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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Postal Realty Trust, Inc. (PSTL). Click either name above to swap in a different company.
Postal Realty Trust, Inc. is the larger business by last-quarter revenue ($26.0M vs $20.0M, roughly 1.3× AGIOS PHARMACEUTICALS, INC.). Postal Realty Trust, Inc. runs the higher net margin — 17.9% vs -541.1%, a 558.9% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 21.7%). Postal Realty Trust, Inc. produced more free cash flow last quarter ($37.6M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 22.6%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
Postal Realty Trust, Inc. is a specialized real estate investment trust that acquires, owns, and manages properties primarily leased to the United States Postal Service. Its portfolio includes last-mile postal facilities, sorting centers, and retail post office locations across the U.S., supporting critical mail and package delivery infrastructure.
AGIO vs PSTL — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $26.0M |
| Net Profit | $-108.0M | $4.6M |
| Gross Margin | 90.6% | — |
| Operating Margin | -608.9% | 39.2% |
| Net Margin | -541.1% | 17.9% |
| Revenue YoY | 86.1% | 21.7% |
| Net Profit YoY | -11.9% | 3.1% |
| EPS (diluted) | $-1.86 | $0.16 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $26.0M | ||
| Q3 25 | $12.9M | $24.3M | ||
| Q2 25 | $12.5M | $23.4M | ||
| Q1 25 | $8.7M | $22.1M | ||
| Q4 24 | $10.7M | $21.4M | ||
| Q3 24 | $9.0M | $19.7M | ||
| Q2 24 | $8.6M | $18.1M | ||
| Q1 24 | $8.2M | $17.3M |
| Q4 25 | $-108.0M | $4.6M | ||
| Q3 25 | $-103.4M | $3.8M | ||
| Q2 25 | $-112.0M | $3.6M | ||
| Q1 25 | $-89.3M | $2.1M | ||
| Q4 24 | $-96.5M | $4.5M | ||
| Q3 24 | $947.9M | $1.1M | ||
| Q2 24 | $-96.1M | $817.0K | ||
| Q1 24 | $-81.5M | $206.0K |
| Q4 25 | 90.6% | — | ||
| Q3 25 | 87.0% | — | ||
| Q2 25 | 86.3% | — | ||
| Q1 25 | 87.6% | — | ||
| Q4 24 | 88.3% | — | ||
| Q3 24 | 91.3% | — | ||
| Q2 24 | 82.6% | — | ||
| Q1 24 | 92.3% | — |
| Q4 25 | -608.9% | 39.2% | ||
| Q3 25 | -907.4% | 37.6% | ||
| Q2 25 | -1020.1% | 37.3% | ||
| Q1 25 | -1222.0% | 28.4% | ||
| Q4 24 | -1165.3% | 43.2% | ||
| Q3 24 | -1146.9% | 24.3% | ||
| Q2 24 | -1228.3% | 22.8% | ||
| Q1 24 | -1124.3% | 17.6% |
| Q4 25 | -541.1% | 17.9% | ||
| Q3 25 | -803.1% | 15.7% | ||
| Q2 25 | -899.4% | 15.5% | ||
| Q1 25 | -1023.3% | 9.4% | ||
| Q4 24 | -899.6% | 21.1% | ||
| Q3 24 | 10574.7% | 5.4% | ||
| Q2 24 | -1115.7% | 4.5% | ||
| Q1 24 | -995.8% | 1.2% |
| Q4 25 | $-1.86 | $0.16 | ||
| Q3 25 | $-1.78 | $0.13 | ||
| Q2 25 | $-1.93 | $0.12 | ||
| Q1 25 | $-1.55 | $0.06 | ||
| Q4 24 | $-1.44 | $0.17 | ||
| Q3 24 | $16.22 | $0.03 | ||
| Q2 24 | $-1.69 | $0.02 | ||
| Q1 24 | $-1.45 | $-0.01 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $1.5M |
| Total DebtLower is stronger | — | $361.1M |
| Stockholders' EquityBook value | $1.2B | $285.2M |
| Total Assets | $1.3B | $759.1M |
| Debt / EquityLower = less leverage | — | 1.27× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $1.5M | ||
| Q3 25 | $92.7M | $1.9M | ||
| Q2 25 | $80.9M | $1.1M | ||
| Q1 25 | $79.0M | $639.0K | ||
| Q4 24 | $76.2M | $1.8M | ||
| Q3 24 | $253.7M | $970.0K | ||
| Q2 24 | $84.5M | $1.7M | ||
| Q1 24 | $118.8M | $1.9M |
| Q4 25 | — | $361.1M | ||
| Q3 25 | — | $347.0M | ||
| Q2 25 | — | $328.8M | ||
| Q1 25 | — | $306.7M | ||
| Q4 24 | — | $296.7M | ||
| Q3 24 | — | $277.0M | ||
| Q2 24 | — | $273.7M | ||
| Q1 24 | — | $247.6M |
| Q4 25 | $1.2B | $285.2M | ||
| Q3 25 | $1.3B | $273.9M | ||
| Q2 25 | $1.4B | $250.8M | ||
| Q1 25 | $1.5B | $245.5M | ||
| Q4 24 | $1.5B | $251.3M | ||
| Q3 24 | $1.6B | $245.6M | ||
| Q2 24 | $660.5M | $245.5M | ||
| Q1 24 | $743.9M | $248.1M |
| Q4 25 | $1.3B | $759.1M | ||
| Q3 25 | $1.4B | $735.2M | ||
| Q2 25 | $1.5B | $689.8M | ||
| Q1 25 | $1.6B | $654.0M | ||
| Q4 24 | $1.7B | $646.8M | ||
| Q3 24 | $1.8B | $615.1M | ||
| Q2 24 | $773.1M | $608.2M | ||
| Q1 24 | $849.7M | $584.1M |
| Q4 25 | — | 1.27× | ||
| Q3 25 | — | 1.27× | ||
| Q2 25 | — | 1.31× | ||
| Q1 25 | — | 1.25× | ||
| Q4 24 | — | 1.18× | ||
| Q3 24 | — | 1.13× | ||
| Q2 24 | — | 1.11× | ||
| Q1 24 | — | 1.00× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $44.5M |
| Free Cash FlowOCF − Capex | $-97.3M | $37.6M |
| FCF MarginFCF / Revenue | -487.5% | 144.5% |
| Capex IntensityCapex / Revenue | 5.6% | 26.7% |
| Cash ConversionOCF / Net Profit | — | 9.59× |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $65.6M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $44.5M | ||
| Q3 25 | $-88.2M | $10.9M | ||
| Q2 25 | $-77.1M | $11.4M | ||
| Q1 25 | $-111.5M | $10.8M | ||
| Q4 24 | $-133.2M | $33.5M | ||
| Q3 24 | $-84.2M | $8.0M | ||
| Q2 24 | $-72.6M | $9.9M | ||
| Q1 24 | $-99.9M | $6.4M |
| Q4 25 | $-97.3M | $37.6M | ||
| Q3 25 | $-89.7M | $8.8M | ||
| Q2 25 | $-78.0M | $9.1M | ||
| Q1 25 | $-112.3M | $10.2M | ||
| Q4 24 | $-134.1M | $30.7M | ||
| Q3 24 | $-84.6M | $7.4M | ||
| Q2 24 | $-72.7M | $8.9M | ||
| Q1 24 | $-100.0M | $5.8M |
| Q4 25 | -487.5% | 144.5% | ||
| Q3 25 | -696.5% | 36.1% | ||
| Q2 25 | -626.2% | 38.8% | ||
| Q1 25 | -1286.4% | 45.9% | ||
| Q4 24 | -1250.1% | 143.8% | ||
| Q3 24 | -944.2% | 37.6% | ||
| Q2 24 | -844.4% | 49.4% | ||
| Q1 24 | -1221.2% | 33.6% |
| Q4 25 | 5.6% | 26.7% | ||
| Q3 25 | 12.1% | 8.9% | ||
| Q2 25 | 7.0% | 10.1% | ||
| Q1 25 | 8.8% | 3.0% | ||
| Q4 24 | 9.0% | 13.0% | ||
| Q3 24 | 4.7% | 3.2% | ||
| Q2 24 | 1.8% | 5.4% | ||
| Q1 24 | 1.7% | 3.5% |
| Q4 25 | — | 9.59× | ||
| Q3 25 | — | 2.87× | ||
| Q2 25 | — | 3.16× | ||
| Q1 25 | — | 5.20× | ||
| Q4 24 | — | 7.44× | ||
| Q3 24 | -0.09× | 7.48× | ||
| Q2 24 | — | 12.10× | ||
| Q1 24 | — | 31.07× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
