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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and BOSTON OMAHA Corp (BOC). Click either name above to swap in a different company.

BOSTON OMAHA Corp is the larger business by last-quarter revenue ($29.7M vs $20.0M, roughly 1.5× AGIOS PHARMACEUTICALS, INC.). BOSTON OMAHA Corp runs the higher net margin — -23.1% vs -541.1%, a 518.0% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 6.4%). BOSTON OMAHA Corp produced more free cash flow last quarter ($-10.0M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 7.8%).

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Boston Omaha Corporation is a publicly traded diversified holding company. Its core operating segments include outdoor advertising, surety insurance, residential real estate development, and fixed wireless broadband services, primarily serving customers across the United States, with a focus on driving long-term shareholder value via strategic acquisitions and organic operational growth.

AGIO vs BOC — Head-to-Head

Bigger by revenue
BOC
BOC
1.5× larger
BOC
$29.7M
$20.0M
AGIO
Growing faster (revenue YoY)
AGIO
AGIO
+79.7% gap
AGIO
86.1%
6.4%
BOC
Higher net margin
BOC
BOC
518.0% more per $
BOC
-23.1%
-541.1%
AGIO
More free cash flow
BOC
BOC
$87.3M more FCF
BOC
$-10.0M
$-97.3M
AGIO
Faster 2-yr revenue CAGR
AGIO
AGIO
Annualised
AGIO
56.1%
7.8%
BOC

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AGIO
AGIO
BOC
BOC
Revenue
$20.0M
$29.7M
Net Profit
$-108.0M
$-6.9M
Gross Margin
90.6%
64.0%
Operating Margin
-608.9%
-4.2%
Net Margin
-541.1%
-23.1%
Revenue YoY
86.1%
6.4%
Net Profit YoY
-11.9%
-228.1%
EPS (diluted)
$-1.86
$-0.23

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGIO
AGIO
BOC
BOC
Q4 25
$20.0M
$29.7M
Q3 25
$12.9M
$28.7M
Q2 25
$12.5M
$28.2M
Q1 25
$8.7M
$27.7M
Q4 24
$10.7M
$27.9M
Q3 24
$9.0M
$27.7M
Q2 24
$8.6M
$27.1M
Q1 24
$8.2M
$25.6M
Net Profit
AGIO
AGIO
BOC
BOC
Q4 25
$-108.0M
$-6.9M
Q3 25
$-103.4M
$-2.6M
Q2 25
$-112.0M
$-2.3M
Q1 25
$-89.3M
$-669.3K
Q4 24
$-96.5M
$5.3M
Q3 24
$947.9M
$-1.6M
Q2 24
$-96.1M
$-2.2M
Q1 24
$-81.5M
$-2.8M
Gross Margin
AGIO
AGIO
BOC
BOC
Q4 25
90.6%
64.0%
Q3 25
87.0%
66.2%
Q2 25
86.3%
66.1%
Q1 25
87.6%
67.3%
Q4 24
88.3%
69.5%
Q3 24
91.3%
67.5%
Q2 24
82.6%
68.2%
Q1 24
92.3%
67.9%
Operating Margin
AGIO
AGIO
BOC
BOC
Q4 25
-608.9%
-4.2%
Q3 25
-907.4%
-3.7%
Q2 25
-1020.1%
-2.9%
Q1 25
-1222.0%
-2.9%
Q4 24
-1165.3%
-4.6%
Q3 24
-1146.9%
-2.7%
Q2 24
-1228.3%
-16.2%
Q1 24
-1124.3%
-8.1%
Net Margin
AGIO
AGIO
BOC
BOC
Q4 25
-541.1%
-23.1%
Q3 25
-803.1%
-9.0%
Q2 25
-899.4%
-8.2%
Q1 25
-1023.3%
-2.4%
Q4 24
-899.6%
19.1%
Q3 24
10574.7%
-5.8%
Q2 24
-1115.7%
-8.3%
Q1 24
-995.8%
-11.0%
EPS (diluted)
AGIO
AGIO
BOC
BOC
Q4 25
$-1.86
$-0.23
Q3 25
$-1.78
$-0.08
Q2 25
$-1.93
$-0.07
Q1 25
$-1.55
$-0.02
Q4 24
$-1.44
$0.17
Q3 24
$16.22
$-0.05
Q2 24
$-1.69
$-0.07
Q1 24
$-1.45
$-0.09

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGIO
AGIO
BOC
BOC
Cash + ST InvestmentsLiquidity on hand
$89.1M
$56.8M
Total DebtLower is stronger
$25.7M
Stockholders' EquityBook value
$1.2B
$516.1M
Total Assets
$1.3B
$713.1M
Debt / EquityLower = less leverage
0.05×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGIO
AGIO
BOC
BOC
Q4 25
$89.1M
$56.8M
Q3 25
$92.7M
$67.6M
Q2 25
$80.9M
$68.6M
Q1 25
$79.0M
$69.2M
Q4 24
$76.2M
$73.2M
Q3 24
$253.7M
$58.6M
Q2 24
$84.5M
$53.1M
Q1 24
$118.8M
$53.4M
Total Debt
AGIO
AGIO
BOC
BOC
Q4 25
$25.7M
Q3 25
$25.9M
Q2 25
$26.1M
Q1 25
$26.3M
Q4 24
$26.5M
Q3 24
$26.7M
Q2 24
$26.9M
Q1 24
$27.1M
Stockholders' Equity
AGIO
AGIO
BOC
BOC
Q4 25
$1.2B
$516.1M
Q3 25
$1.3B
$528.4M
Q2 25
$1.4B
$531.0M
Q1 25
$1.5B
$533.3M
Q4 24
$1.5B
$532.8M
Q3 24
$1.6B
$527.7M
Q2 24
$660.5M
$530.5M
Q1 24
$743.9M
$536.2M
Total Assets
AGIO
AGIO
BOC
BOC
Q4 25
$1.3B
$713.1M
Q3 25
$1.4B
$721.4M
Q2 25
$1.5B
$730.6M
Q1 25
$1.6B
$730.8M
Q4 24
$1.7B
$728.3M
Q3 24
$1.8B
$711.9M
Q2 24
$773.1M
$723.1M
Q1 24
$849.7M
$757.3M
Debt / Equity
AGIO
AGIO
BOC
BOC
Q4 25
0.05×
Q3 25
0.05×
Q2 25
0.05×
Q1 25
0.05×
Q4 24
0.05×
Q3 24
0.05×
Q2 24
0.05×
Q1 24
0.05×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGIO
AGIO
BOC
BOC
Operating Cash FlowLast quarter
$-96.2M
$17.9M
Free Cash FlowOCF − Capex
$-97.3M
$-10.0M
FCF MarginFCF / Revenue
-487.5%
-33.8%
Capex IntensityCapex / Revenue
5.6%
93.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-377.3M
$-17.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGIO
AGIO
BOC
BOC
Q4 25
$-96.2M
$17.9M
Q3 25
$-88.2M
$4.9M
Q2 25
$-77.1M
$4.6M
Q1 25
$-111.5M
$2.6M
Q4 24
$-133.2M
$21.2M
Q3 24
$-84.2M
$5.2M
Q2 24
$-72.6M
$4.5M
Q1 24
$-99.9M
$2.4M
Free Cash Flow
AGIO
AGIO
BOC
BOC
Q4 25
$-97.3M
$-10.0M
Q3 25
$-89.7M
$-489.4K
Q2 25
$-78.0M
$-2.7M
Q1 25
$-112.3M
$-4.3M
Q4 24
$-134.1M
$-11.0M
Q3 24
$-84.6M
$-1.2M
Q2 24
$-72.7M
$-4.3M
Q1 24
$-100.0M
$-6.0M
FCF Margin
AGIO
AGIO
BOC
BOC
Q4 25
-487.5%
-33.8%
Q3 25
-696.5%
-1.7%
Q2 25
-626.2%
-9.7%
Q1 25
-1286.4%
-15.5%
Q4 24
-1250.1%
-39.2%
Q3 24
-944.2%
-4.4%
Q2 24
-844.4%
-15.9%
Q1 24
-1221.2%
-23.6%
Capex Intensity
AGIO
AGIO
BOC
BOC
Q4 25
5.6%
93.9%
Q3 25
12.1%
18.9%
Q2 25
7.0%
25.9%
Q1 25
8.8%
24.7%
Q4 24
9.0%
115.3%
Q3 24
4.7%
23.2%
Q2 24
1.8%
32.6%
Q1 24
1.7%
33.1%
Cash Conversion
AGIO
AGIO
BOC
BOC
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
3.97×
Q3 24
-0.09×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AGIO
AGIO

Segment breakdown not available.

BOC
BOC

Billboard Rentals$11.9M40%
Equity Method Investment Nonconsolidated Investee Or Group Of Investees$10.0M34%
GIG$7.3M25%
Other$608.4K2%

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