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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Orange County Bancorp, Inc. (OBT). Click either name above to swap in a different company.

Orange County Bancorp, Inc. is the larger business by last-quarter revenue ($33.0M vs $20.0M, roughly 1.7× AGIOS PHARMACEUTICALS, INC.). Orange County Bancorp, Inc. runs the higher net margin — 37.6% vs -541.1%, a 578.7% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 20.6%). Orange County Bancorp, Inc. produced more free cash flow last quarter ($41.3M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 14.3%).

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Orange County Bancorp, Inc. is a Delaware-registered bank holding company operating mainly in New York, U.S. It offers a full range of retail and commercial banking services, including deposit accounts, loans and wealth management solutions, serving individual consumers, small and mid-sized corporate clients in its regional footprint.

AGIO vs OBT — Head-to-Head

Bigger by revenue
OBT
OBT
1.7× larger
OBT
$33.0M
$20.0M
AGIO
Growing faster (revenue YoY)
AGIO
AGIO
+65.5% gap
AGIO
86.1%
20.6%
OBT
Higher net margin
OBT
OBT
578.7% more per $
OBT
37.6%
-541.1%
AGIO
More free cash flow
OBT
OBT
$138.7M more FCF
OBT
$41.3M
$-97.3M
AGIO
Faster 2-yr revenue CAGR
AGIO
AGIO
Annualised
AGIO
56.1%
14.3%
OBT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AGIO
AGIO
OBT
OBT
Revenue
$20.0M
$33.0M
Net Profit
$-108.0M
$12.4M
Gross Margin
90.6%
Operating Margin
-608.9%
41.4%
Net Margin
-541.1%
37.6%
Revenue YoY
86.1%
20.6%
Net Profit YoY
-11.9%
73.5%
EPS (diluted)
$-1.86
$0.94

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGIO
AGIO
OBT
OBT
Q4 25
$20.0M
$33.0M
Q3 25
$12.9M
$33.7M
Q2 25
$12.5M
$32.5M
Q1 25
$8.7M
$28.0M
Q4 24
$10.7M
$27.4M
Q3 24
$9.0M
$27.1M
Q2 24
$8.6M
$27.9M
Q1 24
$8.2M
$25.3M
Net Profit
AGIO
AGIO
OBT
OBT
Q4 25
$-108.0M
$12.4M
Q3 25
$-103.4M
$10.0M
Q2 25
$-112.0M
$10.5M
Q1 25
$-89.3M
$8.7M
Q4 24
$-96.5M
$7.2M
Q3 24
$947.9M
$3.2M
Q2 24
$-96.1M
$8.2M
Q1 24
$-81.5M
$9.3M
Gross Margin
AGIO
AGIO
OBT
OBT
Q4 25
90.6%
Q3 25
87.0%
Q2 25
86.3%
Q1 25
87.6%
Q4 24
88.3%
Q3 24
91.3%
Q2 24
82.6%
Q1 24
92.3%
Operating Margin
AGIO
AGIO
OBT
OBT
Q4 25
-608.9%
41.4%
Q3 25
-907.4%
38.6%
Q2 25
-1020.1%
41.9%
Q1 25
-1222.0%
40.3%
Q4 24
-1165.3%
32.8%
Q3 24
-1146.9%
14.8%
Q2 24
-1228.3%
36.6%
Q1 24
-1124.3%
45.9%
Net Margin
AGIO
AGIO
OBT
OBT
Q4 25
-541.1%
37.6%
Q3 25
-803.1%
29.7%
Q2 25
-899.4%
32.2%
Q1 25
-1023.3%
31.1%
Q4 24
-899.6%
26.2%
Q3 24
10574.7%
11.8%
Q2 24
-1115.7%
29.4%
Q1 24
-995.8%
36.7%
EPS (diluted)
AGIO
AGIO
OBT
OBT
Q4 25
$-1.86
$0.94
Q3 25
$-1.78
$0.75
Q2 25
$-1.93
$0.87
Q1 25
$-1.55
$0.77
Q4 24
$-1.44
$0.64
Q3 24
$16.22
$0.28
Q2 24
$-1.69
$0.73
Q1 24
$-1.45
$0.82

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGIO
AGIO
OBT
OBT
Cash + ST InvestmentsLiquidity on hand
$89.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$284.4M
Total Assets
$1.3B
$2.7B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGIO
AGIO
OBT
OBT
Q4 25
$89.1M
Q3 25
$92.7M
Q2 25
$80.9M
Q1 25
$79.0M
Q4 24
$76.2M
Q3 24
$253.7M
Q2 24
$84.5M
Q1 24
$118.8M
Stockholders' Equity
AGIO
AGIO
OBT
OBT
Q4 25
$1.2B
$284.4M
Q3 25
$1.3B
$270.1M
Q2 25
$1.4B
$252.6M
Q1 25
$1.5B
$201.3M
Q4 24
$1.5B
$185.5M
Q3 24
$1.6B
$193.1M
Q2 24
$660.5M
$177.5M
Q1 24
$743.9M
$168.7M
Total Assets
AGIO
AGIO
OBT
OBT
Q4 25
$1.3B
$2.7B
Q3 25
$1.4B
$2.6B
Q2 25
$1.5B
$2.6B
Q1 25
$1.6B
$2.6B
Q4 24
$1.7B
$2.5B
Q3 24
$1.8B
$2.5B
Q2 24
$773.1M
$2.5B
Q1 24
$849.7M
$2.5B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGIO
AGIO
OBT
OBT
Operating Cash FlowLast quarter
$-96.2M
$43.8M
Free Cash FlowOCF − Capex
$-97.3M
$41.3M
FCF MarginFCF / Revenue
-487.5%
125.1%
Capex IntensityCapex / Revenue
5.6%
7.6%
Cash ConversionOCF / Net Profit
3.53×
TTM Free Cash FlowTrailing 4 quarters
$-377.3M
$69.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGIO
AGIO
OBT
OBT
Q4 25
$-96.2M
$43.8M
Q3 25
$-88.2M
$30.2M
Q2 25
$-77.1M
$-5.0M
Q1 25
$-111.5M
$4.8M
Q4 24
$-133.2M
$34.6M
Q3 24
$-84.2M
$10.2M
Q2 24
$-72.6M
$9.3M
Q1 24
$-99.9M
$2.3M
Free Cash Flow
AGIO
AGIO
OBT
OBT
Q4 25
$-97.3M
$41.3M
Q3 25
$-89.7M
$29.6M
Q2 25
$-78.0M
$-5.7M
Q1 25
$-112.3M
$4.3M
Q4 24
$-134.1M
$32.9M
Q3 24
$-84.6M
$10.0M
Q2 24
$-72.7M
$9.2M
Q1 24
$-100.0M
$2.0M
FCF Margin
AGIO
AGIO
OBT
OBT
Q4 25
-487.5%
125.1%
Q3 25
-696.5%
87.8%
Q2 25
-626.2%
-17.5%
Q1 25
-1286.4%
15.5%
Q4 24
-1250.1%
120.0%
Q3 24
-944.2%
36.7%
Q2 24
-844.4%
32.8%
Q1 24
-1221.2%
7.9%
Capex Intensity
AGIO
AGIO
OBT
OBT
Q4 25
5.6%
7.6%
Q3 25
12.1%
1.8%
Q2 25
7.0%
2.3%
Q1 25
8.8%
1.8%
Q4 24
9.0%
6.3%
Q3 24
4.7%
1.1%
Q2 24
1.8%
0.4%
Q1 24
1.7%
1.0%
Cash Conversion
AGIO
AGIO
OBT
OBT
Q4 25
3.53×
Q3 25
3.01×
Q2 25
-0.47×
Q1 25
0.56×
Q4 24
4.83×
Q3 24
-0.09×
3.19×
Q2 24
1.13×
Q1 24
0.24×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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