakers Ben Affleck and Matt Damon in November 2022.

AGEN vs STRR — Head-to-Head

Bigger by revenue
STRR
STRR
1.7× larger
STRR
$56.8M
$34.2M
AGEN
Growing faster (revenue YoY)
STRR
STRR
+41.6% gap
STRR
69.0%
27.5%
AGEN
Higher net margin
STRR
STRR
28.0% more per $
STRR
-3.0%
-31.0%
AGEN
Faster 2-yr revenue CAGR
STRR
STRR
Annualised
STRR
29.5%
10.5%
AGEN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AGEN
AGEN
STRR
STRR
Revenue
$34.2M
$56.8M
Net Profit
$-10.6M
$-1.7M
Gross Margin
Operating Margin
42.1%
-0.2%
Net Margin
-31.0%
-3.0%
Revenue YoY
27.5%
69.0%
Net Profit YoY
77.3%
-192.1%
EPS (diluted)
$0.09
$-0.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGEN
AGEN
STRR
STRR
Q4 25
$34.2M
$56.8M
Q3 25
$30.2M
$48.0M
Q2 25
$25.7M
$35.5M
Q1 25
$24.1M
$31.9M
Q4 24
$26.8M
$33.6M
Q3 24
$25.1M
$36.9M
Q2 24
$23.5M
$35.7M
Q1 24
$28.0M
$33.9M
Net Profit
AGEN
AGEN
STRR
STRR
Q4 25
$-10.6M
$-1.7M
Q3 25
$63.9M
$-1.8M
Q2 25
$-30.0M
$-688.0K
Q1 25
$-26.4M
$-1.8M
Q4 24
$-46.8M
$-585.0K
Q3 24
$-67.2M
$-846.0K
Q2 24
$-54.8M
$-441.0K
Q1 24
$-63.5M
$-2.9M
Gross Margin
AGEN
AGEN
STRR
STRR
Q4 25
Q3 25
97.9%
43.0%
Q2 25
99.1%
Q1 25
99.4%
Q4 24
99.6%
Q3 24
99.4%
50.5%
Q2 24
99.5%
Q1 24
99.6%
Operating Margin
AGEN
AGEN
STRR
STRR
Q4 25
42.1%
-0.2%
Q3 25
-15.0%
-3.4%
Q2 25
-65.0%
-0.6%
Q1 25
-55.3%
-5.4%
Q4 24
-96.5%
-0.4%
Q3 24
-125.5%
-1.2%
Q2 24
-128.4%
-0.5%
Q1 24
-117.4%
-9.0%
Net Margin
AGEN
AGEN
STRR
STRR
Q4 25
-31.0%
-3.0%
Q3 25
211.4%
-3.7%
Q2 25
-116.8%
-1.9%
Q1 25
-109.6%
-5.5%
Q4 24
-174.4%
-1.7%
Q3 24
-267.7%
-2.3%
Q2 24
-233.1%
-1.2%
Q1 24
-226.6%
-8.6%
EPS (diluted)
AGEN
AGEN
STRR
STRR
Q4 25
$0.09
$-0.49
Q3 25
$1.94
$-0.54
Q2 25
$-1.00
$-0.23
Q1 25
$-1.03
$-0.59
Q4 24
$-1.95
$-0.21
Q3 24
$-3.08
$-0.28
Q2 24
$-2.52
$-0.15
Q1 24
$-3.04
$-0.95

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGEN
AGEN
STRR
STRR
Cash + ST InvestmentsLiquidity on hand
$3.0M
$10.3M
Total DebtLower is stronger
$44.7M
Stockholders' EquityBook value
$-271.1M
$65.7M
Total Assets
$226.8M
$113.2M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGEN
AGEN
STRR
STRR
Q4 25
$3.0M
$10.3M
Q3 25
$3.5M
$15.4M
Q2 25
$9.5M
$16.8M
Q1 25
$18.5M
$16.6M
Q4 24
$40.4M
$17.0M
Q3 24
$44.8M
$15.8M
Q2 24
$93.7M
$14.7M
Q1 24
$52.9M
$20.4M
Total Debt
AGEN
AGEN
STRR
STRR
Q4 25
$44.7M
Q3 25
$34.2M
$6.5M
Q2 25
$33.9M
Q1 25
$33.6M
Q4 24
$33.2M
$0
Q3 24
Q2 24
Q1 24
Stockholders' Equity
AGEN
AGEN
STRR
STRR
Q4 25
$-271.1M
$65.7M
Q3 25
$-274.1M
$67.8M
Q2 25
$-354.6M
$40.1M
Q1 25
$-341.8M
$39.5M
Q4 24
$-326.4M
$40.4M
Q3 24
$-292.3M
$42.9M
Q2 24
$-241.3M
$42.6M
Q1 24
$-201.4M
$44.3M
Total Assets
AGEN
AGEN
STRR
STRR
Q4 25
$226.8M
$113.2M
Q3 25
$233.9M
$117.1M
Q2 25
$185.2M
$55.6M
Q1 25
$200.2M
$53.2M
Q4 24
$226.3M
$52.6M
Q3 24
$238.5M
$52.6M
Q2 24
$292.4M
$52.6M
Q1 24
$256.6M
$52.6M
Debt / Equity
AGEN
AGEN
STRR
STRR
Q4 25
Q3 25
0.10×
Q2 25
Q1 25
Q4 24
0.00×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGEN
AGEN
STRR
STRR
Operating Cash FlowLast quarter
$-16.6M
$-7.3M
Free Cash FlowOCF − Capex
$-9.0M
FCF MarginFCF / Revenue
-15.8%
Capex IntensityCapex / Revenue
0.0%
3.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-13.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGEN
AGEN
STRR
STRR
Q4 25
$-16.6M
$-7.3M
Q3 25
$-14.7M
$-2.7M
Q2 25
$-20.2M
$139.0K
Q1 25
$-25.6M
$-802.0K
Q4 24
$-28.7M
$-2.8M
Q3 24
$-53.3M
$1.3M
Q2 24
$-38.2M
$-4.3M
Q1 24
$-38.2M
$-1.8M
Free Cash Flow
AGEN
AGEN
STRR
STRR
Q4 25
$-9.0M
Q3 25
$-3.4M
Q2 25
$-20.2M
$102.0K
Q1 25
$-25.6M
$-808.0K
Q4 24
$-28.7M
$-2.8M
Q3 24
$-53.3M
$1.3M
Q2 24
$-38.6M
$-4.3M
Q1 24
$-38.2M
$-1.8M
FCF Margin
AGEN
AGEN
STRR
STRR
Q4 25
-15.8%
Q3 25
-7.0%
Q2 25
-78.7%
0.3%
Q1 25
-106.5%
-2.5%
Q4 24
-107.0%
-8.3%
Q3 24
-212.2%
3.4%
Q2 24
-164.4%
-12.0%
Q1 24
-136.5%
-5.3%
Capex Intensity
AGEN
AGEN
STRR
STRR
Q4 25
0.0%
3.0%
Q3 25
0.0%
1.3%
Q2 25
0.0%
0.1%
Q1 25
0.0%
0.0%
Q4 24
0.3%
0.1%
Q3 24
0.0%
0.0%
Q2 24
2.0%
0.0%
Q1 24
0.1%
0.0%
Cash Conversion
AGEN
AGEN
STRR
STRR
Q4 25
Q3 25
-0.23×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AGEN
AGEN

Non Cash Royalty Revenue$31.1M91%
Other$3.2M9%

STRR
STRR

Revenue From Other Contracts With Customers$27.6M49%
Other$24.3M43%
Energy Services Segment$4.9M9%

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