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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Five Point Holdings, LLC (FPH). Click either name above to swap in a different company.

AGIOS PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($20.0M vs $13.6M, roughly 1.5× Five Point Holdings, LLC). Five Point Holdings, LLC runs the higher net margin — -16.4% vs -541.1%, a 524.7% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 3.2%). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs -48.5%).

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Five Point Holdings, LLC is a leading U.S. real estate development company that focuses on planning and constructing large-scale master-planned mixed-use communities in high-demand markets across California. Its projects integrate residential housing, commercial office spaces, retail outlets, public amenities and recreational facilities to build vibrant, sustainable living and working environments for local populations.

AGIO vs FPH — Head-to-Head

Bigger by revenue
AGIO
AGIO
1.5× larger
AGIO
$20.0M
$13.6M
FPH
Growing faster (revenue YoY)
AGIO
AGIO
+82.9% gap
AGIO
86.1%
3.2%
FPH
Higher net margin
FPH
FPH
524.7% more per $
FPH
-16.4%
-541.1%
AGIO
Faster 2-yr revenue CAGR
AGIO
AGIO
Annualised
AGIO
56.1%
-48.5%
FPH

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
AGIO
AGIO
FPH
FPH
Revenue
$20.0M
$13.6M
Net Profit
$-108.0M
$-2.2M
Gross Margin
90.6%
Operating Margin
-608.9%
-43.5%
Net Margin
-541.1%
-16.4%
Revenue YoY
86.1%
3.2%
Net Profit YoY
-11.9%
-109.6%
EPS (diluted)
$-1.86

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGIO
AGIO
FPH
FPH
Q1 26
$13.6M
Q4 25
$20.0M
$75.9M
Q3 25
$12.9M
$13.5M
Q2 25
$12.5M
$7.5M
Q1 25
$8.7M
$13.2M
Q4 24
$10.7M
$159.8M
Q3 24
$9.0M
$17.0M
Q2 24
$8.6M
$51.2M
Net Profit
AGIO
AGIO
FPH
FPH
Q1 26
$-2.2M
Q4 25
$-108.0M
$58.7M
Q3 25
$-103.4M
$21.1M
Q2 25
$-112.0M
$3.3M
Q1 25
$-89.3M
$23.3M
Q4 24
$-96.5M
$121.0M
Q3 24
$947.9M
$4.8M
Q2 24
$-96.1M
$14.7M
Gross Margin
AGIO
AGIO
FPH
FPH
Q1 26
Q4 25
90.6%
Q3 25
87.0%
Q2 25
86.3%
Q1 25
87.6%
Q4 24
88.3%
Q3 24
91.3%
Q2 24
82.6%
Operating Margin
AGIO
AGIO
FPH
FPH
Q1 26
-43.5%
Q4 25
-608.9%
89.0%
Q3 25
-907.4%
Q2 25
-1020.1%
Q1 25
-1222.0%
Q4 24
-1165.3%
87.5%
Q3 24
-1146.9%
83.6%
Q2 24
-1228.3%
86.1%
Net Margin
AGIO
AGIO
FPH
FPH
Q1 26
-16.4%
Q4 25
-541.1%
77.3%
Q3 25
-803.1%
156.2%
Q2 25
-899.4%
44.4%
Q1 25
-1023.3%
177.0%
Q4 24
-899.6%
75.7%
Q3 24
10574.7%
28.0%
Q2 24
-1115.7%
28.8%
EPS (diluted)
AGIO
AGIO
FPH
FPH
Q1 26
Q4 25
$-1.86
Q3 25
$-1.78
Q2 25
$-1.93
Q1 25
$-1.55
Q4 24
$-1.44
Q3 24
$16.22
Q2 24
$-1.69

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGIO
AGIO
FPH
FPH
Cash + ST InvestmentsLiquidity on hand
$89.1M
$332.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$2.3B
Total Assets
$1.3B
$3.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGIO
AGIO
FPH
FPH
Q1 26
$332.6M
Q4 25
$89.1M
$425.5M
Q3 25
$92.7M
$351.1M
Q2 25
$80.9M
$456.6M
Q1 25
$79.0M
$528.3M
Q4 24
$76.2M
$430.9M
Q3 24
$253.7M
$224.5M
Q2 24
$84.5M
$217.4M
Stockholders' Equity
AGIO
AGIO
FPH
FPH
Q1 26
$2.3B
Q4 25
$1.2B
$2.3B
Q3 25
$1.3B
$2.3B
Q2 25
$1.4B
$2.2B
Q1 25
$1.5B
$2.2B
Q4 24
$1.5B
$2.2B
Q3 24
$1.6B
$2.0B
Q2 24
$660.5M
$2.0B
Total Assets
AGIO
AGIO
FPH
FPH
Q1 26
$3.2B
Q4 25
$1.3B
$3.2B
Q3 25
$1.4B
$3.2B
Q2 25
$1.5B
$3.2B
Q1 25
$1.6B
$3.2B
Q4 24
$1.7B
$3.1B
Q3 24
$1.8B
$2.9B
Q2 24
$773.1M
$2.9B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGIO
AGIO
FPH
FPH
Operating Cash FlowLast quarter
$-96.2M
$-44.5M
Free Cash FlowOCF − Capex
$-97.3M
FCF MarginFCF / Revenue
-487.5%
Capex IntensityCapex / Revenue
5.6%
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-377.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGIO
AGIO
FPH
FPH
Q1 26
$-44.5M
Q4 25
$-96.2M
$105.2M
Q3 25
$-88.2M
$40.4M
Q2 25
$-77.1M
$-71.6M
Q1 25
$-111.5M
$56.7M
Q4 24
$-133.2M
$116.0M
Q3 24
$-84.2M
$-18.0M
Q2 24
$-72.6M
$-23.2M
Free Cash Flow
AGIO
AGIO
FPH
FPH
Q1 26
Q4 25
$-97.3M
$105.0M
Q3 25
$-89.7M
Q2 25
$-78.0M
$-71.7M
Q1 25
$-112.3M
$56.7M
Q4 24
$-134.1M
$115.2M
Q3 24
$-84.6M
$-18.2M
Q2 24
$-72.7M
$-23.6M
FCF Margin
AGIO
AGIO
FPH
FPH
Q1 26
Q4 25
-487.5%
138.4%
Q3 25
-696.5%
Q2 25
-626.2%
-959.3%
Q1 25
-1286.4%
430.9%
Q4 24
-1250.1%
72.1%
Q3 24
-944.2%
-106.9%
Q2 24
-844.4%
-46.1%
Capex Intensity
AGIO
AGIO
FPH
FPH
Q1 26
0.0%
Q4 25
5.6%
0.3%
Q3 25
12.1%
0.0%
Q2 25
7.0%
0.8%
Q1 25
8.8%
0.3%
Q4 24
9.0%
0.5%
Q3 24
4.7%
1.3%
Q2 24
1.8%
0.7%
Cash Conversion
AGIO
AGIO
FPH
FPH
Q1 26
Q4 25
1.79×
Q3 25
1.92×
Q2 25
-21.58×
Q1 25
2.44×
Q4 24
0.96×
Q3 24
-0.09×
-3.77×
Q2 24
-1.58×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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