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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and FRANKLIN STREET PROPERTIES CORP (FSP). Click either name above to swap in a different company.
FRANKLIN STREET PROPERTIES CORP is the larger business by last-quarter revenue ($26.0M vs $20.0M, roughly 1.3× AGIOS PHARMACEUTICALS, INC.). FRANKLIN STREET PROPERTIES CORP runs the higher net margin — -28.1% vs -541.1%, a 513.0% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs -8.2%). FRANKLIN STREET PROPERTIES CORP produced more free cash flow last quarter ($-12.7M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs -8.7%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
Franklin Street Properties Corp is a Massachusetts-based real estate investment trust (REIT) in the United States. It primarily invests in, owns, and operates high-quality office properties across major U.S. metropolitan markets, serving corporate tenants across various industry segments, and delivers stable long-term returns via rental income and strategic asset management.
AGIO vs FSP — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $26.0M |
| Net Profit | $-108.0M | $-7.3M |
| Gross Margin | 90.6% | 59.4% |
| Operating Margin | -608.9% | -27.9% |
| Net Margin | -541.1% | -28.1% |
| Revenue YoY | 86.1% | -8.2% |
| Net Profit YoY | -11.9% | 14.1% |
| EPS (diluted) | $-1.86 | $-0.06 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $26.0M | ||
| Q3 25 | $12.9M | $27.3M | ||
| Q2 25 | $12.5M | $26.7M | ||
| Q1 25 | $8.7M | $27.1M | ||
| Q4 24 | $10.7M | $28.4M | ||
| Q3 24 | $9.0M | $29.7M | ||
| Q2 24 | $8.6M | $30.8M | ||
| Q1 24 | $8.2M | $31.2M |
| Q4 25 | $-108.0M | $-7.3M | ||
| Q3 25 | $-103.4M | $-8.3M | ||
| Q2 25 | $-112.0M | $-7.9M | ||
| Q1 25 | $-89.3M | $-21.4M | ||
| Q4 24 | $-96.5M | $-8.5M | ||
| Q3 24 | $947.9M | $-15.6M | ||
| Q2 24 | $-96.1M | $-21.0M | ||
| Q1 24 | $-81.5M | $-7.6M |
| Q4 25 | 90.6% | 59.4% | ||
| Q3 25 | 87.0% | 60.9% | ||
| Q2 25 | 86.3% | 59.9% | ||
| Q1 25 | 87.6% | 62.8% | ||
| Q4 24 | 88.3% | 59.7% | ||
| Q3 24 | 91.3% | 61.0% | ||
| Q2 24 | 82.6% | 64.2% | ||
| Q1 24 | 92.3% | 64.7% |
| Q4 25 | -608.9% | -27.9% | ||
| Q3 25 | -907.4% | -30.5% | ||
| Q2 25 | -1020.1% | -29.2% | ||
| Q1 25 | -1222.0% | -78.9% | ||
| Q4 24 | -1165.3% | -29.9% | ||
| Q3 24 | -1146.9% | -52.4% | ||
| Q2 24 | -1228.3% | -68.0% | ||
| Q1 24 | -1124.3% | -24.0% |
| Q4 25 | -541.1% | -28.1% | ||
| Q3 25 | -803.1% | -30.5% | ||
| Q2 25 | -899.4% | -29.5% | ||
| Q1 25 | -1023.3% | -79.1% | ||
| Q4 24 | -899.6% | -30.0% | ||
| Q3 24 | 10574.7% | -52.6% | ||
| Q2 24 | -1115.7% | -68.2% | ||
| Q1 24 | -995.8% | -24.2% |
| Q4 25 | $-1.86 | $-0.06 | ||
| Q3 25 | $-1.78 | $-0.08 | ||
| Q2 25 | $-1.93 | $-0.08 | ||
| Q1 25 | $-1.55 | $-0.21 | ||
| Q4 24 | $-1.44 | $-0.09 | ||
| Q3 24 | $16.22 | $-0.15 | ||
| Q2 24 | $-1.69 | $-0.20 | ||
| Q1 24 | $-1.45 | $-0.07 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $30.6M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.2B | $607.0M |
| Total Assets | $1.3B | $892.9M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $30.6M | ||
| Q3 25 | $92.7M | $31.4M | ||
| Q2 25 | $80.9M | $29.4M | ||
| Q1 25 | $79.0M | $30.2M | ||
| Q4 24 | $76.2M | $41.1M | ||
| Q3 24 | $253.7M | $40.9M | ||
| Q2 24 | $84.5M | $30.2M | ||
| Q1 24 | $118.8M | $34.2M |
| Q4 25 | $1.2B | $607.0M | ||
| Q3 25 | $1.3B | $615.3M | ||
| Q2 25 | $1.4B | $624.7M | ||
| Q1 25 | $1.5B | $633.4M | ||
| Q4 24 | $1.5B | $655.9M | ||
| Q3 24 | $1.6B | $665.4M | ||
| Q2 24 | $660.5M | $682.1M | ||
| Q1 24 | $743.9M | $703.9M |
| Q4 25 | $1.3B | $892.9M | ||
| Q3 25 | $1.4B | $901.0M | ||
| Q2 25 | $1.5B | $903.2M | ||
| Q1 25 | $1.6B | $916.4M | ||
| Q4 24 | $1.7B | $946.9M | ||
| Q3 24 | $1.8B | $981.5M | ||
| Q2 24 | $773.1M | $1.0B | ||
| Q1 24 | $849.7M | $1.0B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $3.8M |
| Free Cash FlowOCF − Capex | $-97.3M | $-12.7M |
| FCF MarginFCF / Revenue | -487.5% | -48.6% |
| Capex IntensityCapex / Revenue | 5.6% | 63.0% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $-25.3M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $3.8M | ||
| Q3 25 | $-88.2M | $8.3M | ||
| Q2 25 | $-77.1M | $-2.9M | ||
| Q1 25 | $-111.5M | $-5.5M | ||
| Q4 24 | $-133.2M | $9.0M | ||
| Q3 24 | $-84.2M | $14.5M | ||
| Q2 24 | $-72.6M | $-648.0K | ||
| Q1 24 | $-99.9M | $-7.1M |
| Q4 25 | $-97.3M | $-12.7M | ||
| Q3 25 | $-89.7M | $3.0M | ||
| Q2 25 | $-78.0M | $-5.7M | ||
| Q1 25 | $-112.3M | $-9.9M | ||
| Q4 24 | $-134.1M | $-16.2M | ||
| Q3 24 | $-84.6M | $8.6M | ||
| Q2 24 | $-72.7M | $-5.1M | ||
| Q1 24 | $-100.0M | $-15.8M |
| Q4 25 | -487.5% | -48.6% | ||
| Q3 25 | -696.5% | 11.0% | ||
| Q2 25 | -626.2% | -21.5% | ||
| Q1 25 | -1286.4% | -36.7% | ||
| Q4 24 | -1250.1% | -57.2% | ||
| Q3 24 | -944.2% | 29.1% | ||
| Q2 24 | -844.4% | -16.7% | ||
| Q1 24 | -1221.2% | -50.8% |
| Q4 25 | 5.6% | 63.0% | ||
| Q3 25 | 12.1% | 19.4% | ||
| Q2 25 | 7.0% | 10.7% | ||
| Q1 25 | 8.8% | 16.4% | ||
| Q4 24 | 9.0% | 88.9% | ||
| Q3 24 | 4.7% | 19.6% | ||
| Q2 24 | 1.8% | 14.6% | ||
| Q1 24 | 1.7% | 28.1% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | -0.09× | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
