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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Rent the Runway, Inc. (RENT). Click either name above to swap in a different company.

AGIOS PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($20.0M vs $10.6M, roughly 1.9× Rent the Runway, Inc.). Rent the Runway, Inc. runs the higher net margin — 721.7% vs -541.1%, a 1262.8% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 10.4%). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 1.0%).

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Rent the Runway is an American e-commerce platform that allows users to rent, subscribe, or buy designer apparel and accessories. It was founded in November 2009 by Jennifer Hyman and Jennifer Fleiss and is based in New York City.

AGIO vs RENT — Head-to-Head

Bigger by revenue
AGIO
AGIO
1.9× larger
AGIO
$20.0M
$10.6M
RENT
Growing faster (revenue YoY)
AGIO
AGIO
+75.7% gap
AGIO
86.1%
10.4%
RENT
Higher net margin
RENT
RENT
1262.8% more per $
RENT
721.7%
-541.1%
AGIO
Faster 2-yr revenue CAGR
AGIO
AGIO
Annualised
AGIO
56.1%
1.0%
RENT

Income Statement — Q4 FY2025 vs Q3 FY2026

Metric
AGIO
AGIO
RENT
RENT
Revenue
$20.0M
$10.6M
Net Profit
$-108.0M
$76.5M
Gross Margin
90.6%
-126.4%
Operating Margin
-608.9%
-152.8%
Net Margin
-541.1%
721.7%
Revenue YoY
86.1%
10.4%
Net Profit YoY
-11.9%
504.8%
EPS (diluted)
$-1.86
$13.65

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGIO
AGIO
RENT
RENT
Q4 25
$20.0M
$10.6M
Q3 25
$12.9M
$11.7M
Q2 25
$12.5M
$7.6M
Q1 25
$8.7M
$11.8M
Q4 24
$10.7M
$9.6M
Q3 24
$9.0M
$10.4M
Q2 24
$8.6M
$8.9M
Q1 24
$8.2M
$10.4M
Net Profit
AGIO
AGIO
RENT
RENT
Q4 25
$-108.0M
$76.5M
Q3 25
$-103.4M
$-26.4M
Q2 25
$-112.0M
$-26.1M
Q1 25
$-89.3M
$-13.4M
Q4 24
$-96.5M
$-18.9M
Q3 24
$947.9M
$-15.6M
Q2 24
$-96.1M
$-22.0M
Q1 24
$-81.5M
$-24.8M
Gross Margin
AGIO
AGIO
RENT
RENT
Q4 25
90.6%
-126.4%
Q3 25
87.0%
-92.3%
Q2 25
86.3%
-168.4%
Q1 25
87.6%
-71.2%
Q4 24
88.3%
-122.9%
Q3 24
91.3%
-98.1%
Q2 24
82.6%
-131.5%
Q1 24
92.3%
-93.3%
Operating Margin
AGIO
AGIO
RENT
RENT
Q4 25
-608.9%
-152.8%
Q3 25
-907.4%
-171.8%
Q2 25
-1020.1%
-259.2%
Q1 25
-1222.0%
-65.3%
Q4 24
-1165.3%
-142.7%
Q3 24
-1146.9%
-92.3%
Q2 24
-1228.3%
-185.4%
Q1 24
-1124.3%
-185.6%
Net Margin
AGIO
AGIO
RENT
RENT
Q4 25
-541.1%
721.7%
Q3 25
-803.1%
-225.6%
Q2 25
-899.4%
-343.4%
Q1 25
-1023.3%
-113.6%
Q4 24
-899.6%
-196.9%
Q3 24
10574.7%
-150.0%
Q2 24
-1115.7%
-247.2%
Q1 24
-995.8%
-238.5%
EPS (diluted)
AGIO
AGIO
RENT
RENT
Q4 25
$-1.86
$13.65
Q3 25
$-1.78
$-6.55
Q2 25
$-1.93
$-6.58
Q1 25
$-1.55
$-2.72
Q4 24
$-1.44
$-4.70
Q3 24
$16.22
$-4.17
Q2 24
$-1.69
$-6.03
Q1 24
$-1.45
$-5.36

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGIO
AGIO
RENT
RENT
Cash + ST InvestmentsLiquidity on hand
$89.1M
$50.7M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$-35.1M
Total Assets
$1.3B
$231.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGIO
AGIO
RENT
RENT
Q4 25
$89.1M
$50.7M
Q3 25
$92.7M
$43.6M
Q2 25
$80.9M
$70.4M
Q1 25
$79.0M
$77.4M
Q4 24
$76.2M
$74.1M
Q3 24
$253.7M
$76.6M
Q2 24
$84.5M
$82.0M
Q1 24
$118.8M
$84.0M
Total Debt
AGIO
AGIO
RENT
RENT
Q4 25
Q3 25
Q2 25
$340.6M
Q1 25
$333.7M
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
AGIO
AGIO
RENT
RENT
Q4 25
$1.2B
$-35.1M
Q3 25
$1.3B
$-232.1M
Q2 25
$1.4B
$-207.1M
Q1 25
$1.5B
$-182.5M
Q4 24
$1.5B
$-171.2M
Q3 24
$1.6B
$-154.5M
Q2 24
$660.5M
$-141.3M
Q1 24
$743.9M
$-122.3M
Total Assets
AGIO
AGIO
RENT
RENT
Q4 25
$1.3B
$231.0M
Q3 25
$1.4B
$219.0M
Q2 25
$1.5B
$245.3M
Q1 25
$1.6B
$240.0M
Q4 24
$1.7B
$251.6M
Q3 24
$1.8B
$257.4M
Q2 24
$773.1M
$278.4M
Q1 24
$849.7M
$278.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGIO
AGIO
RENT
RENT
Operating Cash FlowLast quarter
$-96.2M
$-1.4M
Free Cash FlowOCF − Capex
$-97.3M
FCF MarginFCF / Revenue
-487.5%
Capex IntensityCapex / Revenue
5.6%
Cash ConversionOCF / Net Profit
-0.02×
TTM Free Cash FlowTrailing 4 quarters
$-377.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGIO
AGIO
RENT
RENT
Q4 25
$-96.2M
$-1.4M
Q3 25
$-88.2M
$-10.5M
Q2 25
$-77.1M
$8.3M
Q1 25
$-111.5M
$1.4M
Q4 24
$-133.2M
$4.7M
Q3 24
$-84.2M
$2.2M
Q2 24
$-72.6M
$4.6M
Q1 24
$-99.9M
$-8.0M
Free Cash Flow
AGIO
AGIO
RENT
RENT
Q4 25
$-97.3M
Q3 25
$-89.7M
Q2 25
$-78.0M
Q1 25
$-112.3M
Q4 24
$-134.1M
Q3 24
$-84.6M
Q2 24
$-72.7M
Q1 24
$-100.0M
FCF Margin
AGIO
AGIO
RENT
RENT
Q4 25
-487.5%
Q3 25
-696.5%
Q2 25
-626.2%
Q1 25
-1286.4%
Q4 24
-1250.1%
Q3 24
-944.2%
Q2 24
-844.4%
Q1 24
-1221.2%
Capex Intensity
AGIO
AGIO
RENT
RENT
Q4 25
5.6%
Q3 25
12.1%
Q2 25
7.0%
Q1 25
8.8%
Q4 24
9.0%
Q3 24
4.7%
Q2 24
1.8%
Q1 24
1.7%
Cash Conversion
AGIO
AGIO
RENT
RENT
Q4 25
-0.02×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
-0.09×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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