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Side-by-side financial comparison of AGENUS INC (AGEN) and SYPRIS SOLUTIONS INC (SYPR). Click either name above to swap in a different company.

AGENUS INC is the larger business by last-quarter revenue ($34.2M vs $30.3M, roughly 1.1× SYPRIS SOLUTIONS INC). SYPRIS SOLUTIONS INC runs the higher net margin — -12.9% vs -31.0%, a 18.1% gap on every dollar of revenue. On growth, AGENUS INC posted the faster year-over-year revenue change (27.5% vs -9.5%). Over the past eight quarters, AGENUS INC's revenue compounded faster (10.5% CAGR vs -7.7%).

Agenus Inc. is a Lexington, Massachusetts-based biotechnology company focused on immunotherapy including immuno-oncology, a field that uses the immune system to control or cure cancer. The company is developing checkpoint modulators (CPMs), patient-specific anti-cancer vaccines, and adjuvants designed for use with various vaccines. CPM development is a particularly fast-moving field, since early products have produced unprecedented clinical benefits for patients.

Sypris Solutions Inc. is a U.S.-headquartered provider of highly engineered components and specialized technical services, primarily serving aerospace, defense, automotive and commercial industrial markets. It delivers custom manufacturing, performance testing, and value-added engineering support for mission-critical systems and parts for global enterprise clients.

AGEN vs SYPR — Head-to-Head

Bigger by revenue
AGEN
AGEN
1.1× larger
AGEN
$34.2M
$30.3M
SYPR
Growing faster (revenue YoY)
AGEN
AGEN
+36.9% gap
AGEN
27.5%
-9.5%
SYPR
Higher net margin
SYPR
SYPR
18.1% more per $
SYPR
-12.9%
-31.0%
AGEN
Faster 2-yr revenue CAGR
AGEN
AGEN
Annualised
AGEN
10.5%
-7.7%
SYPR

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AGEN
AGEN
SYPR
SYPR
Revenue
$34.2M
$30.3M
Net Profit
$-10.6M
$-3.9M
Gross Margin
4.6%
Operating Margin
42.1%
-10.9%
Net Margin
-31.0%
-12.9%
Revenue YoY
27.5%
-9.5%
Net Profit YoY
77.3%
-2992.6%
EPS (diluted)
$0.09
$-0.17

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGEN
AGEN
SYPR
SYPR
Q4 25
$34.2M
$30.3M
Q3 25
$30.2M
$28.7M
Q2 25
$25.7M
$31.4M
Q1 25
$24.1M
$29.5M
Q4 24
$26.8M
$33.4M
Q3 24
$25.1M
$35.7M
Q2 24
$23.5M
$35.5M
Q1 24
$28.0M
$35.6M
Net Profit
AGEN
AGEN
SYPR
SYPR
Q4 25
$-10.6M
$-3.9M
Q3 25
$63.9M
$517.0K
Q2 25
$-30.0M
$-2.1M
Q1 25
$-26.4M
$-899.0K
Q4 24
$-46.8M
$135.0K
Q3 24
$-67.2M
$390.0K
Q2 24
$-54.8M
$16.0K
Q1 24
$-63.5M
$-2.2M
Gross Margin
AGEN
AGEN
SYPR
SYPR
Q4 25
4.6%
Q3 25
97.9%
7.2%
Q2 25
99.1%
8.2%
Q1 25
99.4%
11.4%
Q4 24
99.6%
16.1%
Q3 24
99.4%
16.8%
Q2 24
99.5%
15.9%
Q1 24
99.6%
8.1%
Operating Margin
AGEN
AGEN
SYPR
SYPR
Q4 25
42.1%
-10.9%
Q3 25
-15.0%
-6.1%
Q2 25
-65.0%
-4.6%
Q1 25
-55.3%
-0.4%
Q4 24
-96.5%
3.9%
Q3 24
-125.5%
4.8%
Q2 24
-128.4%
3.6%
Q1 24
-117.4%
-3.9%
Net Margin
AGEN
AGEN
SYPR
SYPR
Q4 25
-31.0%
-12.9%
Q3 25
211.4%
1.8%
Q2 25
-116.8%
-6.5%
Q1 25
-109.6%
-3.0%
Q4 24
-174.4%
0.4%
Q3 24
-267.7%
1.1%
Q2 24
-233.1%
0.0%
Q1 24
-226.6%
-6.2%
EPS (diluted)
AGEN
AGEN
SYPR
SYPR
Q4 25
$0.09
$-0.17
Q3 25
$1.94
$0.02
Q2 25
$-1.00
$-0.09
Q1 25
$-1.03
$-0.04
Q4 24
$-1.95
$0.00
Q3 24
$-3.08
$0.02
Q2 24
$-2.52
$0.00
Q1 24
$-3.04
$-0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGEN
AGEN
SYPR
SYPR
Cash + ST InvestmentsLiquidity on hand
$3.0M
Total DebtLower is stronger
$44.7M
Stockholders' EquityBook value
$-271.1M
$17.8M
Total Assets
$226.8M
$107.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGEN
AGEN
SYPR
SYPR
Q4 25
$3.0M
Q3 25
$3.5M
Q2 25
$9.5M
Q1 25
$18.5M
Q4 24
$40.4M
Q3 24
$44.8M
Q2 24
$93.7M
Q1 24
$52.9M
Total Debt
AGEN
AGEN
SYPR
SYPR
Q4 25
$44.7M
Q3 25
$34.2M
Q2 25
$33.9M
Q1 25
$33.6M
Q4 24
$33.2M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
AGEN
AGEN
SYPR
SYPR
Q4 25
$-271.1M
$17.8M
Q3 25
$-274.1M
$20.0M
Q2 25
$-354.6M
$18.7M
Q1 25
$-341.8M
$19.0M
Q4 24
$-326.4M
$19.6M
Q3 24
$-292.3M
$18.2M
Q2 24
$-241.3M
$19.0M
Q1 24
$-201.4M
$20.8M
Total Assets
AGEN
AGEN
SYPR
SYPR
Q4 25
$226.8M
$107.8M
Q3 25
$233.9M
$112.5M
Q2 25
$185.2M
$105.8M
Q1 25
$200.2M
$110.2M
Q4 24
$226.3M
$119.4M
Q3 24
$238.5M
$121.6M
Q2 24
$292.4M
$124.2M
Q1 24
$256.6M
$129.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGEN
AGEN
SYPR
SYPR
Operating Cash FlowLast quarter
$-16.6M
$-1.1M
Free Cash FlowOCF − Capex
$-1.5M
FCF MarginFCF / Revenue
-5.0%
Capex IntensityCapex / Revenue
0.0%
1.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-6.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGEN
AGEN
SYPR
SYPR
Q4 25
$-16.6M
$-1.1M
Q3 25
$-14.7M
$-178.0K
Q2 25
$-20.2M
$1.1M
Q1 25
$-25.6M
$-5.5M
Q4 24
$-28.7M
$2.3M
Q3 24
$-53.3M
$-4.8M
Q2 24
$-38.2M
$6.2M
Q1 24
$-38.2M
$-1.7M
Free Cash Flow
AGEN
AGEN
SYPR
SYPR
Q4 25
$-1.5M
Q3 25
$-390.0K
Q2 25
$-20.2M
$941.0K
Q1 25
$-25.6M
$-5.5M
Q4 24
$-28.7M
$1.9M
Q3 24
$-53.3M
$-4.9M
Q2 24
$-38.6M
$6.0M
Q1 24
$-38.2M
$-2.0M
FCF Margin
AGEN
AGEN
SYPR
SYPR
Q4 25
-5.0%
Q3 25
-1.4%
Q2 25
-78.7%
3.0%
Q1 25
-106.5%
-18.8%
Q4 24
-107.0%
5.7%
Q3 24
-212.2%
-13.8%
Q2 24
-164.4%
16.8%
Q1 24
-136.5%
-5.7%
Capex Intensity
AGEN
AGEN
SYPR
SYPR
Q4 25
0.0%
1.3%
Q3 25
0.0%
0.7%
Q2 25
0.0%
0.5%
Q1 25
0.0%
0.0%
Q4 24
0.3%
1.2%
Q3 24
0.0%
0.4%
Q2 24
2.0%
0.5%
Q1 24
0.1%
0.9%
Cash Conversion
AGEN
AGEN
SYPR
SYPR
Q4 25
Q3 25
-0.23×
-0.34×
Q2 25
Q1 25
Q4 24
17.13×
Q3 24
-12.21×
Q2 24
385.25×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AGEN
AGEN

Non Cash Royalty Revenue$31.1M91%
Other$3.2M9%

SYPR
SYPR

Sypris Electronics$17.7M59%
Transferred At Point In Time$12.5M41%

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